scholarly journals Motor Disorders of the Upper Digestive Tract Review. Clinical Classification of Swallowing Disorders and the Resulting Mechanism of Aspiration.

1995 ◽  
Vol 46 (5) ◽  
pp. 369-374
Author(s):  
Tetsuji Yoshida
Keyword(s):  
Digestive Tract ◽  
Swallowing Disorders ◽  
Motor Disorders ◽  
Clinical Classification ◽  
Upper Digestive Tract

scholarly journals Motor Disorders of the Upper Digestive Tract Review. Conservative Treatments of Dysphagia.

1995 ◽  
Vol 46 (5) ◽  
pp. 380-386 ◽  
Author(s):  
Hiroyuki Ito ◽  
Masao Tomita ◽  
Yousuke Kamide ◽  
Takakuni Kato
Keyword(s):  
Digestive Tract ◽  
Motor Disorders ◽  
Upper Digestive Tract

244 MICROBIOME ANALYSIS OF UPPER DIGESTIVE TRACT BIOPSY SAMPLES FROM INDIVIDUALS ALONG THE METAPLASIA-DYSPLASIA-ADENOCARCINOMA SEQUENCE.

2021 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Jessie Elliott ◽  
Jessie Elliott ◽  
Collette Hand ◽  
Fergus Shanahan ◽  
Thomas Murphy ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Digestive Tract ◽  
Beta Diversity ◽  
Alpha Diversity ◽  
Oesophageal Adenocarcinoma ◽  
Rrna Gene ◽  
Significant Shift ◽  
Clinical Classification ◽  
Upper Digestive Tract ◽  
Normal Oesophagus

Abstract   The human microbiota, the collection of microbes that inhabit the human body, is increasingly being appreciated as playing a role in human health. A seminal example of this relationship is Helicobacter pylori and gastric cancer oncogenesis. The drop in H.pylori infections and non-cardia gastric cancer incidences has coincided with the rise in oesophageal adenocarcinoma (OAC) incidences. We sought to explore the relationship between the upper digestive tract microbiome and OAC oncogenesis. Methods Pinch biopsies were taken from individual’s oesophagus and stomach who were along the metaplasia-dysplasia-adenocarcinoma sequence (GERD, Barrett's oesophagus, dysplasia, OAC, metastatic OAC) as well as healthy controls. We carried out 16 s rRNA gene DNA sequencing protocols on these samples. DNA extraction and library preparation was performed with consideration to the low mass nature of oesophageal biopsies. Raw reads were processed and amplicon sequence variants (ASVs) were generated using the DADA2. We dissected ecological differences between sample site and clinical classification using a variety of approaches including examining differentially abundant taxa and inferred metabolic pathways, alpha diversity and beta-diversity. Results The upper digestive tract was found to be dominated by the genera Streptococcus, Prevotella, and Haemophilus. There was no statistically significant shift in beta diversity with respect to biopsy location. Alpha diversity was reduced in gastric biopsies compare to oesophageal biopsies. A slight yet significant shift was seen in beta diversity (Bray–Curtis Dissimilarity) with respect to clinical classification in biopsies derived from the gastroesophageal junction (GEJ) and stomach. Various taxa were found to be differentially abundant between biopsy site and with regard to clinical classification. Conclusion OAC primarily occurs at the GEJ. Community structure was shifted in samples derived from the GEJ and the stomach. Fusobacterium nucleatum was overrepresented in oesophageal biopsies from individuals with diseased oesophagus compared to individuals with a histologically normal oesophagus. This bacterium has been implicated in oncogenesis of various cancers most notably colorectal cancer. Serval ASVs assigned to the genus Prevotella were depleted in stomachs of individuals with metastatic OAC compared to all other groups.

The acute and long-term prognosis of cerebral infarction on the basis of the clinical classification of the Oxfordshire community stroke project

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S151-S151
Author(s):  
Katsunori Isa ◽  
Takashi Tokashiki ◽  
Koichiro Okumura ◽  
Kunitoshi Iseki ◽  
Shuichi Takishita
Keyword(s):  
Cerebral Infarction ◽  
Clinical Classification ◽  
Oxfordshire Community Stroke Project ◽  
Long Term Prognosis

Clinical Classification of Patellofemoral Pain and Dysfunction

1998 ◽  
Vol 28 (5) ◽  
pp. 299-306 ◽  
Author(s):  
S. Wendell Holmes ◽  
William G. Clancy
Keyword(s):  
Patellofemoral Pain ◽  
Clinical Classification

Clinical classification of hyperuricemia in patients with chronic kidney disease

2021 ◽  
Author(s):  
Fengqin Li ◽  
Hui Guo ◽  
Jianan Zou ◽  
Chensheng Fu ◽  
Song Liu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Clinical Classification

scholarly journals 310 A new proposal for the clinical classification of vulvar lichen sclerosus: an observational prospective study

2020 ◽  
Author(s):  
Veronica Boero ◽  
Carlo A Liverani ◽  
Massimiliano Brambilla ◽  
Ermelinda Monti ◽  
Filippo Murina ◽  
...  
Keyword(s):  
Prospective Study ◽  
Lichen Sclerosus ◽  
Clinical Classification ◽  
Observational Prospective Study ◽  
Vulvar Lichen Sclerosus
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