scholarly journals Growth factor-driven mechanisms associated with resistance to estrogen deprivation in breast cancer: new opportunities for therapy

2004 ◽  
Vol 11 (4) ◽  
pp. 623-641 ◽  
Author(s):  
R I Nicholson ◽  
C Staka ◽  
F Boyns ◽  
I R Hutcheson ◽  
J M W Gee
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Breast Cancer Cells ◽  
Endocrine Resistance ◽  
Signaling Networks ◽  
Growth Factor Signaling ◽  
Independent Manner ◽  
Estrogen Withdrawal ◽  
Current Article ◽  
The Many

There is an increasing body of evidence demonstrating that elevated growth signaling in breast cancer cells can promote forms of endocrine resistance in either an estrogen receptor-dependent or -independent manner. The current article reviews what is known about such growth factor signaling networks and resistance to estrogen withdrawal and considers the many novel therapeutic opportunities that stem from this knowledge.

scholarly journals ZIP7-Mediated Intracellular Zinc Transport Contributes to Aberrant Growth Factor Signaling in Antihormone-Resistant Breast Cancer Cells

Endocrinology ◽  
2008 ◽  
Vol 149 (10) ◽  
pp. 4912-4920 ◽  
Author(s):  
Kathryn M. Taylor ◽  
Petra Vichova ◽  
Nicola Jordan ◽  
Stephen Hiscox ◽  
Rhiannon Hendley ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Growth Factor Signaling ◽  
Zinc Transport ◽  
Intracellular Zinc

Abstract 531: Obesity-associated growth factor signaling upregulates aromatase expression in breast cancer cells

2011 ◽  
Author(s):  
Laura W. Bowers ◽  
Rebecca De Angel ◽  
David Cavazos ◽  
Stephen Hursting ◽  
Andrew Brenner ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Growth Factor Signaling ◽  
Aromatase Expression
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