Diagnostic Yield of Colonoscopy in Patients Referred with Iron Deficiency Anaemia. Do Patients under 50 Years of Age Merit Such Indication?

2007 ◽  
Vol 102 ◽  
pp. S266
Author(s):  
Mahboob Ali ◽  
Linga Devi Thanasekaran ◽  
Abdur Rafeh Khan ◽  
Irfan Maqsood ◽  
Nosheen Khawaja ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Diagnostic Yield ◽  
Deficiency Anaemia

scholarly journals Video Capsule endoscopy in patients with Iron Deficiency Anaemia: Experience at a Regional Australian Service

2021 ◽  
Author(s):  
Maddison Furner ◽  
Robyn Nagel ◽  
Janani Pinidiyapathirage
Keyword(s):  
Iron Deficiency ◽  
Capsule Endoscopy ◽  
Iron Deficiency Anaemia ◽  
Diagnostic Yield ◽  
Video Capsule Endoscopy ◽  
Positive Finding ◽  
Diagnostic Modality ◽  
Deficiency Anaemia ◽  
Frequent Finding ◽  
Regional Australia

Abstract Background Few studies have examined the diagnostic yield of video capsule endoscopy (VCE) in patients with iron deficiency anaemia (IDA). This retrospective study aims to identify the yield of VCE, distribution of VCE findings in IDA and factors predictive of positive findings among patients presenting to a gasteroendoscopy practice in regional Australia. Methods Findings of consecutive VCE studies between March 2017 and April 2020 performed in patients with unexplained IDA and negative conventional endoscopy were included in this retrospective analysis. All endoscopies were performed and reported by a single specialist physician. Relevant clinical data including demographics, medication use, haemoglobin and ferritin levels were extracted into a standardised spreadsheet with procedural findings. A positive diagnostic yield was considered when VCE diagnosed one or more lesions that could explain the IDA. Statistical analysis was used to determine variables correlated with definite VCE findings. Results In total 123 procedures were included. Mean age of the patients was 67.9 years. Mean haemoglobin and ferritin levels were 93.3 g/L and 11.9ug/L, respectively. Positive findings were present in 54.5% of patients with the most frequent finding being angiodysplasia (52.2%). Haemoglobin level was the only variable associated with a positive finding. A significant number of studies had significant findings outside the small bowel (41.8%), overwhelmingly within reach of conventional upper endoscopy (89.3%). Conclusions VCE is a valuable diagnostic modality in patients with IDA. Low haemoglobin was associated with a positive finding on VCE in this group of patients.

scholarly journals The dedicated iron deficiency anaemia clinic: a 15-year experience

2020 ◽  
pp. flgastro-2020-101470
Author(s):  
Helen Stone ◽  
Orouba Almilaji ◽  
Christopher John ◽  
Carla Smith ◽  
Susan L Surgenor ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Diagnostic Yield ◽  
Referral Rate ◽  
Gi Tract ◽  
Right Colon ◽  
Deficiency Anaemia ◽  
Study Population ◽  
The Right ◽  
Cumulative Experience

ObjectiveTo report our cumulative experience from a dedicated iron deficiency anaemia (IDA) clinic over the last 15 years—with particular emphasis on referral rate, uptake of investigation, impact on endoscopy services, diagnostic yield of gastrointestinal (GI) investigation and the issue of recurrent IDA.MethodA series of analyses of a register of 2808 referrals to the Poole IDA clinic between 2004 and 2018.ResultsThe study population of 2808 had a sex ratio of 1.9 (female/male ratio) and a median age of 72 years (IQR: 60–79). A rising referral rate over the study period appears to be plateauing at around 2 cases per 1000 population per annum. On the basis of a snapshot audit, investigation of IDA may now account for over 20% of all diagnostic endoscopies.Overall, 86% of cases underwent examination of the upper and lower GI tract. Significant GI pathology was identified in 27% of the investigated cohort. Adenocarcinoma of the upper or lower GI tract was found in 8.3%, the majority in the right colon. The prevalence of recurrent IDA was estimated at 12.4%, and the results of investigation of this subgroup are reported.ConclusionUnexplained IDA is common, particularly in those over 60 years, and may be the first indication of underlying GI malignancy in over 8% of cases. Unresolved challenges include accommodating the resulting endoscopy workload, establishing a risk/benefit ratio for investigating those with major comorbidities and the management of recurrent IDA.

Tu1341 Low Long Term Predictive Value of Sbce Despite High Diagnostic Yield in Iron Deficiency Anaemia

2012 ◽  
Vol 142 (5) ◽  
pp. S-807
Author(s):  
Grainne Holleran ◽  
Sarah Barry ◽  
Orla Thornton ◽  
Mark Dobson ◽  
Deirdre McNamara
Keyword(s):  
Iron Deficiency ◽  
Predictive Value ◽  
Iron Deficiency Anaemia ◽  
Diagnostic Yield ◽  
Deficiency Anaemia ◽  
High Diagnostic Yield

scholarly journals Diagnostic yield of push-type enteroscopy in relation to indication

Gut ◽  
1998 ◽  
Vol 42 (3) ◽  
pp. 421-425 ◽  
Author(s):  
B Landi ◽  
M Tkoub ◽  
M Gaudric ◽  
R Guimbaud ◽  
J P Cervoni ◽  
...  
Keyword(s):  
Small Intestine ◽  
Abdominal Pain ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Diagnostic Yield ◽  
Diagnostic Value ◽  
Chronic Diarrhoea ◽  
Deficiency Anaemia ◽  
Digestive Haemorrhage ◽  
N 93

Background—Push-type enteroscopy, a recent method for investigating the small intestine, is currently undergoing assessment. Its diagnostic yield varies in the studies reported to date.Aim—To assess the diagnostic value of push-type enteroscopy according to indication.Patients and methods—From January 1994 to September 1995, 152 consecutive patients (mean age 34 years) underwent push-type enteroscopy (jejunoscopy, n=93; retrograde ileoscopy, n=17; and double way enteroscopy, n=42). The indications were: unexplained iron deficiency anaemia or macroscopic gastrointestinal bleeding (n=76), radiological abnormalities of the small intestine (n=23), chronic diarrhoea and/or malabsorption syndrome (n=18), abdominal pain (n=12), and miscellaneous (n=23). All patients had undergone previous negative aetiological investigations.Results—The jejunum and ileum were explored through 120 cm (30–160 cm) and 60 cm (20–120 cm). Digestive bleeding: lesions of the small bowel were found in 6% of the patients with isolated iron deficiency anaemia and 20% of patients with patent digestive haemorrhage. Radiological abnormalities of the small intestine: push-type enteroscopy provided a diagnosis or modified the interpretation of radiological findings in 18/23 cases (78%). Chronic diarrhoea and/or malabsorption: push-type enteroscopy yielded explanatory findings in four cases (22%). Abdominal pain: push-type enteroscopy provided no diagnosis.Conclusion—In this series, push-type enteroscopy was of particular value in investigating patients with radiological abnormalities of the small intestine. It was of some value in the exploration of patent digestive haemorrhage or chronic diarrhoea, but not of abdominal pain. Its value was limited in the exploration of iron deficiency anaemia.

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