scholarly journals Transdermal estradiol as a novel treatment for Peyronie's disease: A case report

2020 ◽  
Vol 10 (1) ◽  
pp. 37-39
Author(s):  
Jessie Thuswaldner

Introduction: This is a single‐patient case report of a (now) 75-year old married male with long-standing Peyronie’s disease (PD).  The patient’s main symptoms were painful erections as well as secondary anxiety and depression.  Resolution of these symptoms was achieved with transdermal estradiol treatment. Objectives: To describe a patient with PD, whose persistently painful erections and psychologic distress were eliminated by a novel treatment involving transdermal estradiol. This report also aims to present a novel treatment for patients with paraphilias. Methods: An interview with the patient, chart review, and a literature search were conducted. Informed consent was obtained from the patient and this report was approved by the Research Ethics Committee at the Royal Hospital in Ottawa. Results: Treatment with transdermal estradiol decreased the patient’s sex drive and virtually eliminated his erections with no undesirable side effects. The patient and his wife still enjoy sexual relations without the need for penile erection. Conclusions: This case report presents a novel treatment for PD. It also introduces a novel method to treat men who wish to decrease their sex drive (e.g. men with paraphilic disorders). Replication of this treatment intervention in men with PD and new studies of its use in men with paraphilic disorders are warranted.

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Jintakorn Kuvatanasuchati ◽  
Karoon Leowsrisook

Abstract Background Chronic facial pain is a serious condition affecting millions of people worldwide. The reasons for chronic facial pain vary, and currently, the methods of treating chronic facial pain are expensive, invasive, and, based on current findings, ineffective. The purpose of this study is to develop and test an effective, cost-friendly method to treat patients with chronic facial pain. This study will examine the effectiveness of a novel treatment of a patient suffering from trigeminal neuralgia. Case presentation A 70-year-old Thai female visited the advanced general dentistry clinic at the Faculty of Dentistry, Mahidol University, Bangkok, Thailand. She was suffering from facial pain on her left side and was diagnosed by a physician as having trigeminal neuralgia. She experienced a sharp shooting pain that was triggered by facial movements such as chewing, speaking, or brushing teeth, and touching certain areas of her face. Bouts of pain lasted from a few seconds to several minutes, and episodes of several attacks lasted days, weeks, months, or longer prior to her visit to the advanced general dentistry clinic at Mahidol University. Physician designed an occlusal equilibration appliance for treating the patient by inserting the appliance in the mouth for dental occlusal equilibration (deprogram). The patient used this appliance by placing it in the mouth continuously (day and night) and removed it only when eating. After using the appliance for 2 weeks, the patient appeared to feel and look better prior to taking medication and was able to eat normally. The patient was pain free after treatment for a duration of 9 months. However, after 9 months, the pain reoccurred and manifested itself. Conclusion This novel treatment of recurrent facial pain showed an improvement of the patient’s chronic facial pain and serves as evidence to being a novel method for treating those suffering from trigeminal neuralgia.


2016 ◽  
Vol 17 (1) ◽  
pp. 20 ◽  
Author(s):  
OlajideOlusegun Abiola ◽  
IbukunOlalekan Oyinloye ◽  
SegunOladele Adeniyi

2018 ◽  
Vol 36 (3) ◽  
pp. 117-120 ◽  
Author(s):  
Iacob Marcovici

Many men with Peyronie’s disease are embarrassed and choose to suffer in silence rather than get help. Peyronie’s disease can be a physically and psychologically devastating. This case report presents a successful correction of penile curvature using platelet rich plasma (PRP) treatment in an office setting.


Andrologia ◽  
2021 ◽  
Author(s):  
Quinn Rainer ◽  
Manuel Molina ◽  
Emad Ibrahim ◽  
Russell Saltzman ◽  
Thomas Masterson ◽  
...  

2017 ◽  
Vol 4 (20) ◽  
pp. 1169-1171
Author(s):  
Vikram Are ◽  
Srihari Kummari ◽  
Venkat Ram Reddy Kuchukula K ◽  
Satyanarayana Moorty R.(Brig) ◽  
Rama Krishna Reddy G

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