scholarly journals Striatonigral Degeneration

2019 ◽  
Author(s):  
Keyword(s):  
Striatonigral Degeneration

MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration

2004 ◽  
Vol 185 (1) ◽  
pp. 47-62 ◽  
Author(s):  
P.O. Fernagut ◽  
E. Diguet ◽  
B. Bioulac ◽  
F. Tison
Keyword(s):  
Striatonigral Degeneration ◽  
Nitropropionic Acid ◽  
3 Nitropropionic Acid

Effects of riluzole on combined MPTP?+?3-nitropropionic acid-induced mild to moderate striatonigral degeneration in mice

2004 ◽  
Vol 112 (5) ◽  
pp. 613-631 ◽  
Author(s):  
E. Diguet ◽  
P.-O. Fernagut ◽  
C. Scherfler ◽  
G. Wenning ◽  
F. Tison
Keyword(s):  
Striatonigral Degeneration ◽  
Nitropropionic Acid ◽  
3 Nitropropionic Acid

Striatonigral degeneration response to levodopa therapy

1972 ◽  
Vol 16 (3) ◽  
pp. 331-341 ◽  
Author(s):  
A.H. Rajput ◽  
K.H. Kazi ◽  
B. Rozdilsky
Keyword(s):  
Levodopa Therapy ◽  
Striatonigral Degeneration

Shy-Drager Syndrome. Neuropathological Correlation and Response to Levodopa Therapy

1976 ◽  
Vol 3 (3) ◽  
pp. 167-173 ◽  
Author(s):  
Jacques De Lean ◽  
John H.N. Deck
Keyword(s):  
Lewy Bodies ◽  
Sympathetic Ganglia ◽  
Levodopa Therapy ◽  
Striatonigral Degeneration ◽  
Preganglionic Neurons ◽  
Progressive Loss ◽  
System Degeneration ◽  
Nigral Degeneration ◽  
Depressor Action ◽  
Lateral Sclerosis

SUMMARY:The post-mortem examination of the nervous system of a patient with Shy-Drager syndrome successfully treated with levodopa (Sharpe et al, 1972) revealed features of striato-nigral degeneration and amyotrophic lateral sclerosis, a cerebellar system degeneration and a loss of approximately 75% of sympathetic preganglionic neurons. Lewy bodies were not present and no detectable changes were observed in the sympathetic prevertebral ganglia.While the limited and transient beneficial effect of levodopa on the bradykinesia in our case is possibly due to the progressive loss of striatal dopaminergic receptors seen in striatonigral degeneration, we propose that in Shy-Drager syndrome, levodopa therapy benefits orthostatic hypotension because of a suppression of the central depressor action of this drug. This suppression is attributable to functional disconnection of sympathetic ganglia secondary to the loss of preganglionic neurons or to degeneration of central autonomic catechoiaminergic systems.

A novel grading scale for striatonigral degeneration (multiple system atrophy)

2002 ◽  
Vol 109 (3) ◽  
pp. 307-320 ◽  
Author(s):  
G. K. Wenning ◽  
K. Seppi ◽  
F. Tison ◽  
K. Jellinger
Keyword(s):  
Multiple System Atrophy ◽  
Striatonigral Degeneration ◽  
Grading Scale

Failure of neuronal protection by inhibition of glial activation in a rat model of striatonigral degeneration

2004 ◽  
Vol 78 (1) ◽  
pp. 87-91 ◽  
Author(s):  
Nadia Stefanova ◽  
Monika Mitschnigg ◽  
Imad Ghorayeb ◽  
Elsa Diguet ◽  
Felix Geser ◽  
...  
Keyword(s):  
Rat Model ◽  
Glial Activation ◽  
Striatonigral Degeneration ◽  
Neuronal Protection

Subregional loss of putaminal efferents to the basal ganglia output nuclei may cause parkinsonism in striatonigral degeneration

Neurology ◽  
1996 ◽  
Vol 47 (4) ◽  
pp. 1032-1036 ◽  
Author(s):  
S. Goto ◽  
S. Matsumoto ◽  
Y. Ushio ◽  
A. Hirano
Keyword(s):  
Basal Ganglia ◽  
Striatonigral Degeneration

scholarly journals Novel VAC14 variants identified in two Chinese siblings with childhood‐onset striatonigral degeneration

2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Shuang Liao ◽  
Tingting Chen ◽  
Ying Dai ◽  
Yanqin Wang ◽  
Fangrui Wu ◽  
...  
Keyword(s):  
Childhood Onset ◽  
Striatonigral Degeneration
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