Pattern and Outcome of Acute Appendicitis: Observational Prospective Study from a Teaching Hospital, Addis Ababa, Ethiopia

In a five-year prospective study,1188 consecutive adult patients were admitted and treated for acute generalized peritonitis at the Surgical Emergency Unit of the Komfo Anokye Teaching Hospital, Kumasi, Ghana. Appendicitis and typhoid ileal perforation were the commonest causes, occurring in 43.1% and 35.1% of patients, respectively. Other conditions (gastroduodenal perforations, ruptured abscesses, traumatic bowel perforations and amoebic colonic perforations) accounted for fewer than 25% of cases. This paper notes that acute appendicitis and typhoid perforation remain the leading causes of peritonitis in Ghana. Compared with previous series, the importance of appendicitis in acute peritonitis has diminished. The complications of communicable diseases now cause peritonitis more commonly than 35 years ago. This may reflect deteriorating conditions of sanitation and housing during the intervening period.

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Anticoagulant Utilization Evaluation in a Tertiary Care Teaching Hospital: An Observational Prospective Study in Medical in Patients

Indian Journal of Pharmacy Practice ◽

10.5530/ijopp.8.2.3 ◽

2015 ◽

Vol 8 (2) ◽

pp. 61-66 ◽

Cited By ~ 1

Author(s):

Vijay Singh ◽

Krishnappa Gopinath ◽

Amirali Behzadpour ◽

Neelathahalli Kasturiranagan Meera

Keyword(s):

Prospective Study ◽

Teaching Hospital ◽

Tertiary Care ◽

Tertiary Care Teaching Hospital ◽

Care Teaching ◽

Observational Prospective Study

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Evaluation of Serum Bilirubin as a Predictive Marker for Simple and Complicated Appendicitis in Sulaimani Emergency Teaching Hospital

Kurdistan Journal of Applied Research ◽

10.24017/science.2018.2.3 ◽

2018 ◽

pp. 15-20

Author(s):

Seerwan Hama Shareef ◽

Dara Ahmed Mohammed ◽

Goran Ameer Ahmed

Keyword(s):

Acute Appendicitis ◽

Prospective Study ◽

Teaching Hospital ◽

Serum Bilirubin ◽

Complicated Appendicitis ◽

White Blood Count ◽

Total Serum ◽

Lower Sensitivity ◽

Specific Marker ◽

Suspected Appendicitis

Diagnosis of acute appendicitis can be challenging in some cases as the differentials can be exhaustive. Previous studies have demonstrated that hyperbilirubinemia is a more specific marker for appendicitis than white blood count (WBC) and C-reactive protein (CRP), but this investigation is still not commonly used in the diagnostic workup of appendicitis. This prospective study aims to evaluate serum bilirubin as a laboratory marker for simple and complicated appendicitis. We also investigated the diagnostic value of bilirubin in acute appendicitis and compared it with the WBC. In this prospective study, all patients who underwent appendicectomy at the Sulaimani Emergency Teaching Hospital between 1st November 2016 to 1st January 2017 were included. Preoperative total serum bilirubin was measured and compared with the final histopathology report. Patients were divided into 3 groups: non-inflamed appendix, simple appendicitis and complicated appendicitis. One hundred and 75 patients were analysed, 90 of them were females and 85 were males. Hyperbilirubinemia was found in 63% of patients with complicated appendicitis (p=0.001). Mean of bilirubin was significantly different between patients with complicated appendicitis and non-complicated appendicitis (1.101 vs 0.75 mg/dl; p= 0.0017). Bilirubin had a higher specificity (85%) than WBC (36%), but a lower sensitivity (63% vs 89%) for differentiating complicated appendicitis. Patients with suggestive features of acute appendicitis and raised serum bilirubin indicate a complicated case requiring early intervention to prevent peritonitis and septicaemia. Hyperbilirubinemia is a good indicator for complicated appendicitis and serum bilirubin measurement can be included in the work up of patients with suspected appendicitis.

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