scholarly journals Characterization of Albendazole-Randomly Methylated-β-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e113296 ◽  
Author(s):  
Agustina García ◽  
Darío Leonardi ◽  
María D. Vasconi ◽  
Lucila I. Hinrichsen ◽  
María C. Lamas
Keyword(s):  
Inclusion Complex ◽  
Murine Model ◽  
In Vivo Evaluation ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex

Erlotinib/hydroxypropyl-β-cyclodextrin inclusion complex: characterization and in vitro and in vivo evaluation

2015 ◽  
Vol 83 (3-4) ◽  
pp. 267-279 ◽  
Author(s):  
Sávio M. L. Gontijo ◽  
Pedro P. G. Guimarães ◽  
Celso T. R. Viana ◽  
Ângelo M. L. Denadai ◽  
Alinne D. M. Gomes ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
In Vivo Evaluation ◽  
Cyclodextrin Inclusion ◽  
Complex Characterization ◽  
Cyclodextrin Inclusion Complex

scholarly journals In Vitro and In Vivo Evaluation of Oxatomide β-Cyclodextrin Inclusion Complex

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Fahima M. Hashem ◽  
Mohamed Mostafa ◽  
Mahmoud Shaker ◽  
Mohamed Nasr
Keyword(s):  
Inclusion Complex ◽  
Drug Product ◽  
Water Soluble ◽  
In Vivo Evaluation ◽  
Water Soluble Polymers ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex ◽  
Dissolution Efficiency

The objective of this study was to evaluate the influence of oxatomide β-cyclodextrin inclusion complex on the physicochemical properties and bioavailability of the drug. Oxatomide β-cyclodextrin solid complex was prepared with equimolar ratio of both oxatomide and β-cyclodextrin in presence or absence of water soluble polymers using different techniques. The coevaporated complex prepared in presence of PVP-K15 showed a prompt drug release and significantly increased % dissolution efficiency compared to the pure oxatomide. Moreover, the results of bioavailability evaluation of this complex in rabbits compared to commercial drug product indicated a 73.15% increase in the oral bioavailability of oxatomide. In conclusion, inclusion complex of oxatomide with β-cyclodextrin prepared by coevaporation in presence of PVP-K15 not only results in an enhancement of the oxatomide dissolution rate but also improves the bioavailability of oxatomide.

In vitro and in vivo evaluation of a posaconazole-sulfobutyl ether-β -cyclodextrin inclusion complex

2018 ◽  
Vol 32 (12) ◽  
pp. e4364 ◽  
Author(s):  
Miao Wang ◽  
Juan Jiang ◽  
Yi Cai ◽  
Min Zhao ◽  
Qijuan Wu ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
In Vivo Evaluation ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex ◽  
Sulfobutyl Ether

scholarly journals Characterization of nimodipine/β-cyclodextrin inclusion complex

1998 ◽  
Vol 50 (S9) ◽  
pp. 180-180 ◽  
Author(s):  
Irena Homšek ◽  
Branko Kolarić ◽  
Slavica Ristić ◽  
Ivana Kolarić
Keyword(s):  
Inclusion Complex ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex

Characterization of a new TiF4 and β-cyclodextrin inclusion complex and its in vitro evaluation on inhibiting enamel demineralization

2013 ◽  
Vol 58 (3) ◽  
pp. 239-247 ◽  
Author(s):  
Camila Nassur ◽  
Adílis Kalina Alexandria ◽  
Luciana Pomarico ◽  
Valeria Pereira de Sousa ◽  
Lúcio Mendes Cabral ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
In Vitro Evaluation ◽  
Enamel Demineralization ◽  
Cyclodextrin Inclusion ◽  
Cyclodextrin Inclusion Complex
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