Wilms' tumor may be a rare presentation of ovarian neoplasms in girls

Brenner tumors are rare ovarian tumors accounting for 2-3% of all ovarian neoplasms and about 2% of these tumors are borderline (proliferating) or malignant. These tumors are commonly seen in 4th-8th decades of life with a peak in late 40s and early 50s. Benign Brenner tumors are usually small, <2cm in diameter and often detected incidentally during surgery or on pathological examination. Authors report a case of a large, calcified benign Brenner tumor in a 55-year-old postmenopausal woman who presented with complaint of abdominal pain and mass in abdomen. Imaging revealed large complex solid cystic pelvic mass -peritoneal fibrosarcoma. She underwent laparotomy which revealed huge Brenner tumor weighing 9kg arising from left uterine cornual end extending up to epigastric region. Myomectomy and hysterectomy with bilateral salphingo oophorectomy, omentectomy done and the specimen was sent for histopathological and immunohistochemistry study which revealed benign Brenner tumor. Brenner tumors are rare ovarian neoplasms accounting for 2-3% of all ovarian tumors. Benign Brenner tumors are usually small and solid whereas borderline and malignant Brenner tumors are usually larger and cystic with solid areas. But it is possible to have a completely benign large Brenner tumor. Therefore, benign nature of the lesion should not be excluded even when the ovarian tumor is very large.

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Pedunculated and obstructive Wilms' tumor: A rare presentation in a 2 year-old male

Urology Case Reports ◽

10.1016/j.eucr.2018.06.004 ◽

2018 ◽

Vol 20 ◽

pp. 38-40

Author(s):

Leor T. Arbel ◽

Morris Jessop ◽

Osama Al-Omar

Keyword(s):

Wilms Tumor ◽

Rare Presentation

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Synchronous bilateral Wilms’ tumor with liver metastasis

BMC Urology ◽

10.1186/s12894-021-00859-8 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Senai Goitom Sereke ◽

Abdirahman Omar Sahal ◽

Vincent Mboizi ◽

Felix Bongomin

Keyword(s):

Liver Metastasis ◽

Wilms Tumor ◽

Tumor Board ◽

Rare Presentation ◽

Early Palliative Care ◽

Palliative Intent ◽

History Of ◽

Solid Lesions ◽

Evidence Based Guidelines ◽

Bilateral Wilms Tumor

Abstract Background Wilms’ tumor (nephroblastoma) is mostly unilateral; however, bilateral Wilms’ tumors are seen in about 5–8% of patients. This can be synchronous or metachronous. It is uncommon to get liver metastasis from bilateral Wilms’ tumor. Case presentation An 8-year-old male Ugandan presented with a history of abdominal swelling and flank pains for 1 year. There was no history of hematuria. Both ultrasound and computed tomography of the abdomen demonstrated multiple solid lesions in both kidneys and a huge solid mass in segments V, VI, VII and VIII of the liver. Histological examination of renal biopsy specimen was favorable for chemotherapeutic regimens. However, following a multidisciplinary tumor board consensus, a nephron-sparing surgery was deemed unsuitable, and he was managed conservatively with chemotherapy (adriamycin and vincristine) with a palliative intent. Conclusions Metastatic bilateral Wilms’ tumor has a particularly poor prognosis. There are no clear evidence-based guidelines for the management of this rare presentation. This patient benefited from early palliative care and symptom management.

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