c-Myb Is Required for Neural Progenitor Cell Proliferation and Maintenance of the Neural Stem Cell Niche in Adult Brain

Stem Cells ◽  
2008 ◽  
Vol 26 (1) ◽  
pp. 173-181 ◽  
Author(s):  
Jordane Malaterre ◽  
Theo Mantamadiotis ◽  
Sebastian Dworkin ◽  
Sally Lightowler ◽  
Qing Yang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Stem Cell ◽  
Neural Stem Cell ◽  
Stem Cell Niche ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Adult Brain ◽  
Progenitor Cell Proliferation ◽  
Cell Niche

scholarly journals Phosphoserine Phosphatase Is Expressed in the Neural Stem Cell Niche and Regulates Neural Stem and Progenitor Cell Proliferation

Stem Cells ◽  
2007 ◽  
Vol 25 (8) ◽  
pp. 1975-1984 ◽  
Author(s):  
Ichiro Nakano ◽  
Joseph D. Dougherty ◽  
Kevin Kim ◽  
Ivan Klement ◽  
Daniel H. Geschwind ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Stem Cell ◽  
Neural Stem Cell ◽  
Stem Cell Niche ◽  
Progenitor Cell ◽  
Phosphoserine Phosphatase ◽  
Neural Stem Cell Niche ◽  
Progenitor Cell Proliferation ◽  
Cell Niche

scholarly journals Inflammation Induced by Natural Neuronal Death and LPS Regulates Neural Progenitor Cell Proliferation in the Healthy Adult Brain

eNeuro ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. ENEURO.0023-20.2020 ◽  
Author(s):  
Tracy A. Larson ◽  
Yekaterina Tokareva ◽  
Marianne Meritt Cole ◽  
Eliot A. Brenowitz
Keyword(s):  
Cell Proliferation ◽  
Neuronal Death ◽  
Progenitor Cell ◽  
Healthy Adult ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Adult Brain ◽  
Progenitor Cell Proliferation

scholarly journals CXCR4/CXCL12 signaling impacts enamel progenitor cell proliferation and motility in the dental stem cell niche

2015 ◽  
Vol 362 (3) ◽  
pp. 633-642 ◽  
Author(s):  
Tamaki Yokohama-Tamaki ◽  
Keishi Otsu ◽  
Hidemitsu Harada ◽  
Shunichi Shibata ◽  
Nobuko Obara ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Stem Cell ◽  
Stem Cell Niche ◽  
Progenitor Cell ◽  
Progenitor Cell Proliferation ◽  
Cell Niche ◽  
Dental Stem Cell

scholarly journals Histone chaperone HIRA regulates neural progenitor cell proliferation and neurogenesis via β-catenin

2017 ◽  
Vol 216 (7) ◽  
pp. 1975-1992 ◽  
Author(s):  
Yanxin Li ◽  
Jianwei Jiao
Keyword(s):  
Cell Cycle ◽  
Cell Proliferation ◽  
Progenitor Cell ◽  
Neural Progenitor Cells ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Histone Chaperone ◽  
Epigenetic Mechanism ◽  
Progenitor Cell Proliferation ◽  
Early Neurogenesis

Histone cell cycle regulator (HIRA) is a histone chaperone and has been identified as an epigenetic regulator. Subsequent studies have provided evidence that HIRA plays key roles in embryonic development, but its function during early neurogenesis remains unknown. Here, we demonstrate that HIRA is enriched in neural progenitor cells, and HIRA knockdown reduces neural progenitor cell proliferation, increases terminal mitosis and cell cycle exit, and ultimately results in premature neuronal differentiation. Additionally, we demonstrate that HIRA enhances β-catenin expression by recruiting H3K4 trimethyltransferase Setd1A, which increases H3K4me3 levels and heightens the promoter activity of β-catenin. Significantly, overexpression of HIRA, HIRA N-terminal domain, or β-catenin can override neurogenesis abnormities caused by HIRA defects. Collectively, these data implicate that HIRA, cooperating with Setd1A, modulates β-catenin expression and then regulates neurogenesis. This finding represents a novel epigenetic mechanism underlying the histone code and has profound and lasting implications for diseases and neurobiology.

Neural-specific inactivation of ShcA functions results in anatomical disorganization of subventricular zone neural stem cell niche in the adult brain

Neuroscience ◽  
2010 ◽  
Vol 168 (1) ◽  
pp. 314-322 ◽  
Author(s):  
G. Ponti ◽  
E. Reitano ◽  
P. Aimar ◽  
E. Cattaneo ◽  
L. Conti ◽  
...  
Keyword(s):  
Stem Cell ◽  
Neural Stem Cell ◽  
Subventricular Zone ◽  
Stem Cell Niche ◽  
Adult Brain ◽  
Neural Stem Cell Niche ◽  
Cell Niche

scholarly journals Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation

2006 ◽  
Vol 296 (2) ◽  
pp. 396-408 ◽  
Author(s):  
Zhongxian Jiao ◽  
Zheng Gang Zhang ◽  
Thomas J. Hornyak ◽  
Ann Hozeska ◽  
Rui Lan Zhang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Dopachrome Tautomerase ◽  
Progenitor Cell Proliferation

FGF‐4 regulates neural progenitor cell proliferation and neuronal differentiation

2006 ◽  
Vol 20 (9) ◽  
pp. 1484-1485 ◽  
Author(s):  
Nobuyoshi Kosaka ◽  
Maho Kodama ◽  
Hideo Sasaki ◽  
Yusuke Yamamoto ◽  
Fumitaka Takeshita ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Neuronal Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Progenitor Cell Proliferation
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