Evaluation of Liposome-Encapsulated Hemoglobin/LR16 Formulation as a Potential Blood Substitute

1991 ◽  
Author(s):  
Thomas G. Burke
Keyword(s):  
Blood Substitute

Sinusoidal Cells in Bone Marrow Take Up BSA-Au Conjugates in the Presence of an Artificial Blood Substitute

1985 ◽  
Vol 43 ◽  
pp. 700-701
Author(s):  
J.S. Geoffroy ◽  
R.P. Becker
Keyword(s):  
Bone Marrow ◽  
Los Angeles ◽  
Iliac Artery ◽  
Blood Substitute ◽  
Sprague Dawley ◽  
Coated Pits ◽  
Sinusoidal Cells ◽  
Artificial Blood ◽  
Left Common Iliac Artery

The pattern of BSA-Au uptake in vivo by endothelial cells of the venous sinuses (sinusoidal cells) of rat bone marrow has been described previously. BSA-Au conjugates are taken up exclusively in coated pits and vesicles, enter and pass through an “endosomal” compartment comprised of smooth-membraned tubules and vacuoles and cup-like bodies, and subsequently reside in multivesicular and dense bodies. The process is very rapid, with BSA-Au reaching secondary lysosmes one minute after presentation. (Figure 1)In further investigations of this process an isolated limb perfusion method using an artificial blood substitute, Oxypherol-ET (O-ET; Alpha Therapeutics, Los Angeles, CA) was developed. Under nembutal anesthesia, male Sprague-Dawley rats were laparotomized. The left common iliac artery and vein were ligated and the right iliac artery was cannulated via the aorta with a small vein catheter. Pump tubing, preprimed with oxygenated 0-ET at 37°C, was connected to the cannula.

Study of efficiency of action of a new domestic protein-salt blood substitute at the peritonite

2018 ◽  
Vol 2 (1) ◽  
pp. 20-25
Author(s):  
Hamid KARIMOV ◽  
◽  
Shavkat ALIYEV ◽  
Larisa SHEVCHENKO ◽  
Timur ALIMOV
Keyword(s):  
Blood Substitute

Fluorocarbon emulsions as a synthetic blood substitute: Effects on microvascular hemodynamics in the rabbit omentum

1980 ◽  
Vol 29 (6) ◽  
pp. 516-526 ◽  
Author(s):  
Bernhard Endrich ◽  
Melvin M. Newman ◽  
A.Gerson Greenburg ◽  
Marcos Intaglietta
Keyword(s):  
Blood Substitute

Human erythrocytes cross-linked with glutaraldehyde general properties and significance as a blood substitute

1988 ◽  
Vol 156 (2) ◽  
pp. 970-977 ◽  
Author(s):  
A. Bellelli ◽  
P.L. Benedetti ◽  
M. Coletta ◽  
R. Ippoliti ◽  
M. Brunori
Keyword(s):  
Blood Substitute ◽  
Human Erythrocytes ◽  
General Properties

Cytotoxicity of a perfluorocarbon blood substitute to macrophages in vitro

Science ◽  
1983 ◽  
Vol 220 (4600) ◽  
pp. 965-967 ◽  
Author(s):  
R Bucala ◽  
M Kawakami ◽  
A Cerami
Keyword(s):  
Blood Substitute

A Blood Substitute from Hydroxyethyl Starch and Hemoglobin

1984 ◽  
pp. 151-153
Author(s):  
L. C. Cerny ◽  
E. L. Cerny ◽  
J. Robach ◽  
M. Reath ◽  
L. Pontero
Keyword(s):  
Hydroxyethyl Starch ◽  
Blood Substitute
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