scholarly journals Shared Transethnic Genetic Basis Between Panic Disorder and Psychiatric and Intermediate Phenotypes

2021 ◽  
Vol 13 (1) ◽  
pp. 2-12
Author(s):  
Kazutaka Ohi ◽  
Takeshi Otowa ◽  
Mihoko Shimada ◽  
Shunsuke Sugiyama ◽  
Shunsuke Tanahashi ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Genetic Basis ◽  
Intermediate Phenotypes

Shared transethnic genetic basis of panic disorder and psychiatric and related intermediate phenotypes

2021 ◽  
Vol 42 ◽  
pp. 87-96
Author(s):  
Kazutaka Ohi ◽  
Takeshi Otowa ◽  
Mihoko Shimada ◽  
Shunsuke Sugiyama ◽  
Yukimasa Muto ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Genetic Basis ◽  
Intermediate Phenotypes

Genetic basis of predisposition to panic disorder

2012 ◽  
Vol 2 (4) ◽  
pp. 294-305 ◽  
Author(s):  
L. A. Korobeynikova ◽  
O. I. Rudko ◽  
Yu. E. Azimova ◽  
N. M. Fokina ◽  
E. A. Klimov
Keyword(s):  
Panic Disorder ◽  
Genetic Basis

scholarly journals Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Michael G. Gottschalk ◽  
Jan Richter ◽  
Christiane Ziegler ◽  
Miriam A. Schiele ◽  
Julia Mann ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Treatment Response ◽  
Intermediate Phenotypes

RGS2genetic variation: Association analysis with panic disorder and dimensional as well as intermediate phenotypes of anxiety

2015 ◽  
Vol 168 (3) ◽  
pp. 211-222 ◽  
Author(s):  
Christa Hohoff ◽  
Heike Weber ◽  
Jan Richter ◽  
Katharina Domschke ◽  
Peter M. Zwanzger ◽  
...  
Keyword(s):  
Panic Disorder ◽  
Association Analysis ◽  
Intermediate Phenotypes

scholarly journals The Genetic Basis of Panic Disorder

2011 ◽  
Vol 26 (6) ◽  
pp. 701 ◽  
Author(s):  
Hae-Ran Na ◽  
Eun-Ho Kang ◽  
Jae-Hon Lee ◽  
Bum-Hee Yu
Keyword(s):  
Panic Disorder ◽  
Genetic Basis

Identifying Patterns in Complex Field Data

2017 ◽  
Vol 225 (3) ◽  
pp. 268-284 ◽  
Author(s):  
Andrew J. White ◽  
Dieter Kleinböhl ◽  
Thomas Lang ◽  
Alfons O. Hamm ◽  
Alexander L. Gerlach ◽  
...  
Keyword(s):  
Heart Rate ◽  
Panic Disorder ◽  
Latent Class ◽  
Treatment Protocol ◽  
Situational Factors ◽  
Self Report ◽  
Complex Field ◽  
Cluster Assignment ◽  
Experimental Conditions ◽  
Conventional Analysis

Abstract. Ambulatory assessment methods are well suited to examine how patients with panic disorder and agoraphobia (PD/A) undertake situational exposure. But under complex field conditions of a complex treatment protocol, the variability of data can be so high that conventional analytic approaches based on group averages inadequately describe individual variability. To understand how fear responses change throughout exposure, we aimed to demonstrate the incremental value of sorting HR responses (an index of fear) prior to applying averaging procedures. As part of their panic treatment, 85 patients with PD/A completed a total of 233 bus exposure exercises. Heart rate (HR), global positioning system (GPS) location, and self-report data were collected. Patients were randomized to one of two active treatment conditions (standard exposure or fear-augmented exposure) and completed multiple exposures in four consecutive exposure sessions. We used latent class cluster analysis (CA) to cluster heart rate (HR) responses collected at the start of bus exposure exercises (5 min long, centered on bus boarding). Intra-individual patterns of assignment across exposure repetitions were examined to explore the relative influence of individual and situational factors on HR responses. The association between response types and panic disorder symptoms was determined by examining how clusters were related to self-reported anxiety, concordance between HR and self-report measures, and bodily symptom tolerance. These analyses were contrasted with a conventional analysis based on averages across experimental conditions. HR responses were sorted according to form and level criteria and yielded nine clusters, seven of which were interpretable. Cluster assignment was not stable across sessions or treatment condition. Clusters characterized by a low absolute HR level that slowly decayed corresponded with low self-reported anxiety and greater self-rated tolerance of bodily symptoms. Inconsistent individual factors influenced HR responses less than situational factors. Applying clustering can help to extend the conventional analysis of highly variable data collected in the field. We discuss the merits of this approach and reasons for the non-stereotypical pattern of cluster assignment across exposures.

The Facts About Panic Disorder: The Facts

PsycCRITIQUES ◽  
2005 ◽  
Vol 50 (2) ◽  
Author(s):  
Christine Karper
Keyword(s):  
Panic Disorder

Patient dropout from a couples' group treatment for panic disorder with agoraphobia.

1995 ◽  
Vol 26 (6) ◽  
pp. 626-628 ◽  
Author(s):  
Michele M. Carter ◽  
Julia Turovsky ◽  
Tracy Sbrocco ◽  
Elizabeth A. Meadows ◽  
David H. Barlow
Keyword(s):  
Panic Disorder ◽  
Group Treatment ◽  
Patient Dropout

Blood-Injury Phobia Predicts Nonresponsiveness to Pharmacotherapy for Panic Disorder

2004 ◽  
Author(s):  
T. Overbeek ◽  
H. Buchold ◽  
K. Schruers ◽  
E. Griez
Keyword(s):  
Panic Disorder
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