587 Echocardiographic markers for the detection of geometric remodelling and the frontier of reversible or irreversible systolic left ventricular dysfunction in patients with aortic valve disease

1999 ◽  
Vol 1 ◽  
pp. S96-S96
Author(s):  
T FORSTER ◽  
B FELKAI ◽  
E NAGY ◽  
K HAVASI ◽  
T SZARAZAJTAI
Keyword(s):  
Aortic Valve ◽  
Left Ventricular Dysfunction ◽  
Aortic Valve Disease ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Valve Disease

scholarly journals Early results of surgery for aortic valve disease in patients with severe left ventricular dysfunction

2020 ◽  
Vol 24 (2) ◽  
pp. 63
Author(s):  
S. S. Babeshko ◽  
Yu. P. Samurganov ◽  
D. I. Shumkov ◽  
K. O. Barbukhatti ◽  
V. A. Porkhanov
Keyword(s):  
Aortic Valve ◽  
Left Ventricular Dysfunction ◽  
Conflict Of Interest ◽  
Aortic Valve Disease ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Valve Disease ◽  
Severe Left Ventricular Dysfunction ◽  
Early Results ◽  
Results Of Surgery

<p><strong>Aim.</strong> This study aimed to analyse the early results of aortic valve replacement in patients with severe left ventricular dysfunction: i.e. a left ventricle ejection fraction (LVEF) ≤30%.<br /><strong>Methods.</strong> This retrospective study included 145 adult patients with isolated aortic valve disease and LVEF ≤30% who underwent aortic valve replacement from 2005 to 2019 at our institution. Patients who required any concomitant or redo surgery were excluded from the study.<br /><strong>Results.</strong> There were three perioperative deaths (in-hospital mortality, 2.1%) due to multiple organ failure syndrome (two patients) or acute heart failure (one patient). Postoperative heart failure was the prevailing non-lethal complication (73% of cases). Other complications occurred less frequently: nine patients (6.2%) had acute kidney injury (four of whom required hemodiafiltration), one patient (0.7%) suffered a stroke, six patients (4%) required chest re-exploration for bleeding and two patients (1.4%) experienced sternal infection of the surgical wound. Patient LVEF improved significantly from 22.6% ± 5.3% to 35.8% ± 11.0% postoperatively (a 37% mean increase; p = 0.02), and most patients (73%) were classified as New York Heart Association class I–II by the time of discharge.<br /><strong>Conclusion.</strong> Our study showed excellent results of surgery for aortic valve disease in patients with severe left ventricular dysfunction. Postoperatively, there was a marked increase in LVEF and significant clinical improvement.<br /><br />Received 1 May 2020. Revised 12 May 2020. Accepted 18 May 2020.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> Authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and design: S.S. Babeshko, K.O. Barbukhatti, V.A. Porkhanov<br />Data collection and analysis: S.S. Babeshko, D.I. Shumkov<br />Drafting the article: S.S. Babeshko, Y.P. Samurganov<br />Statistical analysis: S.S. Babeshko, D.I. Shumkov<br />Critical revision of the article: S.S. Babeshko, Y.P. Samurganov, K.O. Barbukhatti<br />Final approval of the version to be published: S.S. Babeshko, Y.P. Samurganov, D.I. Shumkov, K.O. Barbukhatti, V.A. Porkhanov</p>

Abstract 9947: Predictors of Left Ventricular Dysfunction After Aortic Valve Replacement in Patients With Mixed Aortic Valve Disease

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Alexander Egbe ◽  
Joeseph Poterucha ◽  
Carole Warnes
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Valve Replacement ◽  
Left Ventricular Dysfunction ◽  
Aortic Valve Disease ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Group 2 ◽  
Group 1

Objectives: Predictors of left ventricular dysfunction (LVD) after aortic valve replacement (AVR) in mixed aortic valve disease (MAVD) have not been studied. Objective was to determine prevalence and predictors of early and late LVD at 1 and 5 years post-AVR. Methods: Retrospective review of 247 patients (Age 63±8 years, males 81%) with moderate/severe MAVD who underwent AVR at the Mayo Clinic from 1994-2013. Only patients with follow-up data at 1 year post AVR were included (n=239). Cohort divided into 3 groups based on data collected prior to AVR, 1 and 5 years post AVR. LVD was defined as ejection fraction <50%. Results: LVD was present in 11/239 at baseline. At 1-year post AVR, 181 had normal EF (group 1) while 58/239 (24%) had early LVD (group 2). Predictors of LVD were atrial fibrillation (hazard ratio [HR] 1.83 confidence interval [CI] 1.59-1.98, p=0.001), age >70 years (HR: 3.12, CI: 2.33-4.18, p= <0.0001), CABG (HR: 2.17, CI: 2.24-5.93, p= <0.0001), and severe MAVD pre-operatively (HR: 2.87, CI: 2.33-3.17, p= 0.01), and hypertension (HR: 1.83, CI: 1.35-2.46, p= <0.0001). Prevalence of late LVD was 24% (47/197-group 3) and LVMI at 1 year post AVR was predictive of late LVD (HR 1.65, CI 1.11-3.8 per 10 g/ m 2 increment, p= 0.04)). Group 2 had less reverse LV remodeling compared to group 1 at 1 year post AVR (142±39 vs 129±42 g/ m 2 , p=0.02). Conclusions: Risk of LVD was significant even in subset of patients with moderate MAVD. Risk stratification of MAVD should be based on both clinical and echocardiographic parameters. Our data suggest earlier surgical intervention may be required in the MAVD population to prevent postoperative LVD but further studies are needed. Figure legend: FU: follow up

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