scholarly journals A rare presentation of benign Brenner tumor of ovary: a case report

2018 ◽  
Vol 7 (7) ◽  
pp. 2971
Author(s):  
Sumathi Periasamy ◽  
Subha Sivagami Sengodan ◽  
Devipriya . ◽  
Anbarasi Pandian
Keyword(s):  
Abdominal Pain ◽  
Ovarian Tumor ◽  
Ovarian Neoplasms ◽  
Pelvic Mass ◽  
Ovarian Tumors ◽  
Pathological Examination ◽  
Rare Presentation ◽  
Brenner Tumor ◽  
Benign Nature ◽  
Brenner Tumors

Brenner tumors are rare ovarian tumors accounting for 2-3% of all ovarian neoplasms and about 2% of these tumors are borderline (proliferating) or malignant. These tumors are commonly seen in 4th-8th decades of life with a peak in late 40s and early 50s. Benign Brenner tumors are usually small, <2cm in diameter and often detected incidentally during surgery or on pathological examination. Authors report a case of a large, calcified benign Brenner tumor in a 55-year-old postmenopausal woman who presented with complaint of abdominal pain and mass in abdomen. Imaging revealed large complex solid cystic pelvic mass -peritoneal fibrosarcoma. She underwent laparotomy which revealed huge Brenner tumor weighing 9kg arising from left uterine cornual end extending up to epigastric region. Myomectomy and hysterectomy with bilateral salphingo oophorectomy, omentectomy done and the specimen was sent for histopathological and immunohistochemistry study which revealed benign Brenner tumor. Brenner tumors are rare ovarian neoplasms accounting for 2-3% of all ovarian tumors. Benign Brenner tumors are usually small and solid whereas borderline and malignant Brenner tumors are usually larger and cystic with solid areas. But it is possible to have a completely benign large Brenner tumor. Therefore, benign nature of the lesion should not be excluded even when the ovarian tumor is very large.

scholarly journals A Rare Case of Bilateral Malignant Brenner Tumors of the Ovaries Associated with Peritoneal Effusion

2020 ◽  
Author(s):  
Jianing Tong ◽  
Jianmin Niu ◽  
Qiaoyun Li ◽  
Li Hu ◽  
Hui Zhang
Keyword(s):  
Preoperative Diagnosis ◽  
Vaginal Bleeding ◽  
Rare Case ◽  
Clinical Symptoms ◽  
Ovarian Tumors ◽  
Case Presentation ◽  
Brenner Tumor ◽  
Peritoneal Effusion ◽  
Brenner Tumors ◽  
The Masses

Abstract Background: Malignant ovarian Brenner tumors are extremely rare worldwide, accounting for only 1% of malignant ovarian tumors. Their clinical symptoms and pathology are complex and erratic, and the images are mostly non-specific. This poses difficulties in preoperative diagnosis and distinguishing them from other cystic solid ovarian tumors. Here this study has reported on a case of bilateral malignant ovarian Brenner tumor with peritoneal effusion. Case presentation: A 54-year-old woman presented with intermittent vaginal bleeding for more than two months and abdominal pain for one month. Two hard mass of five centimeters with poor movement could be touched at each side of the ovarian areas. The CT findings indicated the presence of two large cystic and solid masses in both adnexal regions. The operation had watched the size of the masses in the bilateral ovarian was both 6cmx6cmx5cm and their surface ulceration showed rotten fleshy tissue. After the operation, combined with morphological and immunohistochemical features, the ovarian specimens were consistent with bilateral ovarian malignant Brenner tumors.Conclusions: Although the incidence of bilateral malignant OBT is extremely low and this disease is extremely rare clinically, the gynecologists should be more informed of its diagnosis and treatment.

scholarly journals Giant Ovarian Tumor Presenting as a Huge Abdomino-Pelvic Mass in a Teenage Girl: A Case Report

2021 ◽  
Vol 39 (2) ◽  
pp. 137-141
Author(s):  
Muhammad Jamaluddin ◽  
Hajrah Hilal Ahmed
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Ovarian Tumor ◽  
Abdominal Cavity ◽  
Lower Abdominal Pain ◽  
Pelvic Mass ◽  
Interesting Case ◽  
Ovarian Cysts ◽  
Teenage Girl ◽  
Common Causes

Ovarian cysts are common causes of lower abdominal pain and abdominal distention in females. While most of them are benign and rarely grow immensely to achieve a huge size, they may be neoplastic in origin, reaching enormous dimensions with minimum or without raising any symptoms.Here, we present an interesting case of a 19-year-old female,who presented with huge abdominal swelling and pain in whole abdomen from whom a 9.1 kg borderline mucinous ovarian cyst, occupying the whole abdominal cavity was removed. J Bangladesh Coll Phys Surg 2021; 39(2): 137-141

scholarly journals Bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma: a case report

2019 ◽  
Vol 8 (5) ◽  
pp. 2122
Author(s):  
Natasha Mittal ◽  
Bhaskar Das ◽  
Seema Manuja ◽  
Renu Gupta
Keyword(s):  
Incidental Finding ◽  
Transitional Cell ◽  
Mucinous Cystadenoma ◽  
Pathological Examination ◽  
Benign Tumors ◽  
Surgical Removal ◽  
Brenner Tumor ◽  
Brenner Tumors ◽  
Mucinous Cystadenomas ◽  
Transitional Cell Tumors

Brenner tumors are rare ovarian tumors, which are a subgroup of transitional cell tumors of ovary. Most of these tumors are benign presenting as incidental unilateral masses in postmenopausal age group. Only 5-7% cases are bilateral. These tumors are mostly small, solid and asymptomatic, seen commonly in association with mucinous cystadenomas of ovary. In such cases they may attain a massive size. Specific diagnosis of Brenner tumor is difficult using imaging studies and can be definitely diagnosed only on pathological examination. Surgical removal is usually curative for benign tumors. We present a rare case of bilateral Brenner tumor of ovary with associated unilateral mucinous cystadenoma in which bilateral Brenner tumor was a rare incidental finding on pathological examinatio

Mixed Ovarian Tumor Composed of Brenner Tumor and Adult-Type Granulosa Cell Tumor: A Case Report of a Very Rare Mixed Ovarian Tumor and a Review of the Literature

2017 ◽  
Vol 26 (4) ◽  
pp. 382-387
Author(s):  
Judit Tamás ◽  
Ildikó Vereczkey ◽  
Erika Tóth ◽  
Erzsébet Csernák ◽  
Katalin Purcsi ◽  
...  
Keyword(s):  
Case Report ◽  
Granulosa Cell ◽  
Ovarian Tumor ◽  
Granulosa Cell Tumor ◽  
Cell Tumor ◽  
Ovarian Tumors ◽  
Review Of The Literature ◽  
Adult Type ◽  
Histologic Subtype ◽  
Brenner Tumor

A combination of ovarian tumors with the same histogenetic origin but different histologic subtype is relatively common, whereas a co-occurrence of tumors with different histogenetic origin is rare. We report a case of mixed ovarian tumor composed of Brenner tumor and adult-type granulosa cell tumor, a combination that to the best of our knowledge has not been reported in the literature until now.

Brenner tumors

2021 ◽  
Author(s):  
Filipa de Sousa Costeira ◽  
Ana Félix ◽  
Teresa Margarida Cunha
Keyword(s):  
Differential Diagnosis ◽  
Ovarian Neoplasms ◽  
Fibrous Tissue ◽  
Ovarian Neoplasm ◽  
Imaging Features ◽  
The Past ◽  
Dense Fibrous Tissue ◽  
Brenner Tumor ◽  
Brenner Tumors ◽  
Asymptomatic Women

Brenner tumors are rare ovarian neoplasms composed of ovarian transition cells surrounded by dense fibrous tissue. Most of them are small tumors (<2 cm), detected incidentally in asymptomatic women. Its predominantly fibrous content results in relatively low signal on T2 weighted images, establishing differential diagnosis with ovarian fibroma and thecoma. Their imaging features are very similar, the differentiation is based on secondary characteristics, such as signs or symptoms of estrogen excess and the presence of a second ovarian neoplasm, which has been reported in up to 30% of patients with Brenner tumor. Although originally thought to be universally benign, there have been scattered reports in the past decades of borderline and malignant forms of Brenner tumors.

scholarly journals Demons meigs’ syndrome secondary to begnin brenner tumor with high ca125 plasmatic level: first case described in kara teaching hospital

2019 ◽  
pp. 08-12
Author(s):  
Aboubakari AS ◽  
Dossouvi T ◽  
Logbo-Akey KE ◽  
Ajavon DR ◽  
Dagbé M ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Teaching Hospital ◽  
Ovarian Tumor ◽  
Pelvic Mass ◽  
Abdominal Distension ◽  
Abdominal Ultrasound ◽  
First Case ◽  
Brenner Tumor ◽  
Benign Ovarian Tumor ◽  
Plasmatic Level

To report the first case of Demons-Meigs’ syndrome secondary to benign Brenner tumor with high CA125 plasmatic level managed in kara teaching hospital. A 40-year-old female patient was admitted with a 6-month history of abdominal distension. Clinical examination found abdomino-pelvic mass and declive dullness. Abdominal ultrasound found heterogeneous abdomino-pelvic mass of 180 mm in length and a large free ascites. Pelvic computorized tomography scan found heterogeneous extra-uterine mass of 180 mm in length, large ascites without pelvic or lombo-aortic lymphadenopathy or tumoral extension. Front thorax X-ray found bilateral pleural effusion; CA125 plasmatic level was 1138 IU/ml. Median laparotomy allow to aspire 2 liters of ascitic fluid and to perform left adnexectomy. Histological examination of surgery sample diagnosed begnin ovary Brenner tumor. Outcome after surgery was without complications with disappearance of ascites and pleural effusion, and CA125 plasmatic level back to normal value. Demons-Meigs’ syndrome is a rare benign ovarian tumor whose symptoms looks like ovarian cancer. Its fundamental characteristic is the disappearance of symptoms after ovarian tumor removal.

scholarly journals Application value of color doppler ultrasound and ultrasound contrast in the differential diagnosis of ovarian tumor

2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Haijing Zhang ◽  
Jinming Wang ◽  
Rui Guo
Keyword(s):  
Differential Diagnosis ◽  
Doppler Ultrasound ◽  
Ovarian Tumor ◽  
Malignant Tumors ◽  
Color Doppler ◽  
Color Doppler Ultrasound ◽  
Ovarian Tumors ◽  
Pathological Examination ◽  
Ultrasound Contrast ◽  
Sensitivity Specificity

Objective: To study the value of color Doppler ultrasound and ultrasound contrast in differential diagnosis of ovarian tumors. Methods: Ninety-six patients with ovarian tumors who were treated in our hospital from May 2017 to July 2018 and confirmed by pathological examination were selected as the research subjects. All patients were examined by color Doppler ultrasound and ultrasound contrast. The sensitivity, specificity and accuracy of the two methods were compared, and the parameters of ultrasound contrast in the diagnosis of benign and malignant tumors were observed and compared. Results: The sensitivity, specificity and accuracy of ultrasound contrast in the diagnosis of ovarian tumors were higher than those of color Doppler ultrasound (P<0.05). There were significant differences in the time of initiation enhancement, time to peak and perfusion intensity in the diagnosis of benign and malignant lesions by ultrasound contrast (P<0.05). Conclusion: In the differential diagnosis of ovarian tumors, ultrasound contrast has more advantages than color Doppler ultrasound in displaying the blood perfusion information of tumors. It has high diagnostic accuracy and clinical application value. doi: https://doi.org/10.12669/pjms.36.2.847 How to cite this:Zhang H, Wang J, Guo R. Application Value of color doppler ultrasound and ultrasound contrast in the differential diagnosis of ovarian tumor. Pak J Med Sci. 2020;36(2):---------. doi: https://doi.org/10.12669/pjms.36.2.847 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Histopathological pattern of ovarian neoplasms in Sub-Himalayan belt of rural India: a four-year study from a tertiary care teaching hospital

2017 ◽  
Vol 6 (12) ◽  
pp. 5448
Author(s):  
Manupriya Sharma ◽  
Anjali Soni ◽  
Rashmi Kaul
Keyword(s):  
Ovarian Tumor ◽  
Ovarian Neoplasms ◽  
Malignant Tumors ◽  
Germ Cell Tumors ◽  
Ovarian Tumors ◽  
Rural India ◽  
Benign Tumors ◽  
Age Group ◽  
Epithelial Tumors ◽  
Himalayan Belt

Background: Ovarian tumors are one of the ubiquitous and common forms of neoplasms in women. The aim of the study was to understand the pattern of benign and malignant ovarian neoplasms and their distribution in different age groups in rural population of India.Methods: A retrospective study conducted in the Department of Pathology in close collaboration with Department of Obstetrics and Gynecology, Dr. Rajendra Prasad Government Medical College, Kangra at Tanda (HP), India. All the patients irrespective of age group who were operated for ovarian neoplasms (benign or malignant) were included in this retrospective analysis over duration of four years (2013 to 2016). “WHO classification system” was used, for classification of all these ovarian tumors. The incidence of these tumors with respect to age group was also studied.Results: During the study period (2013-2016), there were a total of 242 surgeries for ovarian neoplasms. Of these, majority of the tumours were benign 184 (76%), but an alarming number of women had malignant ovarian tumours 51 (21%), remaining 7 (3%) cases were borderline. Age wise distribution was 7% (16/242) in less than 20 years age, 19% (46/242) in 20-30 years age, 29% (69/242) in 30-40 years age group, 24% (59/242) in 40-50 years and remaining 21% (52/242) in more than 50 years age group. Pre-dominantly benign tumors were surface epithelial tumors (serous/ mucinous cystadenoma), germ cell tumors (mature cystic teratoma) and endometrioma. Major malignant tumors were surface epithelial tumors (serous/mucinous cystadeno-carcinoma), and germ cell tumors (dysgerminoma, immature teratoma).Conclusions: In this sub-Himalayan belt of rural India, the incidence of benign ovarian tumors was 76%. Borderline ovarian tumors were seen in 3% cases and the remaining 21% cases were malignant ones. Even though benign tumors were the commonest for each age group, however as the age of women increased the proportion of malignant tumors in them increased. Surface epithelial tumors are the most common class of tumors in both benign and malignant tumors. Serous cystadenoma is the most common ovarian tumor overall as well as most common benign tumor whereas serous cystadeno-carcinoma is most common malignancy. Stromal ovarian tumor (one case) is a rarity. Only one woman had bilateral ovarian tumor.  

scholarly journals Hyperandrogenism in a Postmenopausal Woman Secondary to Testosterone Secreting Ovarian Stromal Tumor with Acoustic Schwannoma

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Bindu Gandrapu ◽  
Preeyanka Sundar ◽  
Brian Phillips
Keyword(s):  
Postmenopausal Woman ◽  
Ovarian Tumor ◽  
Ovarian Neoplasms ◽  
Ovarian Tumors ◽  
Stromal Tumor ◽  
Acoustic Schwannoma

Androgen-secreting ovarian neoplasms are rare ovarian tumors that present with hirsutism and virilization which may manifest as severe alopecia, deepening of voice, and clitoromegaly. Most often, ovarian tumors are found to be very small or even undetectable. In such cases, bilateral salpingo-oophorectomy should be performed after ruling out other causes of high androgens. We present a 63-year-old postmenopausal woman with clinically and radiologically undetectable testosterone-secreting ovarian tumor, which was later on detected on biopsy.

scholarly journals Mayer-Rokitansky-Kuster-Hauser syndrome and ovarian benign teratoma: a case report

2020 ◽  
Vol 9 (2) ◽  
pp. 815
Author(s):  
Cassou R. Adjoby ◽  
Soh V. Koffi ◽  
Denis Effoh ◽  
Eleonore Gbary Lagaud ◽  
Christian H. Alla ◽  
...  
Keyword(s):  
Ovarian Tumor ◽  
Autosomal Dominant ◽  
Pelvic Mass ◽  
Pathological Examination ◽  
Fallopian Tubes ◽  
Medical Assistance ◽  
Normal Appearance ◽  
First Case ◽  
Gestational Surrogacy ◽  
Benign Teratoma

Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) is an unknown congenital etiology disorder characterized by agenesia or hypoplasia of the Müller ductal system, including the upper vagina, uterus and fallopian tubes. The occurrence of an associated ovarian tumor is rare, with fewer than 20 cases reported to date according to the literature. We report the case of a 14-year-old girl, virgin, who had not yet seen her menarche, complaining of an abdomino-pelvic mass associated with pain. The ultrasound performed revealed a large left ovarian tumor and an absence of uterus. The indication of a laparotomy confirmed the ovarian mass and a complete absence of uterus associated with vaginal hypoplasia. The contralateral ovary was present, and of normal appearance. The pathological examination was in favor of a mature benign multi-tissular teratoma. This is the first case described in our service. The mode of transmission of this entity appears to be autosomal dominant with low penetrance and variable expressivity, suggesting that the incidence of this syndrome is likely underestimated. With the development of techniques of medical assistance to procreation, maternity remains possible, particularly through gestational surrogacy.

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