Early results of surgery for aortic valve disease in patients with severe left ventricular dysfunction
<p><strong>Aim.</strong> This study aimed to analyse the early results of aortic valve replacement in patients with severe left ventricular dysfunction: i.e. a left ventricle ejection fraction (LVEF) ≤30%.<br /><strong>Methods.</strong> This retrospective study included 145 adult patients with isolated aortic valve disease and LVEF ≤30% who underwent aortic valve replacement from 2005 to 2019 at our institution. Patients who required any concomitant or redo surgery were excluded from the study.<br /><strong>Results.</strong> There were three perioperative deaths (in-hospital mortality, 2.1%) due to multiple organ failure syndrome (two patients) or acute heart failure (one patient). Postoperative heart failure was the prevailing non-lethal complication (73% of cases). Other complications occurred less frequently: nine patients (6.2%) had acute kidney injury (four of whom required hemodiafiltration), one patient (0.7%) suffered a stroke, six patients (4%) required chest re-exploration for bleeding and two patients (1.4%) experienced sternal infection of the surgical wound. Patient LVEF improved significantly from 22.6% ± 5.3% to 35.8% ± 11.0% postoperatively (a 37% mean increase; p = 0.02), and most patients (73%) were classified as New York Heart Association class I–II by the time of discharge.<br /><strong>Conclusion.</strong> Our study showed excellent results of surgery for aortic valve disease in patients with severe left ventricular dysfunction. Postoperatively, there was a marked increase in LVEF and significant clinical improvement.<br /><br />Received 1 May 2020. Revised 12 May 2020. Accepted 18 May 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and design: S.S. Babeshko, K.O. Barbukhatti, V.A. Porkhanov<br />Data collection and analysis: S.S. Babeshko, D.I. Shumkov<br />Drafting the article: S.S. Babeshko, Y.P. Samurganov<br />Statistical analysis: S.S. Babeshko, D.I. Shumkov<br />Critical revision of the article: S.S. Babeshko, Y.P. Samurganov, K.O. Barbukhatti<br />Final approval of the version to be published: S.S. Babeshko, Y.P. Samurganov, D.I. Shumkov, K.O. Barbukhatti, V.A. Porkhanov</p>