We presented results in major scientific areas being developed in the North-West Public Health Research center
throughout the 95-year history of its existence. Leningrad Institute for the Study of Occupational Diseases, which
was established in 1924, have developed scientific bases for diagnosis, treatment, and prevention of occupational
diseases; created national school of industrial toxicology, developed procedure for hygienic regulation of harmful
occupational and environmental factors in human environment. The stages of activity in the field of occupational
pathology, occupational hygiene, industrial toxicology are reviewed. Currently, the research is underway to assess
occupational and environmental risks to public health from exposure to harmful factors, and to improve measures
to minimize them. Priorities for further development of scientific research are identified.