Echocardiographic Diagnosis of Thrombus on a Heterograft Aortic Valve in the Mitral Position

The Carpentier-Edwards supra-annular porcine bioprosthesis (second generation prosthesis) was implanted in 2438 patients in 2482 operations between 1982 and 1992. The mean age of the population was 64 years with a range from 21 years to 89 years. There were 1334 aortic and 934 mitral valve replacements. The population was divided into five groups: 21 to 40 years (n = 132); 41 to 50 years (n = 189); 51 to 60 years (n = 454); 61 to 70 years (n = 849); and over 70 years (n = 858). There was no difference in sunival by valve position for age groups 21 to 40 years and 41 to 50 years. Sunival within the age groups 51 to 60 years, 61 to 70 years, and over 70 years was greater for patients with aortic compared with mitral and multiple valve replacements. The freedom from structural valve deterioration at 10 years for all age groups was highest for valves in the aortic position. Patients with valves in the mitral position had a higher freedom from structural valve deterioration at 10 years than those who had multiple valve replacement, although not all the differences were significant. There was a lower incidence of structural valve deterioration in the older age groups. We concluded that the use of the Carpentier-Edwards supra-annular porcine bioprosthesis for aortic valve replacement can be extended to patients over 60 years of age, while its use for mitral valve replacement can be extended to those above 70 years of age.

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Antithrombin III and Platelet Volume in Correlation with Hemolysis after Valve Replacements Using Xenografts.

10.1055/s-0039-1684442 ◽

1979 ◽

Author(s):

I. Volkmer ◽

Kh. Nienhaus ◽

E. Wenzel ◽

H. Jäger ◽

J. Welsch ◽

...

Keyword(s):

Aortic Valve ◽

Valve Replacement ◽

Plasma Proteins ◽

Heart Valves ◽

Antithrombin Iii ◽

Volume Distribution ◽

Platelet Volume ◽

Clinical Investigations ◽

Mitral Position ◽

Artificial Heart Valves

Blood corpuscles as well as plasma proteins are traumatized, when blood comes in contact with surfaces of artificial heart valves. 30 patients who had received valve replacement (N = 18, Edwards Xenografts in aortic position; N = 12, Hancock Xenografts in mitral position) in addition to the parameters for hemolysis (haptoglobin, LDH, erythrocyte count, hemoglobin), platelet count, platelet volume distribution (Coulter Counter equipment) and coagulation parameters (PTT, PTZ, fibrinogen, plasmathrombin- and thrombincoagulase times, thrombelastography) were controlled. Antithrombin III was evaluated immunologically (Mancini) and photometrically (Chromozym TH). Laboratory and clinical investigations were performed postoperatively after 6 weeks and thereafter every 3 months (19.5 months). A significant higher rate of hemolysis was observed in patients with an aortic valve replacement. Antithrombin III was found to be significantly decreased, especially in patients with aortic valve replacements. A significant and comparable increase in small platelets (< 4.3 μ3) was observed in both patients’ groups.

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TCT-709 Feasibility of Transapical Implantation of Transcatheter Aortic Valve in the Mitral Position Using a Novel Valve Retention System

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2015.08.729 ◽

2015 ◽

Vol 66 (15) ◽

pp. B289-B290

Author(s):

Yanping Cheng ◽

Torsten P. Vahl ◽

Gerard B. Conditt ◽

Adrienne D. Meyers ◽

Karl Van Wygerden ◽

...

Keyword(s):

Aortic Valve ◽

Transcatheter Aortic Valve ◽

Mitral Position ◽

Retention System

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Edwards Inspiris Resilia® valve for mitral replacement in an infant after mechanical valve failure

Cardiology in the Young ◽

10.1017/s1047951118001816 ◽

2018 ◽

Vol 29 (2) ◽

pp. 219-221 ◽

Cited By ~ 1

Author(s):

Radoslaw Jaworski ◽

Andrzej Kansy ◽

Mariusz Birbach ◽

Anna Brodzikowska-Pytel ◽

Monika Kowalczyk-Domagala ◽

...

Keyword(s):

Coronary Artery ◽

Mitral Valve ◽

Aortic Valve ◽

Pulmonary Artery ◽

Oral Anticoagulation ◽

Left Coronary Artery ◽

Mechanical Valve ◽

Heparin Infusion ◽

Mitral Position ◽

Surgical Implantation

AbstractWe present the surgical implantation of the Edwards Inspiris Resilia® aortic valve in mitral position for mechanical mitral valve failure in a severely ill infant after valve replacement because of anomalous origin of the left coronary artery from the pulmonary artery. The biological valve was chosen because the child could not receive oral anticoagulation and was for several months on heparin infusion. The procedure was safely performed with good haemodynamic result.

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