scholarly journals Ultracytochemical analysis of E-PTA-positive synaptic junction. Three cases of Down's syndrome together with Alzheimer-type dementia.

1992 ◽  
Vol 25 (1/2) ◽  
pp. 131-135
Author(s):  
KENICHIROU INOMATA ◽  
HIROAKI IGARASHI ◽  
Fumio NASU ◽  
MICHIYA SUGAHARA ◽  
YUKIO TAKASHIMA
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Synaptic Junction ◽  
Alzheimer Type Dementia

Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and down's syndrome

1983 ◽  
Vol 280 (1) ◽  
pp. 119-126 ◽  
Author(s):  
C.M. Yates ◽  
J. Simpson ◽  
A. Gordon ◽  
A.F.J. Maloney ◽  
Y. Allison ◽  
...  
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia

Chemokines and Pro-Inflammatory Cytokines in Down’s Syndrome: An Early Marker for Alzheimer-Type Dementia?

2002 ◽  
Vol 71 (4) ◽  
pp. 233-236 ◽  
Author(s):  
Mauro G. Carta ◽  
Paolo Serra ◽  
Assunta Ghiani ◽  
Elisabetta Manca ◽  
Maria Carolina Hardoy ◽  
...  
Keyword(s):  
Inflammatory Cytokines ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Early Marker ◽  
Alzheimer Type Dementia ◽  
Pro Inflammatory Cytokines

Up-regulation of E2F-1 in Down’s syndrome brain exhibiting neuropathological features of Alzheimer-type dementia

2001 ◽  
Vol 905 (1-2) ◽  
pp. 250-253 ◽  
Author(s):  
Kozo Motonaga ◽  
Masayuki Itoh ◽  
Aya Hirayama ◽  
Satoru Hirano ◽  
Laurence E Becker ◽  
...  
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia

Molecular mapping of alzheimer-type dementia in Down's syndrome

1998 ◽  
Vol 43 (3) ◽  
pp. 380-383 ◽  
Author(s):  
V. P. Prasher ◽  
Matthew J. Farrer ◽  
Anna M. Kessling ◽  
Elizabeth M. C. Fisher ◽  
R. J. West ◽  
...  
Keyword(s):  
Molecular Mapping ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia

Genetics, Ageing and Dementia

1984 ◽  
Vol 145 (1) ◽  
pp. 20-38 ◽  
Author(s):  
A. F. Wright ◽  
L. J. Whalley
Keyword(s):  
Age Of Onset ◽  
Down's Syndrome ◽  
Neuronal Cell ◽  
Down’S Syndrome ◽  
Cell Loss ◽  
Severe Form ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia ◽  
Number Of Patients ◽  
Relationship Of

SummaryThe contribution of genetic differences to variation in ageing and the relationship of ageing to certain types of dementia are discussed. Neuropathological changes commonly found in the ageing brain are present in more severe form in Alzheimer-type dementia, Down's syndrome, multi-infarct dementia, and a substantial number of patients with Parkinson's disease. An increased frequency of ageing-associated changes outside the brain have been reported in Alzheimer-type dementia, Down's syndrome, and multi-infarct dementia, although the evidence is generally meagre and in many cases requires further corroboration. Genetic studies of Alzheimer-type dementia support the existence of heterogeneity on the basis of family history and age of onset; early onset is associated with greater genetic risk and severity of abnormality. The increasing evidence of an association between DNA damage, premature ageing, and neuronal cell loss may provide insights into the aetiology of these and other forms of dementia.

Auditory P300 response in Down's syndrome: comparison with Alzheimer-type dementia and normal controls

1994 ◽  
Vol 1 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Ryusuke Kakigi ◽  
Ryuji Neshige ◽  
Yuki Matsuda ◽  
Yasuo Kuroda
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Auditory P300 ◽  
Alzheimer Type Dementia ◽  
Normal Controls

Erythrocyte membrane changes of individuals with Down's Syndrome in various stages of Alzheimer-type dementia

1993 ◽  
Vol 14 (3) ◽  
pp. 223-228 ◽  
Author(s):  
G.J.C.G.M. Bosman ◽  
F.E. Visser ◽  
A.J.M. de Man ◽  
I.G.P. Bartholomeus ◽  
W.J. de Grip
Keyword(s):  
Erythrocyte Membrane ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia ◽  
Membrane Changes
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