scholarly journals Malignant Intestinal Neoplasm

2020 ◽  
Author(s):  
Keyword(s):  
Digestion ◽  
1953 ◽  
Vol 79 (6) ◽  
pp. 343-345 ◽  
Author(s):  
P. Rechnitzer

1995 ◽  
Vol 9 (5) ◽  
pp. 242-246 ◽  
Author(s):  
Hugh J Freeman

Previous reports have suggested that autoimmune thyroid disorders (including Hashimoto’s or lymphocytic thyroiditis) may occur in patients with celiac disease. In this study, the prevalence of thyroid disease was explored in a series of 96 consecutive patients seen with biopsy-defined adult celiac disease (average age 47.3 years). Sixteen celiac patients (average age 58.1 years) were detected with hypothyroidism, including four treated with radio-iodine ablation or thyroidectomy for Grave’s disease. In addition to celiac disease, almost half had dermatitis herpetiformis, a small intestinal neoplasm (particularly lymphoma) or both. Diagnosis of thyroid disease preceded diagnosis of celiac disease in 13 patients or was made concurrently in two patients. In only one patient was thyroid disease detected after celiac disease was diagnosed. This indicates that thyroid diseases occur more commonly in celiac disease than is currently appreciated, possibly due to shared embryological origins or common immunopathological features, and may be the presenting clinical manifestation in adults especially if there is coexistent dermatitis herpetiformis. Careful monitoring of this subgroup may be warranted because of the frequency of neoplastic intestinal diseases, particularly lymphoma.


Author(s):  
Mónica Saavedra Cruz ◽  
Luis Núñez Ochoa ◽  
Hortensia Corona-Monjaras

Descripción del caso: perro de nueve años de edad, macho, mestizo (Terranova/chow chow) con historia de diarrea crónica, vómito y sin respuesta a diferentes tratamientos; fue recibido en el Hospital Veterinario de Especialidades de la Universidad Nacional Autónoma de México para continuar con el proceso diagnóstico de una probable neoplasia intestinal.Hallazgos clínicos: condición corporal 2/5, 6 % de deshidratación, depresión, vómito, diarrea, dolor abdominal y anorexia. El diagnóstico fue pancreatitis aguda y un proceso infiltrativo (neoplásico o inflamatorio). En los estudios sanguíneos se observó anemia ligera a moderada relacionada con inflamación crónica y posible pérdida entérica; hipoproteinemia por pérdidas entéricas (diarrea) y anorexia prolongada, y en el leucograma hubo inflamación activa de forma persistente.Pruebas de laboratorio: ultrasonido que mostró cambios en el páncreas y el duodeno. Se realizaron varios estudios sanguíneos y una gasometría arterial, las alteraciones fueron asociadas a dolor.Tratamiento y evolución: el paciente fue hospitalizado para realizar biopsia quirúrgica y colocarle una sonda de yeyunostomía; tres días después mostró dolor, melena, empeoramiento del estado mental y efusión abdominal. El perro fue diagnosticado con peritonitis séptica. Debido a la condición y riesgo del paciente, se le practicó la eutanasia.Relevancia clínica: las neoplasias intestinales en perros son raras, el adenocarcinoma es el segundo más común. Como factores de pobre pronóstico se mencionan, la localización, el tamaño y la pobre diferenciación histológica. Este reporte es relevante por la limitada información e incidencia de este tipo de neoplasia, principalmente por la localización y manejo médico y quirúrgico. Duodenal adenocarcinoma in a dog: diagnostic approach and complications Abstract Case description: nine-year-old male dog, mix breed (Terranova/chow chow) with a history of chronic diarrhea and vomiting without response to different treatments. It continues in diagnosis process due to probable intestinal neoplasia.Clinical findings: body condition 2/5, 6 % dehydration, depression, vomiting, diarrhea, abdominal pain and anorexia. The diagnosis was acute pancreatitis and infiltrative intestinal process (neoplastic or inflammatory). The blood counts observed mild to moderate anemia related to chronic inflammation and possible enteric losses, hypoproteinemia due to enteric losses (diarrhea) and prolonged anorexia, and in the leukogram it had active inflammation persistently.Lab test: ultrasound showed changes in the pancreas and duodenum. Several blood counts were performed, and an arterial blood gas, the alterations were associated with pain.Treatment and evolution: the patient was hospitalized for surgical biopsy and placement of a jejunostomy tube; three days later there was pain, mane, worsening mental state and abdominal effusion. The dog was diagnosed with septic peritonitis was. Due to the patient´s risk, euthanasia was practiced.Clinical relevance: intestinal neoplasm in dogs are rare, the adenocarcinoma is the second most common. As factors of poor prognosis, the location, size and poor histological differentiation are mentioned. It is important to know the available tools to make a proper diagnosis, establish the prognosis and take therapeutic decisions. The relevance of this case report is the limited information and incidence of this type of neoplasm, mainly the location, which implies a medical-surgical management different from others tumours.Key words: duodenal adenocarcinoma, effusion citology, lactate, glucose, intestinal neoplasia.


1974 ◽  
Vol 11 (4) ◽  
pp. 340-349 ◽  
Author(s):  
R. C. Giles ◽  
P. K. Hildebrandt ◽  
C. A. Montgomery

An intestinal neoplasm with morphologic and histochemical characteristics of a carcinoid tumor caused clinical disease and death in a 9-year-old male Old English Sheepdog. Clinical findings over a 9-month period included intermittent diarrhea, intestinal bleeding, emaciation, anemia, and thrombocytopenia. The tumor was in the intestinal wall at the ileocecal junction and had metastasized to the liver. It was composed of densely populated nests and cords of round to polyhedral cells that were argentaffinic and argyrophilic. It was similar to ileocecal carcinoid tumors of man.


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