scholarly journals Circulating Tumor Cells (CTCs) with small-cell like pathology are prevalent in metastatic Castration Resistant Prostate Cancer (mCRPC) and show selective pharmacodynamic reductions in patients treated with platinum but not ARSi or taxane.

2020 ◽  
Author(s):  
Joseph Schonhoft
Keyword(s):  
Prostate Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Small Cell ◽  
Castration Resistant Prostate Cancer ◽  
Castration Resistant

Dramatically Elevated Circulating Tumor Cell Numbers in a Patient With Small Cell Neuroendocrine Carcinoma of the Prostate

2010 ◽  
Vol 134 (1) ◽  
pp. 120-123
Author(s):  
Fanny Chan ◽  
Oscar Goodman ◽  
Louis Fink ◽  
Nicholas J. Vogelzang ◽  
David Pomerantz ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Specific Antigen ◽  
Metastatic Breast ◽  
Circulating Tumor Cell ◽  
Small Cell ◽  
Castration Resistant Prostate Cancer ◽  
Normal Prostate ◽  
Castration Resistant

Abstract Detection of circulating tumor cells in whole blood is a useful prognostic tool for patients with castration-resistant prostate cancer, as well as for patients with metastatic breast cancer and colorectal carcinoma. In this report, we present the case of a patient with neuroendocrine small cell prostate cancer with normal prostate-specific antigen levels throughout the course of disease but who had markedly elevated circulating tumor cells, as detected with the CellSearch (Veridex) system.

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