Downy Mildew, Plasmopara viticola, causes major damage and economic loss to many wine grape cultivars grown in the Northeast. The purpose of the experiment was to test the efficacy of Vossen Blue (VB; iron pigment) in association with fungicides for the control of Downy Mildew disease of wine grapes in New Jersey. The experimental plot was a planting of `Seyval Blanc' (5th leaf). Treatments (applied via back-pack sprayer) included no fungicide (control I), full fungicide (FF) (RCE commercial recs; control II), FF + 4%VB, FF + 8%VB, 8%VB, Half Rate Fungicide (HF) + 4%VB, HF + 8%VB. There were no significant differences between treatments for total yield, average cluster weight, average berry weight, Brix %, and pH. Spectrophotometric (Hunter's Lab) analysis of foliage samples revealed that leaf samples from the VB treatments had greater green color (correlate: increased chlorophyll). Analysis of subjective (1-9) disease incidence data: FF8 significantly lower disease score that FF; FF4, HF4, HF8, and FF no difference. Compared to normal full fungicide: superior Downy Mildew control was achieved by adding VB to full fungicide; equal control was achieved with half fungicide and VB.