scholarly journals Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain

2011 ◽  
Vol 31 (7) ◽  
pp. 2615-2623 ◽  
Author(s):  
A. Gadadhar ◽  
R. Marr ◽  
O. Lazarov
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Adult Brain ◽  
Presenilin 1

scholarly journals Author Correction: Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Chun-Ping Cui ◽  
Yuan Zhang ◽  
Chanjuan Wang ◽  
Fang Yuan ◽  
Hongchang Li ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor

scholarly journals miR-34a modulates neural progenitor cell differentiation

2008 ◽  
Vol 319 (2) ◽  
pp. 535
Author(s):  
Sarah K. Fineberg ◽  
Laboni L. Ghosh ◽  
B.J. He ◽  
Scott Q. Harper ◽  
Beverly L. Davidson
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor

scholarly journals NFIX Regulates Neural Progenitor Cell Differentiation During Hippocampal Morphogenesis

2012 ◽  
Vol 24 (1) ◽  
pp. 261-279 ◽  
Author(s):  
Yee Hsieh Evelyn Heng ◽  
Robert C. McLeay ◽  
Tracey J. Harvey ◽  
Aaron G. Smith ◽  
Guy Barry ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor

scholarly journals Quantitative and kinetic profile of Wnt/β-catenin signaling components during human neural progenitor cell differentiation

2011 ◽  
Vol 16 (4) ◽  
Author(s):  
Orianne Mazemondet ◽  
Rayk Hubner ◽  
Jana Frahm ◽  
Dirk Koczan ◽  
Benjamin Bader ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Target Genes ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Signaling Molecules ◽  
Human Neural Progenitor Cell ◽  
Wnt Ligands ◽  
Spatio Temporal

AbstractReNcell VM is an immortalized human neural progenitor cell line with the ability to differentiate in vitro into astrocytes and neurons, in which the Wnt/β-catenin pathway is known to be involved. However, little is known about kinetic changes of this pathway in human neural progenitor cell differentiation. In the present study, we provide a quantitative profile of Wnt/β-catenin pathway dynamics showing its spatio-temporal regulation during ReNcell VM cell differentiation. We show first that T-cell factor dependent transcription can be activated by stabilized β-catenin. Furthermore, endogenous Wnt ligands, pathway receptors and signaling molecules are temporally controlled, demonstrating changes related to differentiation stages. During the first three hours of differentiation the signaling molecules LRP6, Dvl2 and β-catenin are spatio-temporally regulated between distinct cellular compartments. From 24 h onward, components of the Wnt/β-catenin pathway are strongly activated and regulated as shown by mRNA up-regulation of Wnt ligands (Wnt5a and Wnt7a), receptors including Frizzled-2, -3, -6, -7, and -9, and co-receptors, and target genes including Axin2. This detailed temporal profile of the Wnt/β-catenin pathway is a first step to understand, control and to orientate, in vitro, human neural progenitor cell differentiation.

scholarly journals NB-3/Notch1 Pathway via Deltex1 Promotes Neural Progenitor Cell Differentiation into Oligodendrocytes

2004 ◽  
Vol 279 (24) ◽  
pp. 25858-25865 ◽  
Author(s):  
Xiao-Ying Cui ◽  
Qi-Dong Hu ◽  
Meriem Tekaya ◽  
Yasushi Shimoda ◽  
Beng-Ti Ang ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor

scholarly journals PCDH19 regulation of neural progenitor cell differentiation suggests asynchrony of neurogenesis as a mechanism contributing to PCDH19 Girls Clustering Epilepsy

2018 ◽  
Vol 116 ◽  
pp. 106-119 ◽  
Author(s):  
Claire C. Homan ◽  
Stephen Pederson ◽  
Thu-Hien To ◽  
Chuan Tan ◽  
Sandra Piltz ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor

scholarly journals Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Chun-Ping Cui ◽  
Yuan Zhang ◽  
Chanjuan Wang ◽  
Fang Yuan ◽  
Hongchang Li ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor
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