Flavonoids Inhibit Heparin-Induced Aggregation of the Third Repeat (R3) of Microtubule-Binding Domain of Alzheimer’s Tau Protein

2010 ◽  
Vol 83 (8) ◽  
pp. 911-922 ◽  
Author(s):  
Lin-Jie Han ◽  
Shuo Shi ◽  
Leng-Feng Zheng ◽  
Dan-Jing Yang ◽  
Tian-Ming Yao ◽  
...  
Keyword(s):  
Tau Protein ◽  
Binding Domain ◽  
Microtubule Binding ◽  
The Third ◽  
Microtubule Binding Domain ◽  
Induced Aggregation

Importance of Tyr310 residue in the third repeat of microtubule binding domain for filament formation of tau protein

2009 ◽  
Vol 147 (3) ◽  
pp. 405-414 ◽  
Author(s):  
Chisato Nishiura ◽  
Kengo Takeuchi ◽  
Katsuhiko Minoura ◽  
Miho Sumida ◽  
Taizo Taniguchi ◽  
...  
Keyword(s):  
Tau Protein ◽  
Binding Domain ◽  
Filament Formation ◽  
Microtubule Binding ◽  
The Third ◽  
Microtubule Binding Domain

Conformational transition state is responsible for assembly of microtubule-binding domain of tau protein

2004 ◽  
Vol 315 (3) ◽  
pp. 659-663 ◽  
Author(s):  
Shuko Hiraoka ◽  
Tian-Ming Yao ◽  
Katsuhiko Minoura ◽  
Koji Tomoo ◽  
Miho Sumida ◽  
...  
Keyword(s):  
Transition State ◽  
Tau Protein ◽  
Conformational Transition ◽  
Binding Domain ◽  
Microtubule Binding ◽  
Microtubule Binding Domain

Possible Role of Each Repeat Structure of the Microtubule-Binding Domain of the Tau Protein in In Vitro Aggregation

2005 ◽  
Vol 138 (4) ◽  
pp. 413-423 ◽  
Author(s):  
Koji Tomoo ◽  
Tian-Ming Yao ◽  
Katsuhiko Minoura ◽  
Shuko Hiraoka ◽  
Miho Sumida ◽  
...  
Keyword(s):  
Tau Protein ◽  
Binding Domain ◽  
Microtubule Binding ◽  
Repeat Structure ◽  
Microtubule Binding Domain

Amphipathic helical behavior of the third repeat fragment in the tau microtubule-binding domain, studied by 1H NMR spectroscopy

2002 ◽  
Vol 294 (2) ◽  
pp. 210-214 ◽  
Author(s):  
Katsuhiko Minoura ◽  
Koji Tomoo ◽  
Toshimasa Ishida ◽  
Hiroshi Hasegawa ◽  
Masahiro Sasaki ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
1H Nmr Spectroscopy ◽  
Binding Domain ◽  
Microtubule Binding ◽  
The Third ◽  
Microtubule Binding Domain

The microtubule binding domain of tau protein

Neuron ◽  
1989 ◽  
Vol 2 (6) ◽  
pp. 1615-1624 ◽  
Author(s):  
Gloria Lee ◽  
Rachael L. Neve ◽  
Kenneth S. Kosik
Keyword(s):  
Tau Protein ◽  
Binding Domain ◽  
Microtubule Binding ◽  
Microtubule Binding Domain
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