scholarly journals Higher gene expression stability during aging in long-lived giant mole-rats than in short-lived rats

Aging ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 3938-3956 ◽  
Author(s):  
Arne Sahm ◽  
Martin Bens ◽  
Yoshiyuki Henning ◽  
Christiane Vole ◽  
Marco Groth ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Stability ◽  
Gene Expression Stability

Multiplex qPCR assay for assessment of reference gene expression stability in rat tissues/samples

2020 ◽  
Vol 53 ◽  
pp. 101611 ◽  
Author(s):  
Alexander P. Schwarz ◽  
Daria A. Malygina ◽  
Anna A. Kovalenko ◽  
Alexander N. Trofimov ◽  
Aleksey V. Zaitsev
Keyword(s):  
Gene Expression ◽  
Reference Gene ◽  
Qpcr Assay ◽  
Rat Tissues ◽  
Expression Stability ◽  
Gene Expression Stability ◽  
Multiplex Qpcr ◽  
Reference Gene Expression

Impact of Thawing on Reference Gene Expression Stability in Renal Cell Carcinoma Samples

2012 ◽  
Vol 21 (3) ◽  
pp. 157-163 ◽  
Author(s):  
Yi Ma ◽  
HuiLi Dai ◽  
XianMing Kong ◽  
LiMin Wang
Keyword(s):  
Gene Expression ◽  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Reference Gene ◽  
Renal Cell ◽  
Expression Stability ◽  
Gene Expression Stability ◽  
Reference Gene Expression

Gene expression stability of candidate reference genes under different culture conditions for quantitative PCR in the raphidophyte Chattonella marina

Phycologia ◽  
2020 ◽  
Vol 59 (6) ◽  
pp. 556-565
Author(s):  
Koki Mukai ◽  
Yohei Shimasaki ◽  
Xuchun Qiu ◽  
Yoko Kato-Unoki ◽  
Kun Chen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Quantitative Pcr ◽  
Reference Genes ◽  
Culture Conditions ◽  
Expression Stability ◽  
Chattonella Marina ◽  
Gene Expression Stability

scholarly journals Stable maintenance of a hidden switch as a way to increase the gene expression stability

2019 ◽  
Author(s):  
Hiroyuki Kuwahara ◽  
Xin Gao
Keyword(s):  
Gene Expression ◽  
Phenotypic Switching ◽  
Stabilizing Selection ◽  
Expression Stability ◽  
Gene Expression Stability ◽  
Gene Expression Noise ◽  
Founding Population ◽  
Alternative Phenotypes ◽  
Bistable Systems ◽  
Stable Maintenance

AbstractIn response to severe stress, wild-type organisms can release alternative phenotypes that are hidden under normal conditions and are associated with underlying genetic variations. A number of such stress-induced phenotypic switchings have been reported to be based on reactivation of hidden thresholds; under the normal condition, a high barrier separating alternative phenotypes ensures the expression of single discrete phenotype, but a severe perturbation can lower the barrier to a level at which to expose cryptic alternatives. While the importance of such threshold-based switches as the mechanism to generate adaptive novelties under variable environments has been appreciated, it still remains elusive how naturally selected organisms can maintain the phenotypic switching capability when such switching has been disused for a long period of time. Here, through the use of computer simulation, we analyzed adaptive evolution of gene circuits under stabilizing selection. We found that different strategies evolved to acquire reduced levels of gene expression noise around the optimum expression level. To incrementally improve the gene expression stability from a founding population with bistable individuals, the evolution consistently took the direction to raise the height of the potential barrier of bistable systems. Our results demonstrate that hidden phenotypic switches can be stably maintained during environmental stasis, facilitating the release of potentially adaptive phenotypic alternatives in the event of substantial perturbations.

scholarly journals Impact of RNA quality on reference gene expression stability

BioTechniques ◽  
2005 ◽  
Vol 39 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Claudina Angela Pérez-Novo ◽  
Cindy Claeys ◽  
Frank Speleman ◽  
Paul Van Cauwenberge ◽  
Claus Bachert ◽  
...  
Keyword(s):  
Gene Expression ◽  
Reference Gene ◽  
Expression Stability ◽  
Gene Expression Stability ◽  
Rna Quality ◽  
Reference Gene Expression

scholarly journals Evaluation of housekeeping gene expression stability in carnation (Dianthus caryophyllus)

2021 ◽  
pp. 1-14
Author(s):  
Wenjing Yu ◽  
Yuan Tao ◽  
Liping Luo ◽  
Jonathan Hrovat ◽  
Ahui Xue ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dianthus Caryophyllus ◽  
Housekeeping Gene ◽  
Expression Stability ◽  
Gene Expression Stability

Abstract 3275: Molecular characterization of human breast cancer xenografts reveals a strong genomic and gene expression stability

2010 ◽  
Author(s):  
Fabien Reyal ◽  
Charlotte Guyader ◽  
Charles Decraene ◽  
Carlo Lucchesi ◽  
Nathalie Auger ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Molecular Characterization ◽  
Human Breast Cancer ◽  
Expression Stability ◽  
Human Breast ◽  
Gene Expression Stability ◽  
Breast Cancer Xenografts
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