scholarly journals Familial Chylomicronemia Syndrome Presenting With Acute Necrotizing Pancreatitis in a Five Month Infant

2010 ◽  
Vol 30 (2) ◽  
pp. 110-112 ◽  
Author(s):  
Amirmasoud Borghei ◽  
Mahba Azizi

Familial chylomicronemia syndrome (FCS) is a rare disease characterized by severe fastinghypertriglyceridemia and chylomicronemia, which is inherited in an autosomal recessive manner. It isarisen from apolipoprotein C-ll deficiency or Lipoprotein Lipase(LPL) Deficiency.We report a 5-month-oldmale infant FCS presenting with acute abdominal pain and post surgical diagnosis of acute necrotizingpancreatitis.Key words: Pancreatitis; chylomicronemia; hyperlipidemia; lipoprotein lipase.DOI: 10.3126/jnps.v30i2.2431J. Nepal Paediatr. Soc. May-August, 2010 Vol 30(2) 110-112

2022 ◽  
Vol 6 (1) ◽  
pp. 01-03
Author(s):  
Nanda Rachmad Putra Gofur ◽  
Aisyah Rachmadani Putri Gofur ◽  
Soesilaningtyas Soesilaningtyas ◽  
Rizki Nur Rachman Putra Gofur ◽  
Mega Kahdina ◽  
...  

Introduction: Acute pancreatitis is an inflammatory disease of the pancreas with clinical manifestations that vary from mild to severe manifestations to death. The incidence of pancreatitis varies in various countries in the world and depends on the cause such as alcohol, gallstones, and metabolic factors. The clinical picture and the main symptom in patients with acute pancreatitis is abdominal pain. Abdominal pain varies from mild to severe and excruciating. Abdominal pain that is felt is constant and dull, and is usually felt in the epigastrium and periumbilicus and often spreads to the back, chest, waist, and lower abdomen. Discussion: The onset of acute pancreatitis, the patient should be evaluated for hemodynamic status immediately and receive the necessary resuscitation measures. Patients with acute pancreatitis should receive aggressive intravenous rehydration (250 - 500 ml/hour with isotonic crystalloid fluid) as early as possible with close monitoring, unless contraindicated with cardiovascular and/or renal comorbidities. It is most effective within the first 12-24 hours, but after that the benefits may diminish. Debridement (necrosectomy) is the gold standard in infected acute necrotizing pancreatitis and peripancreatic necrosis. Indications for intervention either through radiological, endoscopic or surgical procedures in necrotizing pancreatitis are suspected or proven infected necrotizing pancreatitis with clinical deterioration, especially after the necrotic tissue has been encapsulated with thick walls (walled-off necrosis). Sterile necrotizing pancreatitis with persistent organ failure several weeks after the onset of acute pancreatitis, particularly after the necrotic tissue has been encapsulated with thick walls (walled-off necrosis). Conclusion: Surgical management is often used in pancreatitis associated with gallstones. Cholecystectomy within 48 hours of the complaint can increase healing time. In addition, cholecystectomy performed early may not increase the risk of complications secondary to surgery. Surgery is not performed in acute necrotizing pancreatitis until the inflammation is reduced and the fluid accumulation no longer increases in size.


2017 ◽  
Vol 25 (5) ◽  
pp. 253-257
Author(s):  
Joana C. Branco ◽  
Mariana F. Cardoso ◽  
Luís Carvalho Lourenço ◽  
Liliana Santos ◽  
David Valadas Horta ◽  
...  

Author(s):  
Yash Kripalani ◽  
Koulsoum Houssein ◽  
Anjum Shaikh

SARS-CoV-2 causes severe acute respiratory distress and other clinical complications such as thromboembolic events and gastrointestinal tract disorders, which generally present with abdominal pain. In the case report, we describe a patient who had severe viral necrotizing pancreatitis associated with COVID-19 infection.


2008 ◽  
Vol 46 (05) ◽  
Author(s):  
G Biczó ◽  
P Hegyi ◽  
S Dósa ◽  
B Iványi ◽  
K Jármay ◽  
...  

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