<p>Baseline Predictive Factors of Visual Outcome and Persistence of Subretinal Fluid Based on Morphologic Changes in Spectral Domain Optical Coherence Tomography in Patients with Idiopathic Central Serous Chorioretinopathy</p>

Purpose: To identify prognostic factors for the visual outcome for patients with macula-off rhegmatogenous retinal detachment (RRD). Methods: The medical records of 27 patients (27 eyes) with macula-off RRD were retrospectively investigated. In addition to clinical characteristics, spectral-domain optical coherence tomography (SD OCT) images were analyzed. Results: The central foveal thickness at baseline was 923 ± 499.5 µm, and the mean height of the subretinal fluid was 697.8 ± 463.6 µm. Dropout of backreflection at the fovea was detected on preoperative SD OCT in 8 patients (29.6%). The external limiting membrane was disrupted in 5 patients (18.5%) as was the photoreceptor integrity in 9 patients (33.3%) at 12 months. On multiple regression analysis, backreflection integrity was the only predictive factor for postoperative visual outcome (B = 0.179, p = 0.020). Conclusions: Backreflection integrity on preoperative SD OCT seems to be helpful in predicting the postoperative visual outcome in macula-off RRD patients.

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Morphologic Changes in Acute Central Serous Chorioretinopathy Using Spectral Domain Optical Coherence Tomography

Korean Journal of Ophthalmology ◽

10.3341/kjo.2012.26.5.347 ◽

2012 ◽

Vol 26 (5) ◽

pp. 347 ◽

Cited By ~ 24

Author(s):

Hyung Chan Kim ◽

Won Bin Cho ◽

Hyewon Chung

Keyword(s):

Optical Coherence Tomography ◽

Central Serous Chorioretinopathy ◽

Spectral Domain ◽

Optical Coherence ◽

Acute Central Serous Chorioretinopathy ◽

Morphologic Changes

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Central serous chorioretinopathy imaging biomarkers

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2020-317422 ◽

2020 ◽

pp. bjophthalmol-2020-317422

Author(s):

Sumit Randhir Singh ◽

Claudio Iovino ◽

Dinah Zur ◽

Dua Masarwa ◽

Matias Iglicki ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Regression Analysis ◽

Central Serous Chorioretinopathy ◽

Subretinal Fluid ◽

Visual Outcome ◽

Multivariate Regression Analysis ◽

Imaging Biomarkers ◽

Optical Coherence ◽

Linear Extent ◽

Good Visual Outcome

PurposeTo identify the factors predicting the visual and anatomical outcomes in eyes with central serous chorioretinopathy (CSCR) through 12 months.MethodsPatients with diagnosis of CSCR, either acute or chronic, were included in this multicentric, retrospective study. Demographic factors; systemic risk factors; central macular thickness (CMT), subfoveal choroidal thickness (SFCT), linear extent of ellipsoid zone (EZ) and interdigitation zone damage on optical coherence tomography; details of leak on fluorescein angiography and indocyanine green angiography were included as predictors of anatomical and visual outcomes. Regression analysis was performed to correlate the changes in best corrected visual acuity (BCVA) and resolution of disease activity.ResultsA total of 231 eyes of 201 patients with a mean age (49.7±11.8 years) were analysed. A total of 97 and 134 eyes were classified as acute and chronic CSCR. BCVA (0.35±0.31 to 0.24±0.34; p<0.001), baseline optical coherence tomography (OCT) parameters including CMT (p<0.001), subretinal fluid (SRF) height (p<0.001) and SFCT (p=0.05) showed a significant change through 12 months. Multivariate regression analysis showed change in CMT (p≤0.01) and SRF height at baseline (p=0.05) as factors predictive of good visual outcome. Logistic regression analysis revealed changes in both CMT (p=0.009) and SFCT (p=0.01) through 12 months to correlate with the resolution of disease.ConclusionOCT parameters such as changes in both CMT and SFCT along with subfoveal EZ damage can be predictive of disease resolution whereas changes in CMT and baseline SRF height correlate well with changes in BCVA through 12 months.

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Time-Periodic Characteristics in the Morphology of Idiopathic Central Serous Chorioretinopathy Evaluated by Volume Scan Using Spectral-Domain Optical Coherence Tomography

American Journal of Ophthalmology ◽

10.1016/j.ajo.2012.02.031 ◽

2012 ◽

Vol 154 (2) ◽

pp. 366-375.e4 ◽

Cited By ~ 42

Author(s):

In Seok Song ◽

Yong Un Shin ◽

Byung Ro Lee

Keyword(s):

Optical Coherence Tomography ◽

Central Serous Chorioretinopathy ◽

Spectral Domain ◽

Optical Coherence ◽

Time Periodic

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Subretinal Fluid Optical Density and Spectral-Domain Optical Coherence Tomography Characteristics for the Diagnosis of Circumscribed Choroidal Hemangioma

Ophthalmologica ◽

10.1159/000492948 ◽

2018 ◽

Vol 241 (4) ◽

pp. 195-201 ◽

Cited By ~ 1

Author(s):

Dinah Zur ◽

Shahar Frenkel ◽

Ari Leshno ◽

Matias Iglicki ◽

Noa Ben-Artzi Cohen ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Optical Density ◽

Subretinal Fluid ◽

Spectral Domain ◽

Optical Coherence ◽

Choroidal Hemangioma

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Spectral-Domain Optical Coherence Tomography-Based Morphofunctional Characterization of Dome-Shaped Maculopathy in Indian Population

Journal of Ophthalmology ◽

10.1155/2020/8869455 ◽

2020 ◽

Vol 2020 ◽

pp. 1-7

Author(s):

Naresh Babu Kannan ◽

Sagnik Sen ◽

Prithviraj Udaya ◽

Obuli Ramachandran ◽

Kim Ramasamy

Keyword(s):

Optical Coherence Tomography ◽

Indian Population ◽

Subretinal Fluid ◽

Cross Sectional Study ◽

Spectral Domain ◽

Dome Height ◽

Optical Coherence ◽

Cross Sectional ◽

Sd Oct

Purpose. To study the clinicodemographic profile of dome-shaped maculopathy (DSM) eyes in the Indian population and characterization using spectral-domain optical coherence tomography (SD-OCT). Methods. This observational cross-sectional study included 25 eyes of 14 patients diagnosed with DSM. All eyes underwent SD-OCT for characterization of the dome profile and also to measure central macular thickness (CMT), subfoveal choroidal thickness (SFCT), and dome height (DH) and to detect the presence of subretinal fluid (SRF). Results. The mean age of patients was 48.36 ± 14.23 years (range, 28–65 years). Eleven patients had bilateral involvement. Mean axial length of all eyes was 24.25 ± 1.95 mm and mean spherical equivalent −4.23 ± 3.79 DS. Overall, 11/25 eyes (44%) had round domes, 9/25 eyes (36%) had horizontal domes, and 5/25 eyes (20%) had vertical domes, with a mean dome height at fovea of 500.54 ± 291.58 µm. Vertical domes had higher DH compared to horizontal or combined domes p = 0.02 . Six eyes (6/25, 24%) showed the presence of SRF; 60% of vertical domes had SRF, and 22.2% of horizontal domes had SRF. The eyes having SRF had significantly higher CMT p = 0.017 and DH p = 0.001 , especially in horizontal domes p = 0.023 . The eyes with thicker SFCT tended to have higher DH and poorer visual acuity. Conclusion. Indian DSM eyes may have relatively lesser amounts of myopia. Choroidal thickening may play a role in development of DSM and may also be related to development of subretinal fluid in such eyes.

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