scholarly journals Initial experience in direct graft perfusion assessment following orthotopic liver transplant

Author(s):  
A. V. Moiseenko ◽  
A. A. Polikarpov ◽  
P. G. Tarazov ◽  
D. A. Granov

Objective: classical methods of determining arterial blood supply of the graft following orthotopic liver transplantation (OLT) reflect the presence of blood flow in the trunk and large branches of the A. hepatica, without the characteristic of completeness of blood filling of peripheral sections, which is very important for objective evaluation of function. The aim of this study is to establish the diagnostic value of a direct perfusion study (IFlow) of the graft. Materials and methods. From 1998 to 2019, 245 OLTs were conducted. From 2015 to 2019, arterial changes were detected in 24 (23%) patients after 104 OLTs. A perfusion study was performed in 9 patients with suspected arterial graft failure. According to the IFlow study, liver hypoperfusion due to stenosis and/or splenic steal syndrome was detected in 8 cases and became an indication for therapeutic intervention. Results. Hepatic stenting and/or splenic artery embolization was performed to improve arterial blood supply to the liver. Endovascular procedures performed restored the perfusion index from 0.24 (0.01–0.89) to 0.61 (0.35–0.98). Conclusion. Absence of ultrasound and multispiral computed tomography signs of arterial complications does not rule out the need for perfusion angiography. Perfusion angiography allows to objectify the angiography data and perform corrective intervention in good time.

Author(s):  
B. B. Gegenava ◽  
S. A. Kurnosov ◽  
Ya. G. Moysyuk ◽  
N. N. Vetsheva ◽  
A. A. Ammosov

Introduction. Liver transplantation is considered the most effective treatment for patients with end-stage liver disease. X-ray endovascular interventions show good results in the treatment of vascular complications after transplantation. The timing, indications and choice of treatment methods require clarification.Objective. To evaluate the safety and efficacy of emergency X-ray endovascular interventions for arterial complications in the early period after liver transplantation.Material and methods. In the period from October 2016 by July 2021, 88 liver transplants were performed. The graft was obtained from a posthumous donor in 75 cases, and from a living donor (right lobe of the liver) in 13 cases. Arterial complications were registered in 10 cases: thrombosis of the hepatic artery in 7 (8.0%), constriction in 3 (3.4%); 4 patients underwent retransplantation due to thrombosis. This analysis included 6 patients aged 27 to 51 years, including 4 men and 2 women. In the early postoperative period (0–14 days), according to laboratory parameters, ultrasound Doppler, and computed tomography with a contrast agent, an impairment of the arterial blood supply of the graft was revealed, for which the patients underwent emergency X-ray image-guided surgical endovascular interventions.Results. Restoration of adequate arterial blood supply to the liver graft was achieved in all six patients. At the time of this writing, the graft function and patency of the hepatic artery were preserved at follow-up periods of 6, 11, 12, 22 (in two patients), and 26 months with a median of 17 months. Four patients developed biliary complications that required surgical correction.Conclusion. X-ray image-guided endovascular interventions can be considered effective and relatively safe in the treatment of patients with arterial complications after liver transplantation. The period of graft arterial ischemia should be minimized as much as possible in order to prevent biliary complications.


2016 ◽  
Vol 157 (24) ◽  
pp. 964-970
Author(s):  
Fruzsina Tóth ◽  
Gergely Zádori ◽  
Roland Fedor ◽  
Dávid Ágoston Kovács ◽  
Zsolt Kanyári ◽  
...  

Introduction: Indication and timing of allograft nephrectomy is still uncertain in some cases. Aim: The aim of the authors was to summarize their experience with graftectomies. Method: Data from patients who underwent kidney transplantation between January 1, 2004 and December 31, 2015 were retrospectively analyzed. Frequency, indications, timing, complications as well as early and late allograft nephrectomies were reviewed. Results: From 480 renal transplants, 55 graftectomies were performed (11%). Frequent indications included chronic allograft nephropathy (47%), arterial blood supply complications (13%), ureter complications (9%). 22 cases (40%) of allograft nephrectomies were urgent while 33 cases (60%) were elective. 24% of graftectomies were performed within 30 days after transplantation and 76% thereafter. Conclusions: The main indications for early graftectomies were arterial complications (31%) and chronic allograft nephropathy (62%) in cases of late graftectomies. The majority of the graftectomies were elective. Leading indication was chronic allograft nephropathy. Early and late graftectomies have different characteristics. Orv. Hetil., 2016, 157(24), 964–970.


The present study was conducted on eight fresh forelimbs to investigate a detailed anatomical description of the arterial blood supply in adult dromedary camel’s foot. Anatomical and angiographic techniques were used in order to give detailed data about the origin and pattern of distribution of these arteries. Moreover, this data serve other researchers in comparison with different animals. The specimens injected with red colored gum milk latex for anatomical dissection and urograffin injection for angiographic purposes throughout the median artery. The main arterial blood supply of camel’s digit was derived from common palmar digital artery, palmar metacarpal artery, in addition to smaller branches detached from the dorsal metacarpal artery.


2015 ◽  
Vol 136 (1) ◽  
pp. 167-178 ◽  
Author(s):  
Charalambos A. Georgiou ◽  
Marc Benatar ◽  
Pierre Dumas ◽  
Bérengère Chignon-Sicard ◽  
Thierry Balaguer ◽  
...  

1984 ◽  
Vol 7 (1) ◽  
pp. 8-14 ◽  
Author(s):  
I. Eliachar ◽  
A. Marcovich ◽  
Y. Har Shai ◽  
E. Lindenbaum

ORL ◽  
2018 ◽  
Vol 80 (5-6) ◽  
pp. 238-247 ◽  
Author(s):  
Badr Eldin Mostafa ◽  
Talaat Ali Elsamny ◽  
Tamer Ali Youssef ◽  
Ahmed Bahaa Elserwi ◽  
Ahmed Abdelmoneim Teaima

Hand Surgery ◽  
1998 ◽  
Vol 03 (01) ◽  
pp. 63-69 ◽  
Author(s):  
H.-G. Simank ◽  
M. Schiltenwolf ◽  
W. Krempien

The etiology of the necrosis of the lunate bone is still unclear. In today's theories, the necrosis is explained by impairment of the arterial bone circulation or fracture following mechanical overloading. In this study, six specimen in different stages of the disease were investigated histologically. In all the specimens, focal necrosis was detected, but also signs of regeneration, i.e. immature bone formation. No signs of fracture were seen in all stages of the disease. These findings are not compatible with sudden interruption of arterial blood supply or fracture of the lunate bone as a primary lesion. Comparable histological patterns are known in the necrosis of the femoral head. The etiological model of necrosis of the femoral head is well investigated and postulates primary marrow hypertension, induced by impairment of the venous drainage. Our results are contradictory to the etiological theories of fracture or breakdown of the arterial blood supply as a primary lesion in Kienböck's disease, and support the assumption that the model of intraosseous hypertension is transferable to the necrosis of the lunate bone.


Endocrinology ◽  
1966 ◽  
Vol 78 (3) ◽  
pp. 648-651
Author(s):  
HANS SELYE ◽  
BEATRIZ TUCHWEBER ◽  
PAVEL ROHAN

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