Background:
Heart transplantation remains the treatment of choice for end-stage heart failure patients, owing to
the associated dual improvements in quality of life, and prognosis. The discrepancy between higher demand and supply of
donor organs is the limiting factor, and is established universally. Increasing consideration of donor population up to 65
years of age and marginal donor hearts has helped to facilitate the availability of potential grafts. However, grafts from older
donors carry the mid-term increased risk of coronary allograft vasculopathy, including donor transmitted coronary disease.
Case report:
A 15-year-old female underwent orthotopic heart transplantation for non-ischaemic cardiomyopathy, the donor
was a 44-year-old male. The recipient developed anterior wall ischaemia within a year requiring coronary angioplasty and
stent implantation to treat the severe obstruction in the left anterior descending coronary artery. However, two months later,
the patient was readmitted with in-stent restenosis.
Therefore, to optimally revascularise the left anterior descending coronary artery, and minimise risks associated with resternotomy,
a minimally invasive direct coronary artery bypass grafting of the left internal mammary artery to left anterior
descending artery was performed.
Conclusion:
Surgical revascularisation in generalised CAV is an inadequate option; repeat HTx is the treatment of choice,
albeit given its morbidity should be reserved for a highly selected patient population. In localised coronary lesions,
conventional coronary bypass surgery may be a feasible choice in selected patients with LAD lesions. Minimal invasive
techniques, such as MIDCAB rather than robotic techniques, would be preferable for ease of approach and to limit the
surgical re-do trauma.