Aza-Michael Reactions in Ionic Liquids. A Facile Synthesis of β-Amino Compounds

2003 ◽  
Vol 32 (11) ◽  
pp. 988-989 ◽  
Author(s):  
J. S. Yadav ◽  
B. V. S. Reddy ◽  
A. K. Basak ◽  
A. V. Narsaiah
ChemInform ◽  
2004 ◽  
Vol 35 (14) ◽  
Author(s):  
J. S. Yadav ◽  
B. V. S. Reddy ◽  
A. K. Basak ◽  
A. V. Narsaiah

2005 ◽  
Vol 35 (4) ◽  
pp. 521-526 ◽  
Author(s):  
Dingjun Zhang ◽  
Jianmin Chen ◽  
Yongming Liang ◽  
Huidi Zhou

ChemInform ◽  
2005 ◽  
Vol 36 (1) ◽  
Author(s):  
J. S. Yadav ◽  
B. V. S. Reddy ◽  
V. Naveenkumar ◽  
R. Srinivasa Rao ◽  
K. Nagaiah

2009 ◽  
Vol 48 (15) ◽  
pp. 7437-7441 ◽  
Author(s):  
Jongho Kim ◽  
Sang Wook Kang ◽  
Sung Hyun Mun ◽  
Yong Soo Kang

Catalysts ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 814
Author(s):  
Katia Bacha ◽  
Kawther Aguibi ◽  
Jean-Pierre Mbakidi ◽  
Sandrine Bouquillon

We developed a synthesis of chiral ionic liquids from proline and one of its derivatives. Nine chiral ionic liquids were synthesized with yields from 78% to 95%. These synthesized ionic liquids played two roles in Michael reactions, as solvents, and as basic catalysts, where the ionic phase could also be reused at least five times without loss of activity. The yields up to 99% were improved by increasing the amount of dimethylmalonate from 1.2 equivalents to 3 or 4 equivalents. Furthermore, the reaction time could be reduced from 24 h to 45 min through microwaves activation.


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