Minimax Design vs. Simon’s Optimal Design for Single-Arm Two-Stage Phase II Cancer Clinical Trials

Biomedical Journal of Scientific & Technical Research ◽

10.26717/bjstr.2021.37.006024 ◽

2021 ◽

Vol 37 (4) ◽

Author(s):

Sin-Ho Jung

Keyword(s):

Clinical Trials ◽

Optimal Design ◽

Phase Ii ◽

Cancer Clinical Trials ◽

Two Stage ◽

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Optimal Two-Stage Design for the Phase II Cancer Clinical Trials With Responses and Early Progression as Co-primary Endpoints

Statistics in Biopharmaceutical Research ◽

10.1198/sbr.2009.08079 ◽

2010 ◽

Vol 2 (3) ◽

pp. 348-354

Author(s):

Xianming Tan ◽

Glen Takahara ◽

Dongsheng Tu

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Cancer Clinical Trials ◽

Two Stage ◽

Stage Design ◽

Primary Endpoints ◽

Early Progression ◽

Two Stage Design

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Admissible two-stage designs for phase II cancer clinical trials

Statistics in Medicine ◽

10.1002/sim.1600 ◽

2004 ◽

Vol 23 (4) ◽

pp. 561-569 ◽

Author(s):

Sin-Ho Jung ◽

Taiyeong Lee ◽

KyungMann Kim ◽

Stephen L. George

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Cancer Clinical Trials ◽

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Two-stage designs optimal under the alternative hypothesis for phase II cancer clinical trials

Contemporary Clinical Trials ◽

10.1016/j.cct.2010.07.008 ◽

2010 ◽

Vol 31 (6) ◽

pp. 572-578 ◽

Author(s):

A.P. Mander ◽

S.G. Thompson

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Alternative Hypothesis ◽

Cancer Clinical Trials ◽

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Modified Simon’s minimax and optimal two-stage designs for single-arm phase II cancer clinical trials

10.18632/oncotarget.26981 ◽

2019 ◽

Vol 10 (42) ◽

pp. 4255-4261 ◽

Author(s):

Jongphil Kim ◽

Michael J. Schell

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Cancer Clinical Trials ◽

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Two-Stage Design: Phase II Cancer Clinical Trials

Encyclopedia of Biopharmaceutical Statistics ◽

10.3109/9781439822463.224 ◽

2010 ◽

pp. 1397-1400

Author(s):

Sin-Ho Jung

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Cancer Clinical Trials ◽

Design Phase ◽

Two Stage ◽

Stage Design ◽

Two Stage Design

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Sample size determination for the two-stage design of a phase II cancer clinical trials with correlated unbalance binary endpoints

Controlled Clinical Trials ◽

10.1016/s0197-2456(98)80121-9 ◽

1998 ◽

Vol 19 (3) ◽

pp. S40

Author(s):

Yu Shyr ◽

Brenda P. Nicholson ◽

David H. Johnson

Keyword(s):

Clinical Trials ◽

Sample Size ◽

Phase Ii ◽

Sample Size Determination ◽

Cancer Clinical Trials ◽

Size Determination ◽

Two Stage ◽

Stage Design ◽

Two Stage Design

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Admissible two-stage designs for phase II cancer clinical trials that incorporate the expected sample size under the alternative hypothesis

Pharmaceutical Statistics ◽

10.1002/pst.501 ◽

2012 ◽

Vol 11 (2) ◽

pp. 91-96 ◽

Author(s):

Adrian P. Mander ◽

James M.S. Wason ◽

Michael J. Sweeting ◽

Simon G. Thompson

Keyword(s):

Clinical Trials ◽

Sample Size ◽

Phase Ii ◽

Alternative Hypothesis ◽

Cancer Clinical Trials ◽

Two Stage ◽

Expected Sample Size

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Improved two-stage tests for stratified phase II cancer clinical trials

Statistics in Medicine ◽

10.1002/sim.5314 ◽

2012 ◽

Vol 31 (16) ◽

pp. 1688-1698 ◽

Author(s):

Myron N. Chang ◽

Jonathan J. Shuster ◽

Wei Hou

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Cancer Clinical Trials ◽

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A new adaptive design based on Simon's two-stage optimal design for phase II clinical trials

Contemporary Clinical Trials ◽

10.1016/j.cct.2012.07.003 ◽

2012 ◽

Vol 33 (6) ◽

pp. 1255-1260 ◽

Author(s):

Hua Jin ◽

Zhen Wei

Keyword(s):

Clinical Trials ◽

Optimal Design ◽

Phase Ii ◽

Adaptive Design ◽

Two Stage ◽

Phase Ii Clinical Trials

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A Design Alternative for Two-Stage, Phase II, Multicenter Cancer Clinical Trials

Controlled Clinical Trials ◽

10.1016/s0197-2456(98)00012-9 ◽

1998 ◽

Vol 19 (5) ◽

pp. 440-450 ◽

Author(s):

James E.Herndon II

Keyword(s):

Clinical Trials ◽

Phase Ii ◽

Cancer Clinical Trials ◽

Two Stage ◽

Design Alternative

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