scholarly journals Study on Change in Retinal Nerve Fibre Layer (RNFL) Thickness Using Optical Coherence Tomography (Spectral Domain OCT) after Trabeculectomy in Adult Patients with Glaucoma

2019 ◽  
Vol 8 (45) ◽  
pp. 3392-3396
Author(s):  
Thakur S
2010 ◽  
Vol 04 (01) ◽  
pp. 17
Author(s):  
Antonio Ferreras ◽  
Luis E Pablo ◽  
◽  

Evaluation of the retinal nerve fibre layer (RNFL) is key to diagnosing and monitoring changes in glaucoma. Optical coherence tomography (OCT) is a non-invasive, objective, quantitative method that provides realtimein vivoimages of the retina. The new spectral-domain OCTs have increased resolution and acquisition speed compared with earlier time-domain OCTs, enabling the generation of highly detailed 3D images. Axial resolution has also been improved from 10 to 3–5μm. Thus, spectral-domain OCT is a promising new clinical tool for evaluating the RNFL in glaucoma and other retinal diseases. Recent studies report that spectral-domain OCT provides peri-papillary RNFL measurements with excellent repeatability and reproducibility. The reduced variability compared with time-domain OCT may improve detection of disease progression in glaucoma patients. In cross-sectional studies, most authors suggest that the two OCT systems have similar diagnostic potential to discriminate between healthy and glaucoma patients. Nevertheless, the Cirrus HD-OCT (spectral-domain) tends to yield a slightly higher sensitivity at fixed specificities than the Stratus OCT (time-domain) for glaucoma diagnosis. In healthy subjects and patients with glaucoma, RNFL thickness measurements acquired with the two OCT systems correlated well, but their values cannot be used interchangeably.


Sign in / Sign up

Export Citation Format

Share Document