Multiple primary neoplasms of the female genital tract: diffuse Mullerian neoplasia

1982 ◽  
Vol 2 (3) ◽  
pp. 175-176 ◽  
Author(s):  
C. H. Buckley ◽  
H. Fox ◽  
P. Donnai
1982 ◽  
Vol 13 (2) ◽  
pp. 271-277 ◽  
Author(s):  
David L. Matlock ◽  
Frank A. Salem ◽  
Elsworth H. Charles ◽  
Edward W. Savage

1980 ◽  
Vol 9 (1) ◽  
pp. 120-124 ◽  
Author(s):  
Charles T. Milano ◽  
Gunter Deppe ◽  
Liane Deligdisch ◽  
Carmel J. Cohen

Open Medicine ◽  
2006 ◽  
Vol 1 (1) ◽  
pp. 87-98
Author(s):  
Cornelia Amalinei ◽  
Raluca Balan ◽  
Luminita Ivan ◽  
Razvan Socolov ◽  
Demetra Socolov ◽  
...  

AbstractThe synchronous occurence of primary carcinomas of endometrium and ovary is well recognized. Malignant peripheral nerve sheath tumours (MPNSTs) may also rarely occur in patients diagnosed with malignancies of the female genital tract. We report a rare case of synchronous primary carcinomas of endometrium and ovary, followed by a metachronous retroperitoneal MPNST. Ascites cytology and endometrial biopsy, followed by hysterectomy and bilateral adnexectomy, were performed to remove the synchronous tumors. Histology was suggestive of synchronous endometrial endometrioid carcinoma and ovarian mucinous adenocarcinoma. After the removal of the retroperitoneal tumor, a MPNST was diagnosed by immunohistochemistry. The patient developed two consecutive vaginal tumors diagnosed as metastases of the previously diagnosed endometrial carcinoma. Although synchronous tumors of endometrium and ovary were relatively early staged and consequently had a favorable prognosis, subsequently occuring implants along the lower genital tract and the metachronous MPNST added up to a poor prognosis.


2016 ◽  
Author(s):  
Vani Malhotra ◽  
Smiti Nanda ◽  
Meenakshi Chauhan ◽  
Vandana Bhuria

Background: Synchronous primary malignancies of the female genital tract constitute 1.7% of all genital malignancies. Case: A 45-year-old para 5 woman presented with loss of appetite and abdominal distention. Provisional diagnosis of ovarian malignancy was made. Final histopathology of the specimen revealed ovarian papillary serous cystadenocacinoma with cervical leiomyosarcoma. She received chemotherapy. Results: Patient is on regular follow-up. Conclusion: The coexistence of primary neoplasms in the ovary and cervix are rare. A normal appearing organ may have a hidden malignancy. So, every surgical specimen should be subjected to detailed histopathological examination. Also, the possibility of synchronous malignancy elsewhere in body should be kept in mind while working on a genital malignancy.


Sign in / Sign up

Export Citation Format

Share Document