The Natural History of Thoracic Aortic Aneurysms: Etiology, Pathogenesis, and Evidence-Based Decision Making for Surgical Intervention

2007 ◽  
pp. 209-240
Keyword(s):  
Decision Making ◽  
Natural History ◽  
Surgical Intervention ◽  
Aortic Aneurysms ◽  
Evidence Based ◽  
Thoracic Aortic Aneurysms ◽  
History Of ◽  
Evidence Based Decision Making

scholarly journals The Genetics of Thoracic Aortic Aneurysms and Dissection: A Clinical Perspective

Biomolecules ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 182 ◽  
Author(s):  
Nicolai P. Ostberg ◽  
Mohammad A. Zafar ◽  
Bulat A. Ziganshin ◽  
John A. Elefteriades
Keyword(s):  
Genetic Basis ◽  
Surgical Intervention ◽  
Clinical Manifestations ◽  
Aortic Aneurysms ◽  
Screening Tests ◽  
Cellular Mechanisms ◽  
Biomechanical Stress ◽  
Thoracic Aortic Aneurysms ◽  
Aortic Aneurysm And Dissection ◽  
History Of

Thoracic aortic aneurysm and dissection (TAAD) affects many patients globally and has high mortality rates if undetected. Once thought to be solely a degenerative disease that afflicted the aorta due to high pressure and biomechanical stress, extensive investigation of the heritability and natural history of TAAD has shown a clear genetic basis for the disease. Here, we review both the cellular mechanisms and clinical manifestations of syndromic and non-syndromic TAAD. We particularly focus on genes that have been linked to dissection at diameters <5.0 cm, the current lower bound for surgical intervention. Genetic screening tests to identify patients with TAAD associated mutations that place them at high risk for dissection are also discussed.

scholarly journals Natural history of thoracic aortic aneurysms

2012 ◽  
Vol 56 (2) ◽  
pp. 565-571 ◽  
Author(s):  
Gregory A. Kuzmik ◽  
Adam X. Sang ◽  
John A. Elefteriades
Keyword(s):  
Natural History ◽  
Aortic Aneurysms ◽  
Thoracic Aortic Aneurysms ◽  
History Of

Prospective Study of the Natural History of Thoracic Aortic Aneurysms

1997 ◽  
Vol 63 (6) ◽  
pp. 1533-1545 ◽  
Author(s):  
Tatu Juvonen ◽  
M.Arisan Ergin ◽  
Jan D Galla ◽  
Steven L Lansman ◽  
Khanh H Nguyen ◽  
...  
Keyword(s):  
Natural History ◽  
Prospective Study ◽  
Aortic Aneurysms ◽  
Thoracic Aortic Aneurysms ◽  
History Of

Natural History of Arteriosclerotic Thoracic Aortic Aneurysms

1978 ◽  
Vol 26 (5) ◽  
pp. 468-473 ◽  
Author(s):  
J. Judson McNamara ◽  
Virginia M. Pressler
Keyword(s):  
Natural History ◽  
Aortic Aneurysms ◽  
Thoracic Aortic Aneurysms ◽  
History Of

scholarly journals The natural history of thoracic aortic aneurysms

1994 ◽  
Vol 107 (5) ◽  
pp. 1323-1333 ◽  
Author(s):  
Otto E. Dapunt ◽  
Jan D. Galla ◽  
Ali M. Sadeghi ◽  
Steven L. Lansman ◽  
Craig K. Mezrow ◽  
...  
Keyword(s):  
Natural History ◽  
Aortic Aneurysms ◽  
Thoracic Aortic Aneurysms ◽  
History Of

A Population-Based Study of the Incidence and Natural History of Degenerative Thoracic Aortic Aneurysms

2021 ◽  
Author(s):  
Ying Huang ◽  
Hartzell V. Schaff ◽  
Joseph A. Dearani ◽  
Gustavo S. Oderich ◽  
Thomas C. Bower ◽  
...  
Keyword(s):  
Natural History ◽  
Population Based ◽  
Aortic Aneurysms ◽  
Population Based Study ◽  
Thoracic Aortic Aneurysms ◽  
History Of
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