scholarly journals Antibacterial Activity and Bacterial Degradation of Linoleic Acid Hydroperoxide

1995 ◽  
Vol 14 (2) ◽  
pp. 67-74 ◽  
Author(s):  
Masako TSUCHIDA ◽  
Yoshiyuki MORISHITA
Keyword(s):  
Antibacterial Activity ◽  
Linoleic Acid ◽  
Bacterial Degradation ◽  
Linoleic Acid Hydroperoxide ◽  
Acid Hydroperoxide

scholarly journals Interaction between Mitochondrial Cytochromes and Linoleic Acid Hydroperoxide

1982 ◽  
Vol 69 (6) ◽  
pp. 1308-1314 ◽  
Author(s):  
Jacques Dupont ◽  
Pierre Rustin ◽  
Claude Lance
Keyword(s):  
Linoleic Acid ◽  
Linoleic Acid Hydroperoxide ◽  
Acid Hydroperoxide ◽  
Mitochondrial Cytochromes

scholarly journals Flavonoids Suppress the Cytotoxicity of Linoleic Acid Hydroperoxide toward PC12 Cells

2002 ◽  
Vol 25 (8) ◽  
pp. 1093-1096 ◽  
Author(s):  
Naoko Sasaki ◽  
Takeshi Toda ◽  
Takao Kaneko ◽  
Naomichi Baba ◽  
Mitsuyoshi Matsuo
Keyword(s):  
Linoleic Acid ◽  
Pc12 Cells ◽  
Linoleic Acid Hydroperoxide ◽  
Acid Hydroperoxide

Intracellular mechanisms for the decomposition of a lipid peroxide. II. Decomposition of a lipid peroxide by subcellular fractions

1969 ◽  
Vol 47 (5) ◽  
pp. 493-499 ◽  
Author(s):  
P. J. O'Brien ◽  
C. Little
Keyword(s):  
Linoleic Acid ◽  
Glutathione Peroxidase ◽  
Ph Dependence ◽  
Lipid Peroxide ◽  
Subcellular Fractions ◽  
Radical Mechanism ◽  
Complexing Agents ◽  
Linoleic Acid Hydroperoxide ◽  
Hydrogen Donors ◽  
Acid Hydroperoxide

The properties of subcellular fractions of rat liver in catalyzing the decomposition of linoleic acid hydroperoxide have been compared with those of transition salts, heme compounds, and nucleophiles. The properties compared included the range of products produced, the pH dependence of the reaction, and the effects of metal-complexing agents, inhibitors, and hydrogen donors. It was concluded that the decomposition of the hydroperoxide in the liver cell was due principally to reaction with the intracellular nucleophile glutathione by a mechanism catalyzed by the enzyme glutathione peroxidase. In the absence of glutathione, however, both the mitochondrial and microsomal fractions decomposed the hydroperoxide presumably by a radical mechanism probably involving the cytochromes.

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