scholarly journals Diuretic 99mTc DTPA renography in assessment of renal function and drainage in infants with antenatally detected hydronephrosis

2015 ◽  
Vol 72 (12) ◽  
pp. 1080-1084
Author(s):  
Marija Radulovic ◽  
Dragan Pucar ◽  
Ljiljana Jaukovic ◽  
Marija Sisic ◽  
Zoran Krstic ◽  
...  

Background/Aim. The controversy over the postnatal management of infants with antenataly detected hydronephrosis (ANH) still exists. We presented the results of diuretic 99mTc diethylenetriamine pentaacetic acid (DTPA) renography in 30 infants with the antenatal diagnosis of unilateral renal pelvic dilatation. The aim of this study was to assess the renal function determined by the pattern of drainage and split renal function (SRF) on diuretic renography and to correlate these findings with anteroposterior pelvic diameter (APD) estimated by ultrasonography. Methods. A total of 30 infants with 60 renal units (RU) (25 boys and 5 girls, median age 6.0 months, range 2-24) presented with unilateral hydronephrosis on ultrasound in the newborn period, underwent DTPA diuretic renal scintigraphy (F+15 protocol). The median APD evaluated on perinatal ultrasound was 15 mm (range 5-30). The postnatal associated clinical diagnosis were pelviureteric junction obstruction (PUJ), simple hydronephrosis, megaureter, vesicoureteral reflux (VUR) and posterior urethral valves in 11, 10, 6, 2 and 1 infant, respectively. Images and Tmax/2 after diuretic stimulation on the background subtracted renographic curves were used as the criteria for classifying the drainage as good, partial, and poor or no drainage. The SRF was calculated with the integral method. Results. Good drainage was shown in 36/60, partial drainage in 13/60 and poor or no drainage in 11/60 RU. The SRF >40% was observed in 55/60 RU, with no RU showing SRF lower than 23.5%. In infants with severe ANH the obstruction was not excluded in 94.1%. Conclusion. Diuretic renography in antenatally detected hydronephrosis should be a useful tool in postnatal follow up, especially in differentiating nonobstructive hydronephrosis from obstructive. It is also importanat to assess and monitor the SRF. Our results suggest that even in the presence of partial or no drainage, SRF may not be significantly impaired.

Author(s):  
Kim Hutton ◽  
Ashok Daya Ram

Most disorders of the urethra in children are congenital in origin and affect boys more commonly than girls. They include; posterior urethral valves (PUV), anterior urethral valves, anterior urethral diverticulum, syringocele, urethral atresia, megalourethra, urethral web, urethral polyp, and urethral duplication. Urethral strictures may be congenital or acquired. Most cases of PUV are now diagnosed prenatally. Postnatal management comprises bladder drainage, correction of any metabolic disturbance, prevention of infection (UTI), and endoscopic valve ablation. Careful follow up is required with the aim of preventing urosepsis and preserving renal function. Persisting bladder dysfunction (‘valve’ bladder) can threaten renal function and should be managed aggressively. Chronic renal failure ultimately affects a third of boys with PUV, of whom 10–20% require renal transplantation during the course of childhood. PUV may also present clinically with recurrent UTI, urinary incontinence, or unexplained lower urinary tract symptoms.


2016 ◽  
Vol 46 (10) ◽  
pp. 1418-1423 ◽  
Author(s):  
Véronique Hochart ◽  
Annie Lahoche ◽  
René-Hilaire Priso ◽  
Véronique Houfflin-Debarge ◽  
Alfred Bassil ◽  
...  

1997 ◽  
Vol 158 (3) ◽  
pp. 1004-1007 ◽  
Author(s):  
Peter M. Cuckow ◽  
M.D. Dinneen ◽  
R.A. Risdon ◽  
P.G. Ransley ◽  
P.G. Duffy

2006 ◽  
Vol 34 (5) ◽  
Author(s):  
Stefanie Kleppe ◽  
Joachim Schmitt ◽  
Annegret Geipel ◽  
Ullrich Gembruch ◽  
Manfred Hansmann ◽  
...  

1996 ◽  
Vol 66 (2) ◽  
pp. 129-130 ◽  
Author(s):  
Jacob W. T. Ng ◽  
Andrew Y. T. Chan ◽  
C. K. Kong ◽  
M. K. Wong

1995 ◽  
pp. 1486-1489 ◽  
Author(s):  
Gordon R. Gluckman ◽  
Laurence S. Baskin ◽  
Guy A. Bogaert ◽  
Robert A. Mevorach ◽  
Robert S. Hattner ◽  
...  

2019 ◽  
Vol 31 (2) ◽  
pp. 68-72
Author(s):  
Shah Md Ahsan Shahid ◽  
Nawshad Ali ◽  
Sayed Sirajul Islam ◽  
Shantona Rani Pal ◽  
Khondokar Seheli Nasrin Lina

Posterior urethral valves (PUV) constitute the most common infra-vesical urinary obstruction in boys. PUV are often accompanied by severe consequences to the lower and upper urinary tract (LUT, UUT). They also represent a major urological cause for pediatric renal transplantations. Surgical options for primary management invariably aim at abolition of valves. However, temporary urinary diversion may sometimes be a viable alternative, especially in critically ill patients or preterm infants. It was a retrospective, descriptive study which was conducted at the Department of Pediatric Surgery, Rajshahi Medical College from January 2018 to December 2018. All stable patients with the diagnosis of posterior urethral valves were included in the study. Endoscopic valve fulguration was performed in all diagnosed patients using bugbee electrode and an adequate sized cystoscope. The procedure was performed under general anesthesia and the urinary bladder was drained with a suitable size Foley's or silicon catheter for 14days. Patients were discharged from the hospital 48-72 hours after the procedure on oral antibiotics and were advised to come to the outpatient department for follow up visits for a period of 6 months. A total of 84 patients were included in the study. All were males with a mean age of 6.5years ranging from 6 months to 12 years. Sixty five patients were without any diversion while 19 had vesicostomy or ureterostomy already done in our department or somewhere else. Stricture urethra was seen in 5 patients, incontinence of urine was seen in 7 patients, nocturnal enuresis in 15 patients and recurrent urinary tract infection in 19 patients. Chronic renal failure was seen in 4 patients while 16 patients lost the follow up.18 patients had an uneventful recovery. Urethral valve ablation is the definitive treatment of posterior urethral valves. Endoscopic urethral valve fulguration is safe, effective and definitive way of management for posterior urethral valves. Early treatment improves the quality of life and prevents the ongoing renal damage. Early presentation in fetal and neonatal life has worst prognosis due to associated renal dysplasia. TAJ 2018; 31(2): 68-72


1993 ◽  
Vol 72 (3) ◽  
pp. 364-369 ◽  
Author(s):  
M. D. DINNEEN ◽  
H. K. DHILLON ◽  
H. C. WARD ◽  
P. G. DUFFY ◽  
P. G. RANSLEY

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