Diffuse Large B-Cell Lymphoma Complicated by Small Bowel Obstruction after Radiotherapy: a Case Study

There have been several reports of complications of small bowel lymphoma, such as bleeding, obstruction, and perforation, often require emergency surgery. It is hardly showed complications of bleeding and wound dehiscence for diffuse large B cell lymphoma with distal ileum involvement, which needed urgent surgery and medical management. A 65-year-old man with diffuse large B-cell lymphoma with distal ileum involvement experienced both intestinal bleeding and perforation during the course of treatment. As the patient was diagnosed with stage III disease, resection before chemotherapy was not considered due to the resulting delay in chemotherapy, which necessitated sufficient tissue healing. Chemotherapy is important when treating small bowel lymphoma, complications such as bleeding and perforation should always be considered for the treatment of small bowel lymphoma, and surgery is necessary in this situation. After surgery of the small bowel, subsequent chemotherapy could cause wound dehiscence and perforation; therefore, adequate recovery time should be given before chemotherapy.

Download Full-text

Primary small-bowel diffuse large B-cell lymphoma presenting as hematemesis

Endoscopy ◽

10.1055/s-0034-1392874 ◽

2015 ◽

Vol 47 (S 01) ◽

pp. E526-E528 ◽

Cited By ~ 1

Author(s):

Paul Kröner ◽

Pavan Mankal ◽

Abdelaziz Elhaddad ◽

Wenjing Shi ◽

Jean Abed ◽

...

Keyword(s):

Small Bowel ◽

B Cell ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Large B Cell Lymphoma ◽

Large B Cell ◽

Primary Small Bowel

Download Full-text

Spontaneous Regression of Hepatic Diffuse Large B-cell Lymphoma in HIV and HCV Positive Patient: A Novel Case Study

International Journal of Cancer and Clinical Research ◽

10.23937/2378-3419/1410127 ◽

2019 ◽

Vol 6 (5) ◽

Author(s):

Alhatem Albert ◽

Badeti Saiaditya ◽

Liu Chen ◽

Liu Dongfang ◽

Cai Donghong

Keyword(s):

B Cell ◽

Spontaneous Regression ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Positive Patient ◽

Large B Cell Lymphoma ◽

Large B Cell

Download Full-text

Experience of Serious Intestinal Hemorrhage and Perforation in Small Bowel Lymphoma: A Case Report

10.21203/rs.3.rs-877505/v1 ◽

2021 ◽

Author(s):

Seo Ree Kim ◽

Sang Hoon Chun ◽

Jong Youl Jin ◽

Tae-Geun Gweon ◽

Hayemin Lee ◽

...

Keyword(s):

Small Bowel ◽

B Cell ◽

Cell Lymphoma ◽

Wound Dehiscence ◽

B Cell Lymphoma ◽

Distal Ileum ◽

Stage Iii ◽

Intestinal Bleeding ◽

Large B Cell Lymphoma ◽

Large B Cell

Abstract Background: There have been several reports of complications of small bowel lymphoma, such as bleeding, obstruction, and perforation, which require emergency surgery. It is hardly showed complication of bleeding and wound dehiscence for diffuse large B cell lymphoma with distal ileum involvement, which needed urgent surgery and medical management. Chemotherapy is also important when treating small bowel lymphoma, but complications such as bleeding and perforation should always be kept in mind.Case presentation: A 65 year-old man with stage III diffuse large B-cell lymphoma of the activated-B cell (ABC) type with distal ileum involvement experienced both intestinal bleeding and perforation during the course of treatment. As the patient was diagnosed with stage III disease, resection before chemotherapy was not considered due to the resulting delay in chemotherapy, which necessitated sufficient tissue healing. Conclusion: As shown in this case, complications such as bleeding and perforation should always be considered for the treatment of small bowel lymphoma, and surgery is necessary in this situation. After surgery of the small bowel, subsequent chemotherapy could cause the wound dehiscence and perforation; therefore, adequate recovery time should be given before chemotherapy.

Download Full-text

Linfoma Difuso de Grandes Células B de Intestino Delgado: Relato de Caso/Diffuse Large B-Cell Lymphoma of Small Bowel: Case Report

REVISTA CIÊNCIAS EM SAÚDE ◽

10.21876/rcsfmit.v2i2.95 ◽

1970 ◽

Vol 2 (2) ◽

pp. 67-72

Author(s):

Gustavo Nunes Medina Coeli ◽

Afonso Carlos da Silva ◽

Rodrigo Ribeiro Tiengo ◽

Guilherme Carlos da Silva ◽

Leandro Urquiza Marques Alves da Silva ◽

...

Keyword(s):

Case Report ◽

Small Bowel ◽

B Cell ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Large B Cell Lymphoma ◽

Large B Cell ◽

Intestino Delgado

Introdução: Os tumores do intestino delgado são raros, de diagnóstico difícil e quando malignos, têm prognóstico ruim. Os linfomas primários representam menos de 2% de todos os tumores gastrointestinais malignos, sendo na sua maioria do subtipo de células B. Casuística: Foi relatado um caso raro de linfoma de intestino delgado em uma paciente do sexo feminino de 77 anos, que procurou atendimento médico com sintomas inespecíficos e um quadro anêmico. Os exames radiológicos foram fundamentais para esclarecimento, diagnóstico e propedêutica. Os marcadores tumorais foram negativos e as provas de atividade inflamatória, positivas. Na internação, a paciente teve piora súbita do quadro clínico, necessitando de cirurgia. No intra-operatório, foi identificado lesão perfurativa em jejuno proximal de aspecto ulcerado com aderências na bexiga e fundo do útero. A paciente não evoluiu bem, falecendo após três dias. A patologia confirmou Linfoma Não Hodgkin Difuso de Grandes Células B, com elevado índice de proliferação celular. Discussão: O diagnóstico radiológico pré-operatório do tumor do intestino delgado só é obtido em um pequeno percentual de pacientes sintomáticos. Estudos por imagem demonstram aspectos morfológicos do tipo infiltrativo, polipóide ou aneurismático. Geralmente, ocorre acometimento circunferencial da alça, com espessamento irregular das pregas, de extensão variável. Conclusão: O objetivo deste estudo foi documentar um raro tumor do intestino delgado do tipo Linfoma Não-Hodgkin Difuso de Grandes Células B, multicêntrico, de difícil diagnóstico e com rápida evolução dos sintomas, que culminaram com quadro de obstrução intestinal aguda, necessitando de cirurgia de emergência. Palavras chave: Tumor de intestino delgado, linfoma de intestino, obstrução.

Download Full-text