scholarly journals Therapeutic angiogenesis by transplantation of autologous bone marrow cells.

2004 ◽  
Vol 48 (4) ◽  
pp. 129-131
Author(s):  
Uichi Ikeda
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Therapeutic Angiogenesis ◽  
Autologous Bone ◽  
Marrow Cells

Autologous bone marrow cell implantation as therapeutic angiogenesis for ischemic hindlimb in diabetic rat model

2003 ◽  
Vol 284 (1) ◽  
pp. H66-H70 ◽  
Author(s):  
Ken Hirata ◽  
Tao-Sheng Li ◽  
Masahiko Nishida ◽  
Hiroshi Ito ◽  
Masunori Matsuzaki ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Marrow Cell ◽  
Autologous Bone Marrow ◽  
Therapeutic Angiogenesis ◽  
Endothelial Differentiation ◽  
Angiogenic Effect ◽  
Autologous Bone ◽  
Cell Implantation ◽  
Marrow Cells

The angiogenic effect induced by autologous bone marrow cell implantation (BMCI) was examined in the ischemic hindlimbs of diabetic and nondiabetic rats. Diabetes mellitus was induced by the systemic administration of streptozotocin. We investigated the production of angiogenic factors and endothelial differentiation from bone marrow cells and the native recovery of blood flow in the ischemic hindlimbs. To observe the angiogenic effect induced by BMCI treatment, 6 × 107 bone marrow cells were injected intramuscularly at six points into the ischemic limbs, and regional perfusion recovery was evaluated with colored microspheres 2 wk later. No difference was found between diabetic and nondiabetic rats in the release of angiogenic factors or endothelial differentiation from bone marrow cells in vitro. The levels of nitric oxide in plasma were significantly lower, and native perfusion recovery in the ischemic hindlimbs was significantly slower in the diabetic rats than in the nondiabetic rats. However, although perfusion recovery was achieved in the ischemic hindlimbs, there was no significant increase in systemic VEGF after BMCI treatment in either the diabetic or nondiabetic rats. Therefore, therapeutic angiogenesis induced by BMCI could be a safe and effective treatment for ischemic limb disease in diabetic patients.

The Prostacyclin Analog Beraprost Sodium Augments the Efficacy of Therapeutic Angiogenesis Induced by Autologous Bone Marrow Cells

2006 ◽  
Vol 20 (5) ◽  
pp. 646-652 ◽  
Author(s):  
Hiroyuki Otsuka ◽  
Hidetoshi Akashi ◽  
Toyoaki Murohara ◽  
Teiji Okazaki ◽  
Satoshi Shintani ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Therapeutic Angiogenesis ◽  
Beraprost Sodium ◽  
Autologous Bone ◽  
Prostacyclin Analog ◽  
Marrow Cells

Safety of Catheter-Based Intramyocardial Autologous Bone Marrow Cells Implantation for Therapeutic Angiogenesis

2006 ◽  
Vol 98 (1) ◽  
pp. 60-62 ◽  
Author(s):  
Hung-Fat Tse ◽  
Sukumaran Thambar ◽  
Yok-Lam Kwong ◽  
Philip Rowlings ◽  
Greg Bellamy ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Therapeutic Angiogenesis ◽  
Autologous Bone ◽  
Marrow Cells

scholarly journals Local Implantation of Autologous Bone Marrow Cells for Therapeutic Angiogenesis in Patients With Ischemic Heart Disease

2001 ◽  
Vol 65 (9) ◽  
pp. 845-847 ◽  
Author(s):  
Kimikazu Hamano ◽  
Masahiko Nishida ◽  
Ken Hirata ◽  
Akihito Mikamo ◽  
Tao-Sheng Li ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Therapeutic Angiogenesis ◽  
Ischemic Heart ◽  
Autologous Bone ◽  
Marrow Cells

Development of cell therapy using autologous bone marrow cells for liver cirrhosis

2005 ◽  
Vol 38 (4) ◽  
pp. 197-202 ◽  
Author(s):  
Isao Sakaida ◽  
Shuji Terai ◽  
Hiroshi Nishina ◽  
Kiwamu Okita
Keyword(s):  
Bone Marrow ◽  
Liver Cirrhosis ◽  
Cell Therapy ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Autologous Bone ◽  
Marrow Cells

The Safety and Feasibility of the Local Implantation of Autologous Bone Marrow Cells for Ischemic Heart Disease

2003 ◽  
Vol 18 ◽  
pp. S69-S75 ◽  
Author(s):  
Tao-Sheng Li ◽  
Kimikazu Hamano ◽  
Ken Hirata ◽  
Toshiro Kobayashi ◽  
Masahiko Nishida
Keyword(s):  
Bone Marrow ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Ischemic Heart ◽  
Autologous Bone ◽  
Marrow Cells

scholarly journals Prevention of corticosteroid-induced osteonecrosis in rabbits by intra-bone marrow injection of autologous bone marrow cells

Rheumatology ◽  
2008 ◽  
Vol 47 (5) ◽  
pp. 591-596 ◽  
Author(s):  
T. Asada ◽  
T. Kushida ◽  
M. Umeda ◽  
K. Oe ◽  
H. Matsuya ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Autologous Bone Marrow ◽  
Autologous Bone ◽  
Marrow Cells
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