scholarly journals Liver metastasis from an ovarian Yolk-Sac-Tumor: A case report and review of the literature

2021 ◽  
pp. 071-074
Author(s):  
Ezzahra Aboutarik Fatima ◽  
Maroua Michouar ◽  
Adil Ait Errami ◽  
Sofia Oubaha ◽  
Zouhour Samlani ◽  
...  
Keyword(s):  
Ovarian Tumor ◽  
Abdominal Mass ◽  
Stage Iv ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
Abdominal Magnetic Resonance Imaging ◽  
The Right ◽  
Sinus Tumor ◽  
Immunohistological Study

The endodermal sinus tumor or Yolk sac tumor is a rare ovarian tumor that classically occurs in adolescents and young women, it is a histological type rarely found in clinical practice. We report the case of a 24-year-old woman presenting with an ovarian tumor of the endodermal sinus with hepatic metastasis revealed by a painful abdominal mass in the right hypochondrium associated with a deterioration of the general condition. The blood Alpha-Fetoprotein (AFP) level was 71,300 ng / ml. Abdominal magnetic resonance imaging revealed multiple liver nodules and masses, associated with a magma of secondary lymphadenopathy. The immunohistological study of the hepatic puncture biopsy allowed the diagnosis of a hepatic localization of an ovarian endodermal sinus tumor (Yolk-Sac-Tumor). The tumor was classified stage IV-B of the FIGO 2014 classification, which does not allow a curative approach. Chemotherapy treatment (BEP protocol) was started.

scholarly journals Ultrasound case of the day. Endodermal sinus tumor (yolk sac tumor) of the right ovary.

Radiographics ◽  
1986 ◽  
Vol 6 (4) ◽  
pp. 734-737
Author(s):  
M A Sandler ◽  
R Walter ◽  
G H Beute ◽  
A H Haggar ◽  
B L Madrazo ◽  
...  
Keyword(s):  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
The Right ◽  
Sinus Tumor

Endodermal Sinus Tumor (Yolk Sac Tumor) of the Ear

1987 ◽  
Vol 113 (2) ◽  
pp. 200-203 ◽  
Author(s):  
R. J. Stanley ◽  
B. W. Scheithauer ◽  
E. I. Thompson ◽  
D. B. Kispert ◽  
L. H. Weiland ◽  
...  
Keyword(s):  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
Sinus Tumor

scholarly journals Extragonadal endodermal sinus tumor (yolk sac tumor) of the pelvis

Cancer ◽  
1971 ◽  
Vol 27 (2) ◽  
pp. 391-396 ◽  
Author(s):  
Juergen Thiele ◽  
Salvador Castro ◽  
Kirsten D. Lee
Keyword(s):  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
Sinus Tumor

scholarly journals Pathogenesis of intracranial germ cell tumors reconsidered

1998 ◽  
Vol 5 (1) ◽  
pp. E3
Author(s):  
Keiji Sano
Keyword(s):  
Survival Rate ◽  
Germ Cell ◽  
Mature Teratoma ◽  
Germ Cell Tumors ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Single Type ◽  
Endodermal Sinus Tumor ◽  
Intracranial Germ Cell Tumors ◽  
Sinus Tumor

The author studied 153 cases of intracranial germ cell tumors (GCTs) through 1994, 62.7% of which showed monotypic histological patterns and 37.3% of which were shown to be mixed tumors. All of these cases, except for six patients who died soon after admission and underwent autopsy, underwent surgery followed by radio- and/or chemotherapy. All patients with choriocarcinoma died within 2 years. Patients with yolk sac tumor (endodermal sinus tumor) and embryonal carcinoma also had poor outcomes. Patients with mature teratoma had 5- and 10-year survival rates of 92.9% each. Patients with immature teratoma and malignant teratoma had a 5- and 10-year survival rate of 70.7% each. Patients with germinoma had a 5-year survival rate of 95.4% and a 10-year survival rate of 92.7%. These results may bring into question the validity of the germ cell theory, because germinoma, which should be the most undifferentiated according to the theory, was the most benign and choriocarcinoma and yolk sac tumor (endodermal sinus tumor), which should be the most differentiated, were the most malignant according to results obtained during follow-up study. Therefore, GCTs other than germinoma may not originate from one single type of cell (primordial germ cells). The embryonic cells of various stages of embryogenesis may perhaps be misplaced in the bilaminar embryonic disc at the time of the primitive streak formation, becoming involved in the stream of lateral mesoderm and carried to the future cranial area to become incorrectly enfolded into the brain at the time of the neural tube formation. The authors propound the following law: tumors composed of cells resembling the cells that appear in the earlier stages of embryogenesis (ontogenesis) are more malignant than those composed of cells resembling the cells that appear in the later stages of embryogenesis.

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