scholarly journals Left ventricular wall myocardium structural and functional indices change in patients with arterial hypertension and subclinical hypothyroidism treated with hypotensives

2013 ◽  
Vol 94 (3) ◽  
pp. 289-293
Author(s):  
N V Soldatenko ◽  
L N Yeliseyeva ◽  
O I Zhdamarova
Keyword(s):  
Mitral Valve ◽  
Arterial Hypertension ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Ventricular Wall ◽  
Diastolic Left Ventricular Filling ◽  
Group 2 ◽  
Ventricular Filling ◽  
Functional Indices ◽  
Group 1

Aim. To assess the left ventricular wall myocardium structural and functional indices change over time in patients receiving hypotensive treatment for arterial hypertension associated with subclinical hypothyroidism. Methods. Sixty eight patients with arterial hypertension and subclinical hyperthyroidism were distributed to two groups. Patients of the group 1 (37 patients) received amlodipine (5-10 mg/day) and indapamide (1.5 mg/day), patients of the group 2 (31 patients) received lisinopril (5-10 mg/day) and indapamide (1.5 mg/day). Carotid artery ultrasonography and echocardiography were performed using «Philips» HD-11 XE (USA) scanner on the baseline and after 18 months of treatment. Results. Initial parameters of the left ventricular wall myocardium in all patients were comparable. Significant increase in early diastolic left ventricular filling velocity by 5.2%, decrease of late diastolic filling velocity by 11.4%, increase of peak velocities ratio on the mitral valve by 19.7% were revealed in patients of group 1 after 18 months of treatment compared to baseline. Increase in early diastolic left ventricular filling velocity by 7.0%, increase of peak velocities ratio on the mitral valve by 13.9% were registered in patients of group 2. No signs of concentric left ventricle remodeling were revealed. The share of patients with eccentric hypertrophy was not altered (18.9 and 12.9%, respectively). Conclusion. Treatment with amlodipine + indapamine and lisinopril + indapamine during 18 months improves left ventricle diastolic function.

Abstract 1756: Determination of the Mechanism of Elevated Left Ventricular Filling Pressures with Exercise: A Simultaneous Echocardiographic-Catheterization Study

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Wissam A Jaber ◽  
Barry A Borlaug ◽  
Margaret M Redfield ◽  
Pui W Lee ◽  
Steve R Ommen ◽  
...  
Keyword(s):  
Exercise Group ◽  
Left Ventricular ◽  
Filling Pressure ◽  
Ventricular Relaxation ◽  
Rate Table ◽  
Group 2 ◽  
Exercise Induced ◽  
Ventricular Filling ◽  
Group 1

Background: Exercise normally enhances LV relaxation with minimal change in filling pressure (P). We hypothesize that exercise in hypertensive (HTN) patients increases LV diastolic P through a direct effect on relaxation and ventricular-vascular coupling. Methods: Patients (n=21) with HTN, normal EF, and no coronary disease underwent simultaneous micromanometer LV P and echo-Doppler measurements at rest and with low level supine exercise (12 bicycle; 9 arm weight). Continuous volume (V) was obtained from mitral Doppler inflow and end-diastolic (ED) and end-systolic (ES) V from 2-D echo. Relaxation-corrected LV diastolic P was used for PV relationship P = α.e β*V ; to account for covariance in α and β, LV capacitance (EDV 20 = Ln[20mmHg/α]/β) was reported. Single beat method was used for LV ES elastance (Ees). Group 1 did not increase mean LV diastolic P (mDP) with exercise, Group 2 increased mDP >6mmHg. Results: LV diastolic P and arterial and LV ES elastance increased with exercise; EDV was stable; EDV 20 decreased. Compared to Group 1, Group 2 had a greater exercise-induced increase in afterload, associated with increase in LV minimal P and impaired augmentation of relaxation rate (Table & Figure ). Conclusions: In patients with HTN, impairment of ventricular relaxation plays a major role in causing LV filling P increase with exercise, which is related to ventricular-vascular coupling.

Intraoperative Posterior Left Ventricular Wall Rupture Associated with Mitral Valve Replacement

1978 ◽  
Vol 25 (6) ◽  
pp. 551-554 ◽  
Author(s):  
Allan Wolpowitz ◽  
Marius S. Barnard ◽  
Hector E. Sánchez ◽  
Christiaan N. Barnard
Keyword(s):  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Ventricular Wall

scholarly journals PECULIAR FEATURES OF STRUCTURAL AND FUNCTIONAL INDICES OF CARDIOVASCULAR SYSTEM IN YOUNG MEN WITH ARTERIAL HYPERTENSION ASSOCIATED WITH METABOLIC SYNDROME

2017 ◽  
Vol 34 (6) ◽  
pp. 17-21
Author(s):  
R T Rizvanova ◽  
N I Maksimov
Keyword(s):  
Arterial Hypertension ◽  
Cardiovascular System ◽  
Antihypertensive Therapy ◽  
Dynamic Assessment ◽  
Young Men ◽  
Systolic Arterial Pressure ◽  
Cardiovascular Complications ◽  
Group 2 ◽  
Functional Indices ◽  
Group 1

Aim. To carry out dynamic assessment of the structural and functional indices of cardiovascular system in young men with arterial hypertension (AH) associated with excess body mass (Ebm) against the background of therapy. Materials and methods. Examination of 86 young men aged 18-27 years, including the group of comparison with practically healthy persons ( n = 24) and the group of observation ( n = 62) was performed. The group of observation joined patients with AH without EBM and AH+EBM. The study was conducted initially and 6 months later. Patients with AH+EBM ( n = 25) were divided into 2 subgroups: group 1 (12 persons) without therapy and group 2 (13 persons) against the background of antihypertensive therapy. Results. Six months later, in group 1 there was observed a growth of “office” systolic arterial pressure (SAP) by 3,8 % (145,0 ± 2,88 and 150,54 ± 2,99 Hg mm), p = 0,001, but in the group with antihypertensive therapy, SAP decreased by 12,7 % (145,75 ± 2,80 and 129,33 ± 1,5 Hg mm), p = 0,01 and DAP - by 12,1 % (86,5 ± 1,95 and 77,16 ± 2,41 Hg mm), p = 0,02. Pulse wave propagation velocity (PWPV) along the vessels of muscular and elastic types among patients without therapy was found to grow in dynamics by 12,2 and 16,2 %, respectively. Against the background of therapy, there was a tendency to a reliable reduction in PWPV indices. Conclusions. Antihypertensive therapy in patients with AH+EBM, while decreasing AP, leads to reduction of LVMM, LVMMI, PWPV and IMCV. The early diagnosed lesion of target organs among young men with AH+EBM and timely antihypertensive therapy can improve structural and functional characteristics of cardiovascular complications.

scholarly journals AN INFLAMMATORY PSEUDOTUMOR INFILTRATING THE MITRAL VALVE AND THE LEFT VENTRICULAR WALL

2020 ◽  
Vol 75 (11) ◽  
pp. 2727
Author(s):  
Hibiki Mima ◽  
Yodo Tamaki ◽  
Hamguchi Yukihiro ◽  
Maki Hamsaki ◽  
Kojima Hidenori ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Inflammatory Pseudotumor ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Ventricular Wall

Echocardiographic study of left ventricular wall motion in mitral valve prolapse

1984 ◽  
Vol 108 (1) ◽  
pp. 105-110 ◽  
Author(s):  
Yoshinori L. Doi ◽  
David H. Spodick ◽  
Naohisa Hamashige ◽  
Yoshihiro Yonezawa ◽  
Tetsuro Sugiura ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Wall Motion ◽  
Left Ventricular ◽  
Left Ventricular Wall ◽  
Ventricular Wall ◽  
Left Ventricular Wall Motion ◽  
Echocardiographic Study ◽  
Ventricular Wall Motion
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