Under Pressure: Obscure Bleeding due to Small Bowel Varices

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S1149-S1150
Author(s):  
Nicole Harrison ◽  
Sarah Davis ◽  
Lawrence Goldkind
2019 ◽  
Vol 16 (1) ◽  
pp. 62-71
Author(s):  
Natasha Harris ◽  
Alaa Rostom ◽  
Husein Moloo

Background:  Obscure gastrointestinal bleeding from idiopathic small bowel varices is both a diagnostic and management challenge for physicians. There are very few cases reported in the literature and there is no consensus on management recommendations. Aims:  To present the case of a 34-year-old male patient with bleeding from idiopathic jejunal varices and to review similar cases in the literature.  Methods:  A case of idiopathic jejunal varices is reported. A literature review was conducted and a total of 24 articles describing idiopathic small bowel varices were identified. Results:  Case Report: A 34-year-old gentleman was referred for worsening obscure gastrointestinal bleeding and anemia. Anterograde single balloon enteroscopy revealed several petechial like lesions that were not classic for angiodysplasia. These lesions were initially treated with argon plasma coagulation and clipped, which did not resolve the patient’s persistent anemia. No venous abnormalities were identified on computed tomography of the abdomen and pelvis with contrast. The patient underwent an endoscopically assisted exploratory laparoscopy that was converted to a laparotomy upon finding of grossly abnormal distal jejunum. Dilated and tortuous varicosities were identified involving approximately 150 cm of small bowel. It was decided to resect the 40 cm segment of jejunum in which varices were visible endoscopically. There was no evidence of thrombosis in the resected specimen. The patient suffered a pulmonary embolism post-operatively, believed to be provoked by the surgery.  The patient has had no re-bleeding 12 months post-resection. Literature Review: Both familial and non-familial accounts of small bowel varices in the absence of a primary cause have been reported in the literature. When supportive therapy is insufficient, the most common treatment modality chosen is surgical resection. Select cases have also demonstrated that sclerotherapy and varix dissection can be used for to treat these lesions. Conclusions:  Idiopathic small bowel varices pose both diagnostic and therapeutic challenges for physicians. In the literature, several treatment modalities have been shown to be successful; these include surgical resection, varix dissection and sclerotherapy. There is no consensus on the preferred treatment strategy. This report demonstrates endoscopically assisted surgical resection as a viable management strategy for bleeding of idiopathic small bowel varices, an uncommon cause of occult GI bleeding.


2020 ◽  
Vol 115 (1) ◽  
pp. S1149-S1150
Author(s):  
Pankaj Aggarwal ◽  
Harsh Patel ◽  
Randy Wright

1986 ◽  
Vol 11 (1) ◽  
pp. 183-184 ◽  
Author(s):  
D. Randall Radin ◽  
Barry N. Siskind ◽  
Seymour Alpert ◽  
Robert G. Bernstein

2008 ◽  
Vol 67 (5) ◽  
pp. AB258
Author(s):  
John Staples ◽  
Mark Mcloughlin ◽  
Pardis Lakzadeh ◽  
Iman Zandieh ◽  
Jaber Al Ali ◽  
...  

2005 ◽  
Vol 62 (1) ◽  
pp. 166-169 ◽  
Author(s):  
Stephan Hellmig ◽  
Markus Seeger ◽  
Eckhard Stüber ◽  
Karlheinz Kiehne ◽  
Stefan Schreiber ◽  
...  

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1313
Author(s):  
Alessia Todeschini ◽  
Ilaria Loconte ◽  
Antonella Contaldo ◽  
Enzo Ierardi ◽  
Alfredo Di Leo ◽  
...  

A 80-year-old woman underwent vulvar melanoma resection and segmental lung resection for pulmonary metastasis. Immunotherapy with Nivolumab was performed. One year later, the patient was admitted for gastrointestinal (GI) recurrent bleeding and severe anemia. Esophagoastroduodenoscopy and colonoscopy did not show any abnormality, while videocapsule endoscopy (VCE) revealed an irregular and exophytic whitish area with a “coal-black” central depression. Small bowel resection was performed and histological examination revealed S100 protein strongly positive melanoma metastasis. The patient died six months later from disease progression. A “coal-black” appearance of intestinal metastatic melanoma has been described only twice before this report. In one case the patient had been treated by immunotherapy with interferon A and dendritic cell-based vaccination. In our patient, it is presumable that the picture we observed was a consequence of Nivolumab treatment inducing the disappearance of melanocytes in the area surrounding the metastasis with the onset of the central coal-black lesion encircled by whitish tissue. This picture should be emblematic of intestinal metastatic melanoma in subjects treated with immunotherapy showing occult/obscure bleeding.


2016 ◽  
Vol 8 (16) ◽  
pp. 568 ◽  
Author(s):  
Grainne Holleran ◽  
Mary Hussey ◽  
Deirdre McNamara
Keyword(s):  

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