Double-blind placebo-controlled study of bepotastine besilate in pediatric patients with perennial allergic rhinitis

2015 ◽  
Vol 16 (16) ◽  
pp. 2395-2408 ◽  
Author(s):  
Kimihiro Okubo ◽  
Masahiko Ichimura ◽  
Tomoya Koyama ◽  
Yutaka Susuta ◽  
Hitoshi Izaki
Keyword(s):  
Allergic Rhinitis ◽  
Pediatric Patients ◽  
Controlled Study ◽  
Perennial Allergic Rhinitis ◽  
Double Blind ◽  
Double Blind Placebo

Randomized, double-blind, placebo-controlled study of montelukast for treating perennial allergic rhinitis

2005 ◽  
Vol 95 (6) ◽  
pp. 551-557 ◽  
Author(s):  
Piyush Patel ◽  
George Philip ◽  
William Yang ◽  
Robert Call ◽  
Friedrich Horak ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Controlled Study ◽  
Perennial Allergic Rhinitis ◽  
Double Blind ◽  
Double Blind Placebo

Nasal Immunotherapy is Effective in the Treatment of Rhinitis Due to Mite Allergy. A Double Blind Placebo-Controlled Study with Rhinological Evaluations

2002 ◽  
Vol 15 (2) ◽  
pp. 141-147 ◽  
Author(s):  
D. Passàli ◽  
L. Bellussi ◽  
G.C. Passàli ◽  
F. M. Passàli
Keyword(s):  
Allergic Rhinitis ◽  
Mucociliary Clearance ◽  
Controlled Trial ◽  
Controlled Study ◽  
Perennial Allergic Rhinitis ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Nasal Provocation ◽  
Mite Allergy ◽  
Perennial Rhinitis

The aim of this paper is to evaluate the efficacy of intranasal hyposensitizing therapy in perennial rhinitis. 36 patients suffering from perennial allergic rhinitis (Dermatophagoides-sensitive) underwent a double blind placebo-controlled trial for a period of 8 months. The efficacy of nasal immunotherapy was evaluated by collecting symptoms score and evaluating objective rhinological parameters (nasal resistance, cross areas and volumes, mucociliary clearance times, specific nasal provocation threshold). A significant improvement (p0,01) of symptom score of active against placebo group was observed after treatment. Also objective nasal parameters (total nasal resistances, mucociliary clearance, C-notch area, and provocative threshold) significantly (p0,01) improved after treatment. Adverse local reactions were rare and did not interfere with the protocol. The results underline the efficacy and quickness of local nasal immunotherapy in the treatment of perennial allergic rhinitis documented by the improvement of subjective and objective parameters.

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