Comparison of Stress Perfusion MRI and SPECT for Detection of Myocardial Ischemia in Patients With Angiographically Proven Three-Vessel Coronary Artery Disease

2010 ◽  
Vol 195 (2) ◽  
pp. 356-362 ◽  
Author(s):  
Se-Yeong Chung ◽  
Kang-Young Lee ◽  
Eun Ju Chun ◽  
Won-Woo Lee ◽  
Eun Kyung Park ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Perfusion Mri ◽  
Stress Perfusion ◽  
Vessel Coronary Artery Disease ◽  
Artery Disease ◽  
Vessel Coronary Artery

Is the diagnostic yield of myocardial stress perfusion MRI impaired by three-vessel coronary artery disease?

2015 ◽  
Vol 56 (2) ◽  
pp. 143-151 ◽  
Author(s):  
Bernhard Klumpp ◽  
S Miller ◽  
A Seeger ◽  
AE May ◽  
MP Gawaz ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Diagnostic Yield ◽  
Perfusion Mri ◽  
Stress Perfusion ◽  
Vessel Coronary Artery Disease ◽  
Myocardial Stress ◽  
Artery Disease ◽  
Myocardial Stress Perfusion ◽  
Vessel Coronary Artery

Exercise-induced Silent Myocardial Ischemia in Single Vessel Coronary Artery Disease Associated with Q Wave Infarction

CHEST Journal ◽  
1993 ◽  
Vol 103 (4) ◽  
pp. 1074-1079 ◽  
Author(s):  
Yasuo Matsuda ◽  
Takashi Yamagishi ◽  
Akira Satoh ◽  
Masami Nakatsuka ◽  
Junya Maeda
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Silent Myocardial Ischemia ◽  
Single Vessel ◽  
Vessel Coronary Artery Disease ◽  
Artery Disease ◽  
Exercise Induced ◽  
Vessel Coronary Artery ◽  
Q Wave

Detection of Exercise-Induced Myocardial Ischemia by Multichannel Magnetocardiography in Single Vessel Coronary Artery Disease

2000 ◽  
Vol 5 (2) ◽  
pp. 147-157 ◽  
Author(s):  
Helena Hänninen ◽  
Panu Takala ◽  
Markku Mäkijärvi ◽  
Juha Montonen ◽  
Petri Korhonen ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Single Vessel ◽  
Vessel Coronary Artery Disease ◽  
Artery Disease ◽  
Exercise Induced ◽  
Vessel Coronary Artery

Abstract 4174: Adenosine-Stress CT Myocardial Perfusion Imaging: Comparison with Stress Myocardial Perfusion MRI in Patients with Coronary Artery Disease

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Masaki Ishida ◽  
Hajime Sakuma ◽  
Shingo Kato ◽  
Motonori Nagata ◽  
Nanaka Ishida ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Myocardial Ischemia ◽  
Perfusion Ct ◽  
Perfusion Mri ◽  
Adenosine Stress ◽  
Stress Perfusion ◽  
Stress Myocardial Perfusion ◽  
Artery Disease

Background: CT coronary angiography with vasodilator stress might be of great value in detecting both myocardial ischemia and morphological stenoses of the coronary arteries. Stress myocardial perfusion MRI has been shown to provide accurate assessment of presence and extent of myocardial ischemia in patients with coronary artery disease(CAD). The aim of this study was to determine the value of stress myocardial perfusion CT for the detection of myocardial ischemia by using stress perfusion MRI as a reference method. Methods: The study protocol was approved by the institutional review board and all participants gave written informed consent. Cardiac CT was performed in 12 patients with suspected CAD by using a 64-detector MDCT scanner. Beta-blocker was orally administered prior to CT study. During continuous injection of adenosine, contrast enhanced CT images of the heart were acquired with retrospectively gated helical CT protocol. Adenosine stress myocardial perfusion MRI was performed within 2 weeks from CT perfusion study in all patients. Stress myocardial perfusion MDCT and MR images were qualitatively assessed by two observers using a 16-segment model. Results: All patients completed stress CT study protocol without significant side-effect. Averaged heart rate was 62+/−10 beats/min in the baseline state and 74+/−14 beats/min during adenosine stress. Perfusion abnormality during stress was observed in 83 (43.2%) of 192 segments by MDCT and in 89 (46.4%) of 192 segments by MRI. On a vessel based analysis, stress CT and stress MRI findings are concordant in 30 (83.3%) of 36 territories. The sensitivity, specificity and accuracy of adenosine stress myocardial perfusion CT for the predicting abnormal perfusion on stress perfusion MRI was 84.6%, 80% and 83.3%, respectively. Conclusion: Adenosine stress myocardial perfusion CT can be successfully performed in patients with CAD. Excellent agreement between stress myocardial perfusion CT and MRI observed in this study indicates the value of stress CT approach for comprehensive assessment of morphology and functional significance of CAD.

Relation Between QT Dispersion and the Extent of Myocardial Ischemia in Patients With Three-Vessel Coronary Artery Disease

1998 ◽  
Vol 81 (5) ◽  
pp. 564-568 ◽  
Author(s):  
Ulrich Stierle ◽  
Evangelos Giannitsis ◽  
Abdolhamid Sheikhzadeh ◽  
Dietmar Krüger ◽  
Georg Schmücker ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Qt Dispersion ◽  
Vessel Coronary Artery Disease ◽  
Artery Disease ◽  
Vessel Coronary Artery

Relation between electrocardiographic and scintigraphic location of myocardial ischemia during exercise in one-vessel coronary artery disease

1984 ◽  
Vol 53 (11) ◽  
pp. 1529-1531 ◽  
Author(s):  
Robert M. Fox ◽  
A-Hamid Hakki ◽  
Abdulmassih S. Iskandrian ◽  
Jacqueline Hackney
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Vessel Coronary Artery Disease ◽  
Artery Disease ◽  
Vessel Coronary Artery

scholarly journals Cost-effectiveness analysis of percutaneous coronary intervention for single-vessel coronary artery disease: an economic evaluation of the ORBITA trial

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e044054
Author(s):  
Victoria McCreanor ◽  
Alexandra Nowbar ◽  
Christopher Rajkumar ◽  
Adrian G Barnett ◽  
Darrel Francis ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Cost Effectiveness ◽  
Coronary Artery ◽  
Coronary Intervention ◽  
Single Vessel ◽  
Vessel Coronary Artery Disease ◽  
Effectiveness Analysis ◽  
Percutaneous Coronary ◽  
Artery Disease ◽  
Vessel Coronary Artery

ObjectiveTo evaluate the cost-effectiveness of percutaneous coronary intervention (PCI) compared with placebo in patients with single-vessel coronary artery disease and angina despite anti-anginal therapy.DesignA cost-effectiveness analysis comparing PCI with placebo. A Markov model was used to measure incremental cost-effectiveness, in cost per quality-adjusted life-years (QALYs) gained, over 12 months. Health utility weights were estimated using responses to the EuroQol 5-level questionnaire, from the Objective Randomised Blinded Investigation with optimal medical Therapy of Angioplasty in stable angina trial and UK preference weights. Costs of procedures and follow-up consultations were derived from Healthcare Resource Group reference costs and drug costs from the National Health Service (NHS) drug tariff. Probabilistic sensitivity analysis was undertaken to test the robustness of results to parameter uncertainty. Scenario analyses were performed to test the effect on results of reduced pharmaceutical costs in patients undergoing PCI, and the effect of patients crossing over from placebo to PCI due to refractory angina within 12 months.SettingFive UK NHS hospitals.Participants200 adult patients with stable angina and angiographically severe single-vessel coronary artery disease on anti-anginal therapy.InterventionsAt recruitment, patients received 6 weeks of optimisation of medical therapy for angina after which they were randomised to PCI or a placebo procedure.Outcome measuresIncremental cost-effectiveness ratio (ICER) expressed as cost (in £) per QALY gained for PCI compared with placebo.ResultsThe estimated ICER is £90 218/QALY gained when using PCI compared with placebo in patients receiving medical treatment for angina due to single-vessel coronary artery disease. Results were robust under sensitivity analyses.ConclusionsThe ICER for PCI compared with placebo, in patients with single-vessel coronary artery disease and angina on anti-anginal medication, exceeds the threshold of £30 000 used by the National Institute of Health and Care Excellence when undertaking health technology assessment for the NHS context.Trial registration: The ORBITA study is registered with ClinicalTrials.gov, number NCT02062593.

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