Fine needle Aspiration Cytology: Diagnostic Efficacy in Malignant Breast Lesions

Abstract Background Fine needle aspiration cytology is a simple, relatively accurate, non-invasive, and cost-effective method of diagnosing most breast pathologies. To date, there is no sufficient data depicting the distribution of breast lesions detected by fine needle aspiration cytology in our healthcare setting. The aim of this study was to elucidate the general distribution of breast lesions diagnosed by cytology test at Eritrean National Health Laboratory. Methods This retrospective study was carried out on 905 symptomatic patients between the years 2013 and 2017 at Eritrean National Health Laboratory. Diagnosis was made by fine needle aspiration cytology in patients with palpable breast lump and in some patients direct smear was prepared from a nipple discharge. Statistical analysis was carried out using Statistical Package for the Social Sciences version 23. Results A total of 905 patients were included in the study, of whom 871 (96.24%) were females. The age range of patients was from 13 to 93 years with mean and standard deviation of 33 ± 14.9 years. Breast lump, occurring in 892 (98.56%), was the most frequent presenting symptom. Fibroadenoma and fibrocystic breast lesions were the most prevalent lesions accounting for approximately 40% and 15%, respectively. Malignant breast lesions were seen predominantly in females above the age of 40 years with the highest frequency observed in the age range between 51 and 60 years. Pearson Chi-squared test showed significant association between patients’ age above 40 years and the risk of having a malignant breast lesion (p < 0.001). The highest number of benign and malignant breast lesions was documented in 2014 with little fluctuation elsewhere in the study period. Conclusion Fine needle aspiration cytology is a procedure of choice for preoperative diagnosis in breast lesions mainly in a resource-limited settings. Our study identified the occurrence of malignant breast lesions in young women, which is of a paramount public health concern. Of note, significant proportion of patients were late to seek medical attention. Therefore, enhancement of community awareness regarding breast disease and implementation of screening programs are necessary to ameliorate the morbidity and mortality associated with the disease.

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Comparison of Ultrasonography and Fine Needle Aspiration Cytology in the Diagnosis of Malignant Breast Lesions

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2013/6493.3887 ◽

2013 ◽

Cited By ~ 1

Author(s):

Sunil Singh Lourembam

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Breast Lesions ◽

Aspiration Cytology ◽

Fine Needle ◽

Malignant Breast ◽

Needle Aspiration Cytology

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Role of Fine Needle Aspiration Cytology in Diagnosing Non-Malignant Breast Lesions

Saudi Journal of Pathology and Microbiology ◽

10.36348/sjpm.2019.v04i11.010 ◽

2019 ◽

Vol 04 (11) ◽

pp. 832-836

Author(s):

Shilpa M Shetty ◽

Priyanka Devagiri ◽

U S Dinesh

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Breast Lesions ◽

Aspiration Cytology ◽

Fine Needle ◽

Malignant Breast ◽

Needle Aspiration Cytology

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The Spectrum of Malignant Breast lesions by Fine Needle Aspiration Cytology in a Teaching Hospital

Tropical Journal of Pathology and Microbiology ◽

10.17511/jopm.2021.i04.05 ◽

2021 ◽

Vol 7 (4) ◽

pp. 181-187

Author(s):

Dr. Mallikarjun. A. Pattanashetti ◽

◽

Dr. Manika Alexander ◽

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Breast Diseases ◽

Breast Lesions ◽

Aspiration Cytology ◽

Early Management ◽

Fine Needle ◽

Malignant Breast ◽

Needle Aspiration Cytology

Background: Fine needle aspiration cytology (FNAC) is one of the preliminary tests done to detectmalignant breast lesions, which help in early detection and management. Studying the cytologyfeatures of various malignant breast diseases was the aim of this study. Methods: This study is across-sectional retrospective study conducted in the Department of Pathology from 2015 to 2020.Clinical details and cytology features were collected from the Department records. Results: A totalof 75 cases were collected during the study period. All the cases were females. The spectrum oflesions was composed of Ductal carcinoma followed by one point each of Mucinous carcinoma,Malignant Phyllodes tumour and Lobular Carcinoma. Conclusions: FNAC helps in rapid diagnosisand early management of malignant breast lesions.

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ASSESSMENT OF DIAGNOSTIC ACCURACY OF FINE NEEDLE ASPIRATION CYTOLOGY IN BENIGN AND MALIGNANT BREAST LESIONS

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i3.1187 ◽

2020 ◽

Vol 4 (3) ◽

Author(s):

Tanwi Singh ◽

Kalpana Chandra

Keyword(s):

Diagnostic Accuracy ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Large Population ◽

Needle Aspiration ◽

Breast Lesions ◽

Aspiration Cytology ◽

Fine Needle ◽

Malignant Breast ◽

Needle Aspiration Cytology

Increasing awareness, associated anxiety & stress among women who perceive every lump in breast as carcinoma, compels the patient to seek the medical advice. It is sometimes difficult to determine whether a suspicious lump is benign or malignant simply from clinical assessment and fine needle aspiration cytology (FNAC) is helpful in reaching definitive diagnosis. Accuracy in the diagnosis can be increased by multiple sampling of appropriate sites by ultrasonography guidance and/or mammographic localization. Breast cancer is the most common cancer in women all over India. Due to lack of awareness and almost non-existent breast screening practices, patients present with palpable breast cancers. Hence based on above findings the present study was planned for Assessment of Diagnostic Accuracy of Fine Needle Aspiration Cytology in Benign and Malignant Breast Lesions. The present study was planned in Department of Pathology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India. The present study was planned from duration of march 2019 to August 2019. In the present study 50 females with breast lesion were included and evaluated in the present study. The FNAC was performed in each patient by the technique of Martin and Ellis using 21-22G needle attached to 20 ml disposable syringe and smear prepared both wet fixed in 95% ethanol and air dried. All cytology smears were stained by May Grunwald Giemsa, Papanicolaou, and hematoxylin and eosin stain. It is highly useful in screening large population as it is simple, rapid, cost effective and reliable. FNAC has few limitations and biopsy is must in cases with suspicious and atypical lumps. FNAC serves as a compliment and not a substitute to the histopathology in such cases. So, it is concluded that FNAC should be used as a routine diagnostic procedure to maximize the availability of effective health care to patients with breast lesions. Keywords: Diagnostic Accuracy, Fine Needle Aspiration, Cytology, Benign, Malignant Breast Lesions, etc.

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