scholarly journals Peripheral transcriptomic biomarkers for early detection of sporadic Alzheimer disease?

2018 ◽  
Vol 20 (4) ◽  
pp. 293-300 ◽  
Author(s):  
Adva Hadar ◽  
◽  
David Gurwitz ◽  
Author(s):  
Mark Hallett

Apraxia is the inability to perform skilled and/or learned movements, not explainable on the basis of more elemental abnormalities. There are several types of apraxia of which the most commonly recognized are (1) limb kinetic apraxia, the loss of hand and finger dexterity; (2) ideomotor apraxia, deficits in pantomiming tool use and gestures with temporal and spatial errors, but with knowledge of the tasks still present; (3) ideational apraxia, the failure to carry out a series of tasks using multiple objects for an intended purpose; and (4) conceptual apraxia, loss of tool knowledge, when tools and objects are used inappropriately. Apraxia can be a feature of both frontotemporal dementia and Alzheimer disease, and even a rare presenting manifestation of both. How sensitive apraxia measures would be in early detection is not well known.


Neurology ◽  
2011 ◽  
Vol 77 (5) ◽  
pp. 453-460 ◽  
Author(s):  
N. M. Scheinin ◽  
S. Aalto ◽  
J. Kaprio ◽  
M. Koskenvuo ◽  
I. Raiha ◽  
...  

2020 ◽  
Vol 176 ◽  
pp. 763-770
Author(s):  
Randa Ben Ammar ◽  
Yassine Ben Ayed

2004 ◽  
Vol 369 (3) ◽  
pp. 219-223 ◽  
Author(s):  
Claudia Günther ◽  
Kirsten von Hadeln ◽  
Tomas Müller-Thomsen ◽  
Antonella Alberici ◽  
Giuliano Binetti ◽  
...  

2008 ◽  
Vol 119 (9) ◽  
pp. e123
Author(s):  
A. Fernández Nin ◽  
Y. Fernández ◽  
M.A. Bobes León ◽  
F. Lopera ◽  
Y.T. Quiroz ◽  
...  

1996 ◽  
Vol 67 (4) ◽  
pp. 429-429 ◽  
Author(s):  
Susumu Higuchi ◽  
Sachio Matsushita ◽  
Yoshio Hasegawa ◽  
Taro Muramatsu ◽  
Shigeru Itabashi ◽  
...  

2004 ◽  
Vol 35 (3) ◽  
pp. 232-245 ◽  
Author(s):  
Barbara Borroni ◽  
Monica DiLuca ◽  
Flaminio Cattabeni ◽  
Alessandro Padovani

2015 ◽  
Vol 129 (5) ◽  
pp. 757-762 ◽  
Author(s):  
Kurt A. Jellinger ◽  
Irina Alafuzoff ◽  
Johannes Attems ◽  
Thomas G. Beach ◽  
Nigel J. Cairns ◽  
...  

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