scholarly journals Studies on cardiotonic agents. VI. Synthesis of novel 4,5-dihydro-3(2H)-pyridazinone derivatives carrying some benzoheterocycles at the 6-position.

1991 ◽  
Vol 39 (2) ◽  
pp. 352-357 ◽  
Author(s):  
Yuji NOMOTO ◽  
Haruki TAKAI ◽  
Tetsuji OHNO ◽  
Kazuhiro KUBO
Keyword(s):  
Cardiotonic Agents ◽  
Pyridazinone Derivatives

Diverse chemical and biological potentials of various pyridazine and pyridazinone derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Wide Spectrum ◽  
Biological Properties ◽  
Industrial Chemical ◽  
Anti Inflammatory ◽  
Pyridazinone Derivatives

A series of heterocyclic compounds incorporating pyridazine moiety were for diverse biological activities. Pyridazines and pyridazinones derivatives showed wide spectrum of biological activities such as vasodialator, cardiotonic, anticonvulsant, antihypertensive, antimicrobial, anti-inflammatory, analgesic, anti-feedant, herbicidal, and various other biological, agrochemical and industrial chemical activities. The results illustrated that the synthesized pyridazine/pyridazine compounds have diverse and significant biological activities. Mechanistic insights into the biological properties of pyridazinone derivatives and various synthetic techniques used for their synthesis are also described.

Pyridazinone derivatives: Design, synthesis, and in vitro vasorelaxant activity

2008 ◽  
Vol 16 (1) ◽  
pp. 382-389 ◽  
Author(s):  
Khaled Abouzid ◽  
Maha Abdel Hakeem ◽  
Omnya Khalil ◽  
Yosria Maklad
Keyword(s):  
Design Synthesis ◽  
Vasorelaxant Activity ◽  
Pyridazinone Derivatives

scholarly journals Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. I. 2-Phenylthiazolidine-3-thiocarboxamides.

1987 ◽  
Vol 35 (5) ◽  
pp. 1953-1968 ◽  
Author(s):  
HIROYUKI NATE ◽  
YASUO SEKINE ◽  
YASUSHI HONMA ◽  
HIDEO NAKAI ◽  
HIROSHI WADA ◽  
...  
Keyword(s):  
Cardiotonic Agents

ChemInform Abstract: Synthesis of 6-(1,4,5,6-Tetrahydro-6-oxo-3-pyridazinyl)-2H-1,4-benzoxazin-3(4H)ones as Possible Cardiotonic Agents.

ChemInform ◽  
1990 ◽  
Vol 21 (6) ◽  
Author(s):  
C. V. R. SASTRY ◽  
K. S. RAO ◽  
V. S. H. KRISHNAN ◽  
K. RASTOGI ◽  
M. L. JAIN ◽  
...  
Keyword(s):  
Cardiotonic Agents

ChemInform Abstract: An Efficient Synthesis of 4,5-Dihydro-3(2H)-pyridazinone Derivatives (IV)

ChemInform ◽  
2010 ◽  
Vol 28 (52) ◽  
pp. no-no
Author(s):  
G. TOTH ◽  
S. MOLNAR ◽  
T. TAMAS ◽  
I. BORBELY
Keyword(s):  
Efficient Synthesis ◽  
Pyridazinone Derivatives
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