Benign Splenic Neoplasm

2020 ◽  
Author(s):  
Keyword(s):  
2018 ◽  
pp. 626-638
Author(s):  
Ernesto Santos ◽  
Joshua Pinter ◽  
Kevin McCluskey

The reticuloendothelial system is the portion of the immune system consisting of phagocytic cells found in reticular connective tissue in the spleen, liver, lungs, bone marrow, and lymph nodes. For the purposes of this chapter, the discussion will be limited to interventions within the spleen and the lymphatic system. Splenic arterial interventions are performed to treat a variety of clinical conditions, including abdominal trauma, hypersplenism, splenic arterial aneurysm/pseudoaneurysm, portal hypertension, and splenic neoplasm, and they provide an alternative to open surgery. Although not commonly performed, percutaneous splenic biopsy and drainage are relatively safe and efficacious procedures. Lymphangiography is a therapeutic option for patients with chylothorax, chylous ascites, and lymphatic fistula. Percutaneous thoracic duct embolization (TDE) is an alternative to surgical ligation of the thoracic duct (TD).


2016 ◽  
Vol 82 (8) ◽  
pp. 204-205
Author(s):  
Charles Fredericks ◽  
John Kubasiak ◽  
Vishal Kumar ◽  
Minh Luu
Keyword(s):  

1989 ◽  
Vol 13 (11) ◽  
pp. 989
Author(s):  
Dennis A. Gastineau ◽  
Peter M. Banks ◽  
Danile M. Knowles
Keyword(s):  

2009 ◽  
Vol 66 (1) ◽  
pp. 63-65 ◽  
Author(s):  
Radoje Colovic ◽  
Nada Suvajdzic ◽  
Nikica Grubor ◽  
Natasa Colovic ◽  
Tatjana Terzic

Background. Littoral-cell angioma (LCA) is a recently described benign vascular tumor of the spleen, whose imaging and pathologic characteristics have been discussed only by a few authors. The tumor is characterized by a mixture of papillary and cystic areas lined by neoplastic cells deriving from normal splenic lining - littoral cells. The neoplastic LCA cells express both endothelial and histiocytic antigens associated with CD8 negativity, compared with the normal endothelium of the venous sinuses of the spleen red pulp that only expresses endothelial antigens and CD8 positivity. Therefore, the typical and characteristic immunohistochemical pattern of the LCA is as follows: CD31, CD68, CD163, CD21, FVIII antigen positive; CD34, CD8 negative. Case report. We reported a 60-year-old male with moderate nodular splenomegaly with one large hypoechogenic solid lesion and mild thrombocytopenia in whom the diagnosis of LCA was made after the elective splenectomy. Namely, histopathological and immunohistochemical data allowed a final diagnosis of classical LCA in spite of CD21 negativity. As far as we know this is the first reported CD21-negative LCA patient. Histological specimens were presented and differential diagnoses discussed. Conclusion. Littoral-cell angioma is a very rare benign splenic neoplasm that should be considered in the differential diagnosis of multinodular splenomegaly, particularly if the patient has the signs of hypersplenism.


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