Ocular hypertelorism, facial basal cell carcinomas, and multiple odontogenic keratocysts of the jaws

1988 ◽  
Vol 116 (7) ◽  
pp. 887-889 ◽  
Author(s):  
Arthur H. Friedlander ◽  
Eugenio G. Herbosa ◽  
James R. Peoples
Keyword(s):  
Basal Cell ◽  
Odontogenic Keratocysts ◽  
Basal Cell Carcinomas ◽  
Ocular Hypertelorism

Expression of calretinin in odontogenic keratocysts and basal cell carcinomas: A study of sporadic and Gorlin-Goltz syndrome-related cases

2020 ◽  
Vol 45 ◽  
pp. 151472
Author(s):  
Anna Maria Cesinaro ◽  
Giammarco Burtini ◽  
Antonino Maiorana ◽  
Giulio Rossi ◽  
Mario Migaldi
Keyword(s):  
Basal Cell ◽  
Odontogenic Keratocysts ◽  
Goltz Syndrome ◽  
Basal Cell Carcinomas

Immunolocalization of PTCH Protein in Odontogenic Cysts and Tumors

2002 ◽  
Vol 81 (11) ◽  
pp. 757-760 ◽  
Author(s):  
D.C. Barreto ◽  
A.E. Bale ◽  
L. De Marco ◽  
R.S. Gomez
Keyword(s):  
Basal Cell ◽  
Tumor Suppression ◽  
Protein Product ◽  
Odontogenic Tumors ◽  
Odontogenic Cysts ◽  
Odontogenic Keratocysts ◽  
Basal Cell Carcinomas ◽  
Different Types ◽  
Embryologic Development

The human patched gene ( PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic lesions by immunohistochemistry, and compared their PTCH expression with that in basal cell carcinomas. All odontogenic lesions, including two keratocysts with truncating mutations, were positive for PTCH. Different types of lesions had different amounts of staining. Lack of staining was noted in the majority of basal cell carcinomas. Taken together, these data suggest that odontogenic keratocysts arise with heterozygous mutations of the PTCH gene.

Expression of the Sonic Hedgehog receptor ‘PATCHED’ in basal cell carcinomas and odontogenic keratocysts

2001 ◽  
Vol 194 (4) ◽  
pp. 473-477 ◽  
Author(s):  
W. Zedan ◽  
P. A. Robinson ◽  
A. F. Markham ◽  
A. S. High
Keyword(s):  
Sonic Hedgehog ◽  
Basal Cell ◽  
Odontogenic Keratocysts ◽  
Basal Cell Carcinomas

Scalpel excision of basal cell carcinomas

1978 ◽  
Vol 114 (5) ◽  
pp. 739-742 ◽  
Author(s):  
R. S. Bart
Keyword(s):  
Basal Cell ◽  
Basal Cell Carcinomas

Follicular atrophoderma with multiple basal cell carcinomas. An abortive form of bazex syndrome.

1989 ◽  
Vol 51 (2) ◽  
pp. 250-255
Author(s):  
Seiji ARASE ◽  
Hideki NAKANISHI ◽  
Shin HARADA ◽  
Fumio SHIGEMI ◽  
Katsuyuki TAKEDA
Keyword(s):  
Basal Cell ◽  
Basal Cell Carcinomas ◽  
Multiple Basal Cell Carcinomas
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