scholarly journals Physicochemical Properties of Medicinal Agents. II. Relationship between Acid Dissociation Constants of Arylsulfonylurea Derivatives and the Hammett Equation

1973 ◽  
Vol 93 (12) ◽  
pp. 1647-1654 ◽  
Author(s):  
SHOZO ASADA ◽  
TATSUO NAKASATO ◽  
SADAKO TAKINO
Keyword(s):  
Physicochemical Properties ◽  
Dissociation Constants ◽  
Acid Dissociation ◽  
Hammett Equation ◽  
Acid Dissociation Constants

Synthesis and Tautomeric Structure of 2-arylazo-4H-imidazo[2,1-b][1,3,4]thiadiazines

2007 ◽  
Vol 2007 (8) ◽  
pp. 479-483 ◽  
Author(s):  
Ahmad S. Shawali ◽  
Mosselhi A.N. Mosselhi ◽  
Thoraya A. Farghaly
Keyword(s):  
Spectral Analysis ◽  
Dissociation Constants ◽  
Acid Dissociation ◽  
Hammett Equation ◽  
Acid Dissociation Constants ◽  
Hydrazone Form

Two series of the title compounds were prepared via reaction of N-aryl 2-oxohydrazonoyl halides with 1-amino-4-phenylimidazoline-2-thione. Their tautomeric structure was elucidated by spectral analysis, and the correlation of their acid dissociation constants with the Hammett equation, to be as the hydrazone form.

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