scholarly journals Pregnancy outcomes, early separation and psychiatric relapse experienced by South African women with peripartum psychosis: A descriptive exploration

2019 ◽  
Author(s):  
Juané Voges ◽  
Astrid Berg ◽  
Dana JH Niehaus

Abstract Background: The peripartum period is associated with increased incidence of severe mental illness (SMI), with a greater occurrence of psychotic symptoms and psychiatric admissions. There has been little research on South African mothers with peripartum psychosis to examine what factors contribute to their experiences of pregnancy and the postpartum period. This study aimed to explore the relevant socio-demographic factors and pregnancy outcomes in order to determine focus areas for intervention. Methods: Using a prospective, descriptive design, we conducted a detailed interview and supplementary information was collected by review of clinical records. The study examined the accounts of thirty-two mothers who experienced peripartum psychosis between 6 and 18 months postpartum. Areas of focus included participants’ current circumstances, their pregnancy, birth and postpartum experiences. Results: The majority of mothers were diagnosed with bipolar disorder and all but one have had one psychiatric admission. Pregnancies were predominantly unplanned (87.5%) and half of participants reported substance use during pregnancy. Medical or psychiatric problems during pregnancy occurred in 68.8% of pregnancy and 71.9% of mothers reported complications with delivery. Common psychosocial stressors included trauma, lack of partner support and financial hardship. Early separation occurred in 56.3% of dyads, mostly due to psychiatric admission. Conclusion: Our study describes psychiatric, medical and psycho-social risk factors affecting mothers who experienced peripartum psychosis. We discuss the implications of the findings for a developing country where there exists a lack of integrated maternal and infant mental health services. The results highlight the need for close obstetric and psychiatric follow-up for women with serious mental illness, with particular attention to screening for substance use and psychosocial stressors.

2014 ◽  
Vol 26 (2) ◽  
pp. 297-301 ◽  
Author(s):  
Mariam Rahmani ◽  
Sean Paul ◽  
Mathew L. Nguyen

Abstract This article presents two cases of adolescent males who were admitted to our inpatient psychiatric unit with a psychotic, disorganized presentation. Both males had a genetic vulnerability to mental illness and reported significant substance use. Their symptoms were refractory to treatment and required the use of clozapine. Both patients experienced significant side effects, which limited the maximum daily dose of clozapine. However, they responded to a dose that was much lower than that typically used in adults. There is significant evidence in the literature about cannabis use triggering psychotic breaks in vulnerable individuals. We speculate that substance use (including synthetic cannabinoids) triggers treatment-resistant psychosis that requires the use of clozapine. Further, lower doses of clozapine may be sufficient to treat the substance-induced psychotic symptoms than those typically used in adult schizophrenia.


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