Metabolic disturbances of second generation antipsychotics in stable long term outpatients: a two years follow up study

Author(s):  
Diego Mendez
2014 ◽  
Vol 215 (1) ◽  
pp. 20-25 ◽  
Author(s):  
Hong-Xia Zhang ◽  
Xiao-Ling Shen ◽  
Hui Zhou ◽  
Xiao-Min Yang ◽  
Hui-Fang Wang ◽  
...  

2020 ◽  
Vol 23 (8) ◽  
pp. 491-495
Author(s):  
Karolina Skonieczna-Żydecka ◽  
Igor Łoniewski ◽  
Ewa Stachowska ◽  
Wojciech Marlicz ◽  
Christoph U Correll

Abstract Second-generation antipsychotic–related weight gain and metabolic disturbances are a major public health issue given the widespread prescribing of these medications. The lack of clearly known mechanisms of cardiometabolic adverse effects and the relevance of cardiometabolic health for survival make this an important area for research. While nonpharmacologic and some pharmacologic treatments have shown benefits vs control conditions or placebo, the effects are modest and long-term benefits are less clear. Therefore, new approaches to mitigate second-generation antipsychotic–associated cardiometabolic burden are sorely needed.


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