scholarly journals Acetoacetic Acid Measurement

2020 ◽  
Author(s):  
Keyword(s):  



1949 ◽  
Vol 179 (3) ◽  
pp. 1235-1244 ◽  
Author(s):  
Sanford M. Rosenthal


1919 ◽  
Vol 39 (1) ◽  
pp. 23
Author(s):  
Donald D. Van Slyke ◽  
Reginald Fitz


1941 ◽  
Vol 140 (3) ◽  
pp. 811-825
Author(s):  
Alfred E. Koehler ◽  
Emanuel Windsor ◽  
Elsie Hill
Keyword(s):  


2021 ◽  
pp. 8-10
Author(s):  
Sruthi P ◽  
Manzoor Sharieff M ◽  
Prasanth Kumar P ◽  
Vishnu priya V ◽  
Nagarajan N ◽  
...  

Diabetic ketoacidosis (DKA) is the most common complication seen in uncontrolled diabetes mellitus. DKA is most commonly seen with patients of type 1 diabetes. Depletion of Insulin leads to high blood sugars which in turn leads osmotic diuresis, production of ketone bodies i.e, βhydroxybutyric acid and acetoacetic acid, dysregulation of sodium hydrogen exchange mechanism[2]. As a consequence to the above stated mechanisms, cerebral edema has been documented as a fatal complication in DKA. Mortality documented due to cerebral edema is 21-25%[4].



1962 ◽  
Vol 13 (2) ◽  
pp. 307 ◽  
Author(s):  
RL Reid

Acetone comprised 0–40% (average 18%) of the acetoacetic acid plus acetone fraction in sheep blood, in which the level of this fraction was 0.6–5.2 mg % (as acetone). Acetoacetic acid was largely converted to acetone during storage of blood at –20°C, with intermittent thawing for analysis. Concentrations of acetoacetic acid in red cells were similar to those in plasma, but those of ß-hydroxybutyric acid were considerably lower. In contrast to acetoacetic acid, ß-hydroxybutyric acid was virtually absent from foetal blood and from brain tissue. Concentrations of both ketone fractions in liver and muscle tissue were about one-half the blood concentrations. The renal clearance of acetoacetic acid plus acetone in hyperketonaemic pregnant ewes was independent of blood level up to 20 mg % and was little affected by rate of urine flow. Clearance values were in the range of 4–9 ml per min, which indicates that most of the acetoacetic acid filtered at the glomeruli is absorbed by the renal tubules. Renal clearance of ß-hydroxybutyric acid was dependent on blood level and was more affected by rate of urine flow than that of acetoacetic acid. Very little ß-hydroxybutyric acid appeared in the urine when blood levels were below 15 mg %. Clearance increased as blood concentration rose above this level, and reached maximum values, mostly of 3–5 ml per min, at blood levels exceeding 30 mg %.



1995 ◽  
Vol 8 (1) ◽  
pp. 43-44 ◽  
Author(s):  
KOJI ARIMITSU ◽  
KAZUAKI KUDO ◽  
HIRONORI OHMORI ◽  
KUNIHIRO ICHIMURA


1982 ◽  
Vol 13 (46) ◽  
Author(s):  
G. O. TOROSYAN ◽  
G. G. GEKCHYAN ◽  
G. A. PANOSYAN ◽  
R. T. GRIGORYAN ◽  
A. T. BABAYAN


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